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Mashup Score: 1An unusual tandem kinase fusion protein confers leaf rust resistance in wheat - Nature Genetics - 12 month(s) ago
The resistance gene Lr9, which was introduced into bread wheat from the wild grass species Aegilops umbellulata, encodes an unusual tandem kinase fusion protein that confers wheat leaf rust resistance.
Source: NatureCategories: Genetics, Latest HeadlinesTweet-
See also in @NatureGenet 'An unusual tandem kinase fusion protein confers leaf rust resistance in wheat' by @simonkrattinger Yajun Wang and colleagues: 👇🏽 https://t.co/X2kxVoGfCv
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Mashup Score: 0The wheat stem rust resistance gene Sr43 encodes an unusual protein kinase - Nature Genetics - 12 month(s) ago
The resistance gene Sr43, which was crossed into bread wheat from the wild grass Thinopyrum elongatum, encodes an unusual protein kinase fusion protein that confers wheat stem rust resistance.
Source: NatureCategories: Genetics, Latest HeadlinesTweet-
See also in @NatureGenet : 'The wheat stem rust resistance gene Sr43 encodes an unusual protein kinase' by @BrandeWulff Brian J. Steffenson, Guotai Yu, and team 👇🏾 https://t.co/4PQecMF2rm
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🎉 OUT NOW @NatureGenet 📰 The wheat stem rust resistance gene Sr43 encodes an unusual protein kinase 👫 @BrandeWulff Brian J. Steffenson, Guotai Yu and team 👇🏿 https://t.co/4PQecMF2rm
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Mashup Score: 0Pathogen perception and deception in plant immunity by kinase fusion proteins - Nature Genetics - 12 month(s) ago
Two studies describe kinase fusion proteins (KFPs) that regulate the perception and deception of wheat pathogens. These highlight the emergence of KFPs as plant immune regulators and emphasize the importance of crop wild relatives as a reservoir for resistance breeding and global food security.
Source: NatureCategories: Genetics, Latest HeadlinesTweet-
And don't miss the News & Views by @GittaCoaker and @FahimaTzion ⬇️ https://t.co/vW6i8nTpOG
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And don't miss the News & Views by @GittaCoaker and @FahimaTzion ⬇️ https://t.co/vW6i8nTpOG
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Mashup Score: 3
Single-cell multiomic and functional characterization of human pancreatic islets identifies two beta cell subtypes correlated with type 2 diabetes progression that exhibit distinct gene regulatory programs and electrophysiological phenotypes.
Source: NatureCategories: Genetics, Latest HeadlinesTweet-
🎆 OUT TODAY @NatureGenet 📰 Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes 👩🏾🤝👨🏽 @seb11pr @kjgaulton @msanderlab @GaoweiW @JoshChiou and team 👇🏾 https://t.co/iQfNDnEGHw
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Mashup Score: 6Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture - Nature Genetics - 12 month(s) ago
Analyses of whole-genome and RNA sequencing data from 2,733 African American, Puerto Rican and Mexican American individuals reveal ancestry-specific patterns in the genetic architecture of whole-blood gene expression.
Source: NatureCategories: Genetics, Latest HeadlinesTweet-
💥 OUT TODAY @NatureGenet 📰 Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture 👩🏾🤝👨🏼 @Linda_Kachuri @angelcymak @ziv_elad @EstebanBurchard Christopher R. Gignoux, and team ⬇️ https://t.co/WQRxTukwgz
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Mashup Score: 2The impact of rare protein coding genetic variation on adult cognitive function - Nature Genetics - 12 month(s) ago
Analysis of rare coding variants in the UK Biobank identifies eight genes associated with adult cognitive function, including KDM5B. Rare and common variant signals overlap and contribute additively to the phenotype.
Source: NatureCategories: Genetics, Latest HeadlinesTweet-
🔥 OUT NOW @NatureGenet 📰 The impact of rare protein coding genetic variation on adult cognitive function 👩🏻🤝👨🏾 @heikorunz @ChiayenChen and colleagues 👇🏻 https://t.co/hF2TkvqxuI
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Mashup Score: 1Code deposition is unskippable - Nature Genetics - 12 month(s) ago
As computational analysis becomes ever-more ubiquitous for researchers, the deposition of the underlying code is now an expected part of publication. Shortcomings in code sharing can lead to delays in peer review and publication, as well as reproducibility issues that are easily avoided with author preparation.
Source: NatureCategories: Genetics, Latest HeadlinesTweet-
Code deposition is unskippable https://t.co/q2a4tpGrA8
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Mashup Score: 174Pan-cancer whole-genome comparison of primary and metastatic solid tumours - Nature - 12 month(s) ago
The genomic differences between primary and metastatic tumours are assessed across 23 cancer types using pan-cancer whole-genome analysis.
Source: NatureCategories: Genetics, Latest HeadlinesTweet-
RT @fran_mj88: 🚨 Delighted to share our back-to-back publications in @Nature (https://t.co/CKrJIckHMR) and @NatureGenetics (https://t.co/cK…
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Mashup Score: 5Biobank-scale inference of ancestral recombination graphs enables genealogical analysis of complex traits - Nature Genetics - 1 year(s) ago
ARG-Needle is a method to infer genome-wide genealogies from large-scale genotyping data that can be used in association analyses. Applied to UK Biobank data, genealogy-based testing finds more trait associations than using imputed genotypes.
Source: NatureCategories: Genetics, Latest HeadlinesTweet-
🚨 ONLINE @NatureGenet 📰 Biobank-scale inference of ancestral recombination graphs enables genealogical analysis of complex traits 🧑🏿🤝🧑🏽 @brianczhang @aabiddanda Pier Palamara and team 👇🏿 https://t.co/FJXaWNPrR0
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Mashup Score: 2Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity - Nature Genetics - 1 year(s) ago
Peripheral blood mononuclear cells from 73 Japanese patients with coronavirus disease 2019 (COVID-19) and 75 healthy controls were analyzed using single-cell transcriptomics. Combining these data with genotyping data highlights the interplay between host genetics and the immune response in modulating disease severity.
Source: NatureCategories: Genetics, Latest HeadlinesTweet-
🚨 ONLINE @NatureGenet 📰 Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity 🧑🤝🧑 @okada_yukinori Atsushi Kumanogoh and team 👇🏿 https://t.co/LrqMhC11iC
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✨ ONLINE @NatureGenet 📰 An unusual tandem kinase fusion protein confers leaf rust resistance in wheat 👫 @simonkrattinger Yajun Wang and team 👇 https://t.co/X2kxVoGfCv