• Mashup Score: 2
    Obesity ‘should not influence’ choice between TNF, non-TNF therapies in RA - 2 year(s) ago

    In patients with rheumatoid arthritis initiating either TNF inhibitors or non-TNF inhibitor biologic therapies, severe obesity and low BMI each impeded treatment response, according to data published in Arthritis Care & Research.The researchers additionally found the efficacy of TNF inhibitor and non-TNF inhibitor therapies to be statistically similar across the range of body mass.

    Source: www.healio.com
    Categories: Latest Headlines, Rheumatology
    Tweet Tweets with this article
    • Profile photo of HealioRheum
      HealioRheum

      New data in @ACR_Journals found that although #Obesity and #underweight affected treatment response for #RheumatoidArthritis patients, efficacy of #TNF inhibitor and non-TNF inhibitor therapies were similar across the range of #BMI #RheumTwitter https://t.co/yQepNt57YE

  • Mashup Score: 0
    Tumor Necrosis Factor - 2 year(s) ago

    As a pleiotropic cytokine, tumor necrosis factor (TNF) is a major player in immunologic functions.

    Source: HMP Global Learning Network
    Categories: Dermatology, Latest Headlines
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    • Profile photo of TheDermEditor
      TheDermEditor

      As a pleiotropic cytokine, tumor necrosis factor (TNF) is a major player in immunologic functions. Check out these professional insights into TNFs here: https://t.co/0QJm7qXLtX #dermtwitter #TNF #dermatology https://t.co/6FizQALxal

  • Mashup Score: 0
    • Profile photo of ARD_BMJ
      ARD_BMJ

      Do immunosuppressive treatments impact #COVID19 clinical outcomes in patients with #rheumatic conditions? ▶️ severe clinical outcomes associated with #infliximab vs #TNF inhibitors ▶️ no difference in #COVID19 compatible symptoms 🔗 https://t.co/6okpOqTZLx https://t.co/Qar34IhkBy

      Read the original tweet here

    Source: Twitter
    Categories: Latest Headlines, Rheumatology
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    • Profile photo of ARD_BMJ
      ARD_BMJ

      ❗ Correction: in our previous weet, it should read as: ▶️ severe clinical outcomes associated with #rituximab vs #TNF inhibitors https://t.co/xoJUJwCTOC

  • Mashup Score: 6
    Incidence of COVID-19 in patients treated with infliximab compared with patients treated with rituximab - 2 year(s) ago

    Objective To determine whether patients with inflammatory autoimmune diseases treated with rituximab (RTX) have more severe forms of COVID-19 compared with patients treated with anticytokine therapies, such as Tumour Necrosis Factor (TNF) inhibitors. Methods We included all patients who were on either RTX or infliximab (IFX) in two Swiss cantons during the first wave of the COVID-19 pandemic. We…

    Source: RMD Open
    Categories: Latest Headlines, Rheumatology
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    • Profile photo of ARD_BMJ
      ARD_BMJ

      Do immunosuppressive treatments impact #COVID19 clinical outcomes in patients with #rheumatic conditions? ▶️ severe clinical outcomes associated with #infliximab vs #TNF inhibitors ▶️ no difference in #COVID19 compatible symptoms 🔗 https://t.co/6okpOqTZLx https://t.co/Qar34IhkBy

  • Mashup Score: 2
    Current issue: Trends in Immunology - 2 year(s) ago

    Apart, together: coping with the COVID-19 pandemicDecember 2021 marks 2 years since the first reports of a coronavirus outbreak were covered by a handful of international media outlets. Few could have envisioned what would transpire over the coming months and none can accurately predict how things will unfold in years to come. The SARS-CoV-2 pandemic continues, diminished in some places, unabated…

    Source: www.cell.com
    Categories: Allergy-Immunology, Latest Headlines
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    • Profile photo of TrendsImmuno
      TrendsImmuno

