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Mashup Score: 200
A monoclonal antibody shows neutralization efficacy against an emerging group 2c BtCoV-422 strain that replicates in primary human airway cells.
Source: www.science.orgCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 19Vaccine-mediated protection against Merbecovirus and Sarbecovirus challenge in mice - 7 month(s) ago
Martinez et al. demonstrate proof of concept that a single ferritin nanoparticle vaccine displaying the receptor-binding domains of MERS-related and SARS-related zoonotic, epidemic, and pandemic coronaviruses elicits broadly cross-reactive binding and neutralizing antibodies against SARS-CoV-2 variants and protects against lethal SARS-CoV and highly pathogenic MERS-CoV disease in mice.
Source: www.cell.comCategories: General Medicine News, Infectious DiseaseTweet-
Our paper describing a ferritin nanoparticle RBD vaccine that protects mice against #SARSCoV and #MERSCoV and neutralizes highly mutated #SARSCoV2 #VOCs is out in @CellReports Team effort with @TheDHVI @aschaefe29 thread👇🏼 https://t.co/ny2GulXDGm
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Mashup Score: 3Center for Systems & Engineering Immunology - 7 month(s) ago
The Yale Center for Systems and Engineering Immunology (CSEI) at the Yale University School of Medicine (YSM) brings together Yale faculty and trainees from
Source: medicine.yale.eduCategories: General Medicine News, Infectious DiseaseTweet-
RT @YaleCSEI: The CSEI website is live! Check it out! @YaleMed @YaleIBIO https://t.co/0Kr5EDdHEX
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Mashup Score: 7Can we control dengue? - 7 month(s) ago
Climate change is affecting temperatures and amount of rainfall in many countries, thus favouring the spread of vector-borne diseases. This year, large dengue outbreaks are occurring in Latin America and southeast Asia. Bangladesh is facing its worst dengue outbreak on record: as of Sept 4, 2023, 133 134 dengue cases have been detected, with 646 deaths. In Cox’s Bazar, where many Rohingya refugees live, as of Aug 30, 2023, 9670 persons (1214 Bangladeshi and 8456 Rohingya) had tested positive for dengue.
Source: www.thelancet.comCategories: Infectious Disease, Latest HeadlinesTweet-
RT @EngEongOoi: Can we control dengue? - The Lancet Infectious Diseases https://t.co/M10AkvLfgo
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Mashup Score: 14
Sankhala et al. use Zika virus as a bait to identify potent neutralizing monoclonal antibodies (mAbs) that are highly specific to Zika virus. These mAbs bind conformational epitopes across the virion dimer-dimer interface and provide protection against infection in a mouse Zika virus challenge model.
Source: www.cell.comCategories: Infectious Disease, Latest HeadlinesTweet-
RT @MGordonJoyce: Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes: Cell Reports https://t.co/BFoKPEVQwd
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Mashup Score: 2
Phospholipid scramblase 1 (PLSCR1), a protein induced by IFNγ, acts as a defence factor against SARS-CoV-2 and other coronaviruses by inhibiting the fusion of the virus with host-cell membranes.
Source: NatureCategories: Infectious Disease, Latest HeadlinesTweet-
RT @WilenLab: https://t.co/KCCPnCQWkv Congrats to Dijin and William from the MacMicking lab identifying PLSCR1 as a host restriction factor…
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Mashup Score: 9El dengue desangra Perú: la enfermedad, alimentada por el cambio climático, deja casi 300 muertos - 10 month(s) ago
El crecimiento exponencial de casos, más de 161.000 este año, está relacionado en parte con el aumento inusual de temperaturas en el país
Source: El País AméricaCategories: Infectious Disease, Latest HeadlinesTweet-
RT @Pepman34: El dengue desangra Perú: la enfermedad, alimentada por el cambio climático, deja casi 300 muertos https://t.co/HZUEySl1mN v…
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Mashup Score: 0Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential - 11 month(s) ago
Despite the wide availability of several safe and effective vaccines that can prevent severe COVID-19 disease, the emergence of SARS-CoV-2 variants of concern (VOC) that can partially evade vaccine immunity remains a global health concern. In addition, the emergence of highly mutated and neutralization-resistant SARS-CoV-2 VOCs such as BA.1 and BA.5 that can partially or fully evade (1) many…
Source: bioRxivCategories: Infectious Disease, Latest HeadlinesTweet-
Our #AViDD has a new paper out. We characterized an oral drug 💊 with broad in vivo efficacy against all tested coronaviruses🦠 “Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential” https://t.co/x3KjmnEkpj
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Mashup Score: 3Sri Lanka dengue outbreak nears 40,000 cases - Outbreak News Today - 11 month(s) ago
NewsDesk @bactiman63 The International Federation of Red Cross And Red Crescent Societies reports dengue cases have been on the rise since the beginning of the year in Sri Lanka. Cases reported are currently three times higher than those recorded in the corresponding period of the last two years. According to the National Dengue Control Unit (NDCU), […]
Source: Outbreak News TodayCategories: Infectious Disease, Latest HeadlinesTweet-
RT @bactiman63: #SriLanka #dengue outbreak nears 40,000 cases https://t.co/i6plvsNW4i
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Mashup Score: 16Vaccine-mediated protection against merbecovirus and sarbecovirus challenge in mice - 12 month(s) ago
The emergence of three distinct highly pathogenic human coronaviruses, SARS-CoV in 2003, MERS-CoV in 2012, and SARS-CoV-2 in 2019, underlines the need to develop broadly active vaccines against the Merbecovirus and Sarbecovirus betacoronavirus subgenera. While SARS-CoV-2 vaccines are highly protective against severe COVID-19 disease, they do not protect against other sarbecoviruses or…
Source: bioRxivCategories: Infectious Disease, Latest HeadlinesTweet-
Our latest paper describing #universal #CoV vaccine that can protect against #MERSCoV and #SARSCoV is now out in #preprint @YaleMed Short thread 👇🏼 “Vaccine-mediated protection against merbecovirus and sarbecovirus challenge in mice” https://t.co/g5DvqpY7ld
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Our paper characterizing a MERS-related 🦇 #CoV is out in @ScienceTM ! In this study we evaluated the ability of Bt-CoV 422 to replicate in primary human airway cells partially evade countermeasures. TLDR: merbecoviruses are poised for emergence (1/2) https://t.co/qsCK2yU0pQ