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Mashup Score: 6Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein - Nature Communications - 1 year(s) ago
In this paper, the authors use hydrogen-deuterium exchange mass spectrometry to describe how the SARS-CoV-2 spike glycoprotein has evolved its structural dynamics features and receptor binding capability from the emergence of the original Wuhan isolate to the recent omicron variant. The findings reported shed light on the evolution of SARS-CoV-2 in the human population and the mechanisms of…
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Compound in the herb rosemary may be useful against COVID-19 and other inflammatory diseases - 2 year(s) ago
Scientists find evidence that carnosic acid can block SARS-CoV-2 infection and reduce inflammation. February 01, 2022 LA JOLLA, CA—A team co-led by scientists at Scripps Research has found evidence that a compound contained in the medicinal and culinary herb rosemary could be a two-pronged weapon against the SARS-CoV-2 coronavirus that causes COVID-19. The scientists, in experiments described…
Source: www.scripps.eduCategories: General Medicine News, Latest HeadlinesTweet-
Team co-led by Prof. Stuart Lipton’s lab has found evidence that a compound contained in the medicinal & culinary herb rosemary could be a weapon against #SARSCoV2. Carnosic acid is both anti-inflammatory & can block #spike protein binding https://t.co/JdpuKmcrQs @MDPIOpenAccess https://t.co/zd2FDByiCM
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Mashup Score: 12
UBC researchers are the first in the world to conduct a molecular-level structural analysis of the omicron variant spike protein.
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
World's first molecular-level analysis of #omicronvariant #spike protein @ubcnews https://t.co/fh9wQagTND
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Mashup Score: 0La proteina Spike, fatti e misfatti · Sfero - 3 year(s) ago
La famosa “spike” è la proteina principale responsabile dell’infettività del coronavirus, perché è soprattutto attraverso di essa che i
Source: SferoCategories: Hematologists1, Latest HeadlinesTweet-
#covid-19 #spike https://t.co/pCaZ7WFFBS
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Mashup Score: 1Martin McKee on "Spike: The virus versus the people" - The BMJ - 3 year(s) ago
How was it that the United Kingdom did so badly during the initial waves of the covid-19 pandemic? This is a question that has puzzled many people, but not, apparently, […]More…
Source: The BMJCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
RT @DrBirte: Excellent review of @JeremyFarrar and @anjahuja's #Spike by @martinmckee on @bmj_latest https://t.co/y3MycuYYWb
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Mashup Score: 74Human Antibodies Target Many Parts of Coronavirus Spike Protein - 3 year(s) ago
For many people who’ve had COVID-19, the infections were thankfully mild and relatively brief. But these individuals’ immune systems still hold onto enduring clues about how best to neu…
Source: NIH Director's BlogCategories: Healthcare Professionals, Latest HeadlinesTweet-
A new study finds a successful #immune response to #COVID19 involves #antibodies that hit multiple parts of the #spike, not just the RBD. This #basicresearch could point to new ways to treat or prevent COVID19. #NIH https://t.co/Ctuc9YfHR9
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Mashup Score: 31
This striking portrait features the spike protein that crowns SARS-CoV-2, the coronavirus that causes COVID-19. This highly flexible protein has settled here into one of its many possible conformat…
Source: NIH Director's BlogCategories: Healthcare Professionals, Latest HeadlinesTweet-
New computer simulations of #coronavirus #spike protein in action show it’s protected by sugar chains. Find out how exploiting these chains could lead to improved #COVID19 treatment. #NIH https://t.co/h3kEM0LqEp
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Mashup Score: 5
The protein-based vaccine delivers particles that mimic the shape of a whole virus; early tests in mice suggest it also may work against variants of SARS-CoV-2. March 19, 2021 LA JOLLA, CA—Scientists at Scripps Research have created an experimental COVID-19 vaccine that works differently than vaccines currently in use—and may provide some important advantages, according to…
Source: www.scripps.eduCategories: General Medicine News, Latest HeadlinesTweet-
Unlike current #COVID19 #vaccines that rely on RNA or viral DNA to instruct cells to create individual #spike proteins, a new protein-based approach developed by @lab_zhu may offer some key advantages with stability and immune response https://t.co/elsykmUeC3 @ScienceAdvances https://t.co/LPGzaSPt38
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Mashup Score: 1
Viruses spread between hosts through particles, but within hosts, viral genomes can spread from cell to cell through fusion, evading antiviral defenses and obviating costly infectious virion production1-3. Billions of electromechanically coupled cardiomyocytes (CMs) make myocardium inherently vul…
Source: www.researchsquare.comCategories: Cardiologists, Latest HeadlinesTweet-
Hi @danmjohnson - here you go. @myosightJWS first submitted in October and has add over 10K views so far. Hope you like the @MayoClinic discovery as much as we do. #SARS_CoV_2 direct #cardiac damage through #Spike-mediated cardiomyocyte fusion https://t.co/WtJAy3xTgX
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Mashup Score: 8Unbiased Screens Show CD8+ T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein - 4 year(s) ago
Ferretti et al. reveal specific SARS-CoV-2 epitopes that are broadly shared by CD8+ T cells of COVID-19 patients but exhibit limited cross-reactivity with seasonal coronaviruses. Most epitopes are located outside of the spike protein, suggesting that next-generation vaccines incorporating these epitopes might be needed to generate more robust and durable immunity.
Source: ImmunityCategories: General Medicine News, Latest HeadlinesTweet-
Unbiased screens uncover specific #SARSCoV2 targets that are broadly shared by CD8+ T cells of #COVID19 patients, ~90% of which are not located in the #Spike protein. Read more in @ImmunityCP https://t.co/4re2LtBlE0 https://t.co/HfREn1xo5b
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Scientists use #HDX mass spectrometry to describe the evolution of the dynamic structural features of #SARSCoV2 #Spike glycoprotein, and provide insights into the mechanisms of emergence of new virus variants. @Val_Calvaresi @wrobel_antoni @A_Politis https://t.co/1Jt34j9m2w https://t.co/C9PRaKM1z8