• Mashup Score: 1

    IntroductionLeft ventricular hypertrophy (LVH) detection techniques on by electrocardiogram (ECG) are cumbersome to remember with modest performance. This study validated a rapid technique for LVH detection and measured its performance against other techniques.MethodsThis was a retrospective cohort study of patients at Stanford Health Care who received ECGs and resting transthoracic echocardiograms (TTE) from 2006 through 2018. The novel technique, Witteles-Somani (WS), assesses for S- and R-wave overlap on adjacent precordial leads. The WS, Sokolow-Lyon, Cornell, and Peguero-Lo Presti techniques were algorithmically implemented on ECGs. Classification metrics, receiver-operator curves, and Pearson correlations measured performance. Age- and sex-adjusted Cox proportional hazard models evaluated associations between incident cardiovascular outcomes and each technique.ResultsA total of 53,333 ECG-TTE pairs from 18,873 patients were identified. Of all ECG-TTE pairs, 21,638 (40.6%) had TTE

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    • (2/2) Sulaiman took a joke I routinely made during @StanfordDeptMed #CCU rounds about the “Witteles criteria” for detecting LVH and actually rigorously tested and proved it. INCREDIBLE! For those interested, just published here: https://t.co/JeyjzUvgI5

  • Mashup Score: 5

    This qualitative study evaluates user-generated, publicly available posts and comments about statin-related topics: ketogenic diets, diabetes, and supplements; statin adverse effects; statin hesitancy; clinical trial appraisals; pharmaceutical industry bias; and red yeast rice.

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    • Incredible work by super⭐️ @StanfordMedRes PGY-2 #SulaimanSomani on this piece in @JAMANetworkOpen on #AI and #statins. Congratulations!!! @FaRodriguezMD @AshishSarraju @HeartBobH @StanfordDeptMed @StanfordChiefs @JAMANetwork https://t.co/YVXvNy4GLC

  • Mashup Score: 12

    A daily 40-mg dose of atorvastatin for 12 months significantly cut incident cardiac dysfunction in patients with lymphoma receiving anthracycline treatment.

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    • RT @Ron_Witteles: Nice article from @medscape covering the STOP-CA trial from #ACC23. https://t.co/5x8bkSbgbQ @TomasNeilan @AnaBaracCardio…

    • Nice article from @medscape covering the STOP-CA trial from #ACC23. https://t.co/5x8bkSbgbQ @TomasNeilan @AnaBaracCardio @gmelendezMD @HanZhuMD @Paul_P_Cheng @JuneWRhee @JJheart_doc @SWaliany @ninianlang @CardioOncology @Dr_Mike_Fradley @SeanM_Wu #CardioOnc

  • Mashup Score: 4

    The concerns range from low levels of evidence for some recommendations to issues of implementation and overreach.

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    • Nice article in ⁦@TCTMD⁩ on the ⁦@escardio⁩ #CardioOnc guidelines, highlighting the recent perspectives in ⁦@JACCJournals⁩ #JACC:CardioOnc. The guidelines are a true triumph, but with some very important words of caution… ⚠️⚠️⚠️ ⁦ https://t.co/u4oLNW2OLY

  • Mashup Score: 6

    IntroductionIt is difficult to assign a precise date to the birth of the field of cardio-oncology. Although cardiac effects of anthracyclines have been known for decades, the field as we now know it truly emerged in the early to mid-2000s, largely in response to recognized cardiac toxicities from trastuzumab and vascular endothelial growth factor (VEGF) inhibitors. Since that time, the field has…

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    • Proud of the series of editorials on the @escardio #CardioOncology guidelines just published in @JACCJournals JACC:CardioOncology. Link attached for ours. The guidelines are a TRUE triumph - but with a major caution⚠️around promoting overscreening. https://t.co/1rawReIb41