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Mashup Score: 0Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution - 11 month(s) ago
Single-cell analyses elucidate the chromatin landscape and transcriptional regulation of glioblastoma cellular states and identify a radial glia–like population, providing potential targets to disrupt cell states and improve therapeutic efficacy.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 3Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma - 1 year(s) ago
Single-cell and spatial profiling of tumor-infiltrating B and plasma cells in early-stage lung adenocarcinoma (LUAD) highlights previously unappreciated roles of these cells in the LUAD ecosystem and immunotherapy response.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Heading to the #AACR23 session on #BCell Responses? ICYMI: The #SingleCell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma, by speaker @IamLinghua. https://t.co/xAGuWadQmg #lcsm https://t.co/iqgygWVrmd
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Mashup Score: 0Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution - 1 year(s) ago
Human brain development is underpinned by cellular and molecular reconfigurations continuing into the third decade of life. To reveal cell dynamics or…
Source: www.sciencedirect.comCategories: Healthcare Professionals, Latest HeadlinesTweet-
RESOURCE: Human #PrefrontalCortex #gene regulatory dynamics from gestation to adulthood at #singlecell resolution: https://t.co/pN4JgQbLL6 @CellCellPress #PFC #GeneExpression #Chromatin #TranscriptionFactor #BrainDisease #organoid A single-nucleus resolution #transcriptome… https://t.co/l4jdupBHsG https://t.co/BtOOrJGAIb
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Mashup Score: 7Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution - 1 year(s) ago
Spatial profiling of cutaneous melanoma at the single-cell level provided molecular features of progression and immunosuppression, which include paracrine cytokine signaling and direct immune cell–cell contact.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
For those at the #AACR23 workshop on New Methods in Spatial Imaging, don't miss The Spatial Landscape of Progression and #Immunoediting in Primary #Melanoma at #Singlecell Resolution, by speaker @sorger_peter. https://t.co/ezTj9vYdc6 https://t.co/FtdvZjEqU2
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Mashup Score: 0Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia - Nature Communications - 1 year(s) ago
High hyperdiploid acute lymphoblastic leukaemia (HeH ALL) is driven by nonrandom chromosomal gains, which have been suggested to arise early – even before birth. Here, the authors use single-cell whole genome sequencing and in silico modelling to show that HeH ALL aneuploidies could originate early and follow punctuated evolution.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Analysis of high hyperdiploid #AcuteLymphoblasticLeukemia with #SingleCell #WholeGenomeSequencing and #InSilico modelling supports that chromosome gains could have early origin and follow punctuated #evolution #CancerResearch @natrescancer https://t.co/yzizcnjKy8 https://t.co/B2Ql5Hxs9g
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Mashup Score: 1Sciforum - Genes2023 - 1 year(s) ago
Genes 2023 – Single-Cell Genomics Moving Forward
Source: genes2023.sciforum.netCategories: Future of Medicine, Latest HeadlinesTweet-
Looking forward to contribute to the Genes 2023 - #SingleCell Genomics Moving Forward https://t.co/SaDbE7IvCb #Genes2023 meeting @MDPIOpenAccess @Genes_MDP @sciforum with @HorvathALab @OliverStegle @cendrinou @BReinius @KrasiTsaneva @molina_lab @irenepapatheodo @heinaniemi ! https://t.co/mOoLkKmlPk
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Mashup Score: 15Evolutionary route of nasopharyngeal carcinoma metastasis and its clinical significance - Nature Communications - 1 year(s) ago
It is critical to understand the factors that are associated with nasopharyngeal carcinoma (NPC) progression, metastasis and response to therapy. Here, the authors analyse primary and metastatic NPC samples using bulk and single-cell sequencing, and find two distinct evolutionary routes that lead to metastasis.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Recently published: Lin et al. analyse primary and metastatic #NasopharyngealCarcinoma samples using bulk and #SingleCell sequencing, and find two distinct evolutionary routes that lead to #metastasis #CancerResearch @natrescancer https://t.co/q5QPYleHIY https://t.co/QzpIOAJUeT
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Mashup Score: 1Application of high-throughput single-nucleus DNA sequencing in pancreatic cancer - Nature Communications - 1 year(s) ago
Implementing high-throughput single-cell DNA sequencing for the study of solid tumours has been challenging. Here, the authors present an optimised approach for snap-frozen tissue single nuclei extraction and DNA sequencing, which can be applied to study pancreatic ductal adenocarcinoma evolution and heterogeneity.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Recently published: @haochenz39 and @ciacobu @CpcrMsk et al. present an optimised approach for snap-frozen tissue #SingleNuclei DNA #sequencing and use it to study #PancreaticCancer #clonalevolution #CancerResearch #SingleCell @natrescancer https://t.co/Q48KXcWkWY https://t.co/rkFXpiOeMs
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Mashup Score: 0Conferences | Keystone Symposia - 1 year(s) ago
Privacy Policy Terms of Use © 2023 Keystone Symposia on Molecular and Cellular Biology | Registered 501(c)(3). EIN: 84-1326605
Source: www.keystonesymposia.orgCategories: Genetics, Latest HeadlinesTweet-
Our Senior Editor Dr Mike Fletcher will be attending @KeystoneSymp #SingleCell Biology: From Development to Cancer, this June! Join him to explore emerging #CancerHeterogeneity #CellAtlas research in Keystone! https://t.co/GAPKpwqsVB #KSSingleCell23 https://t.co/K0zSwK1BH5
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Mashup Score: 2
Welcome! You are invited to join a webinar: TMP Distinguished Speaker Seminar Series – Dr. Manel Esteller. After registering, you will receive a confirmation email about joining the webinar.
Source: ZoomCategories: Future of Medicine, Latest HeadlinesTweet-
Excited to deliver today the Translational Molecular Pathology #TMP seminar at the MD Anderson Cancer Center @MDAndersonNews ! #Epigenomics + #Epitranscriptomics + #SingleCell https://t.co/C16CttGw8r https://t.co/xU4OTtWp7F
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Read the article behind the latest cover of Cancer Research— Microenvironment-Driven Dynamic Chromatin Changes in #Glioblastoma Recapitulate Early Neural Development at #SingleCell Resolution, by Pine et al. https://t.co/a4FGYMHd25 @MSKCancerCenter https://t.co/atWs4ZR2Lt