The Human Insulin Thermal Solution project—a private sector initiative to address the thermostability of insulin
Insulin products should be refrigerated at 2–8°C before first use and can be stored at ambient temperatures (ie, 25–30°C) after opening for 4–6 weeks, as recommended by insulin manufacturers. The rate of physical and chemical degradation of insulin increases when the temperature is increased. Adherence to strict cold-storage conditions can be challenging in countries with very hot ambient temperatures, little access to refrigeration, unreliable electricity supply, or poor storage facilities, leading to improper storage of insulin products.