      Read Dec issue! @TrendsImmuno #COVID19, #TCR signaling, #RNA & #inflammation, #gene conservation & immunology, baby skin #bacteria, #hematopoiesis, #cDC1 & #cancer #immunotherapy, #TNF #cytotoxicity, single @Bcell #Ab discovery, #RBC & #SLE, #methylation.. https://t.co/LUxfleRGGy https://t.co/hsTxph4QWO

  • Mashup Score: 0
    Treat-to-target TNF-inhibitor tapering does not negatively impact PsA, axial SpA activity - 3 year(s) ago

    Treat-to-target tapering of TNF inhibitors in patients with psoriatic arthritis or axial spondyloarthritis does not result in any negative impact on disease activity, compared with the full dose, according to data published in Rheumatology. “Tumor necrosis factor inhibitors (TNFi) have proven safe and effective in the treatment of spondyloarthritis (SpA), including psoriatic arthritis (PsA)

    Source: www.healio.com
    Categories: Latest Headlines, Rheumatology
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    • Profile photo of HealioRheum
      HealioRheum

      Disease activity-guided dose optimization was found to be effective and safe in #PsoriaticArthritis and axial #Spondyloarthritis patients who are doing well on their #TNF inhibitors https://t.co/DnyRiolkwY

  • Mashup Score: 0
    Lymphoma complicating rheumatoid arthritis: results from a French case–control study - 3 year(s) ago

    Objectives To study the characteristics of B-cell non-Hodgkin’s lymphoma (NHL) or Hodgkin lymphoma complicating rheumatoid arthritis (RA) and to identify RA-related factors associated with their occurrence. Methods A multicentre case–control study was performed in France. Cases were patients with RA fulfilling ACR-EULAR 2010 criteria in whom B-cell NHL or Hodgkin lymphoma developed after the…

    Source: RMD Open
    Categories: Latest Headlines, Rheumatology
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    • Profile photo of ARD_BMJ
      ARD_BMJ

      Lymphoma complicating rheumatoid arthritis: results from a French case–control study ▶️#lymphoma risk associated with high disease activity and severity ▶️no effect of #methotrexate or #TNF blockers 🔗https://t.co/KVdXmEWTCM @crichez33 https://t.co/4bc7Bnj8QN

  • Mashup Score: 2
    Long-term TNF inhibitor use in rheumatoid arthritis not linked to increased cancer risk - 3 year(s) ago

    There is no increased risk for cancer overall associated with the long-term use of TNF inhibitors for rheumatoid arthritis, according to data published in Rheumatology. “Studies on cancer risks with TNF inhibitors have been based on relatively short follow-up (few studies with a medium follow-up of more than 3 years), thus leaving questions on longer-term risks essentially

    Source: www.healio.com
    Categories: Latest Headlines, Rheumatology
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    • Profile photo of HealioRheum
      HealioRheum

      New data in @RheumJnl reveals long-term #TNF inhibitor use in #RheumatoidArthritis is not linked to increased #cancer risk https://t.co/6WQqAln0Ji

  • Mashup Score: 1
    Insights into the biology and therapeutic implications of TNF and regulatory T cells - 3 year(s) ago

    Tumour necrosis factor (TNF) inhibitors are effective treatments for autoimmune and rheumatic diseases. Here, Salomon reviews the complex pro-inflammatory and regulatory roles of TNF, highlighting its effects on the expansion, differentiation and suppressive function of regulatory T cells and their implications for the design of future anti-TNF agents.

    Source: Nature Reviews Rheumatology
    Categories: Latest Headlines, Rheumatology
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    • Profile photo of NatRevRheumatol
      NatRevRheumatol

      Online now! Insights into the biology and therapeutic implications of TNF and regulatory T cells from Benoit Salomon #RheumTwitter #rheumtology #Tregs #TNF https://t.co/n0NT8XEDkk https://t.co/mvMp1xz0T3

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