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Mashup Score: 1A blood and bronchoalveolar lavage protein signature of rapid FEV1 decline in smoking-associated COPD - Scientific Reports - 12 month(s) ago
Accelerated progression of chronic obstructive pulmonary disease (COPD) is associated with increased risks of hospitalization and death. Prognostic insights into mechanisms and markers of progression could facilitate development of disease-modifying therapies. Although individual biomarkers exhibit some predictive value, performance is modest and their univariate nature limits network-level…
Source: NatureCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0Cognitive Functions Linked to Rare Coding Variants in Sequencing Study - 12 month(s) ago
Researchers used exome sequencing data for hundreds of thousands of individuals to identify rare coding variants and genes associated with three cognitive functional traits.
Source: GenomeWebCategories: Healthcare Professionals, Latest HeadlinesTweet-
#Cognitive Functions Linked to Rare Coding Variants in #Sequencing Study https://t.co/7vdMug0g5F #Exome #UK_Biobank #WES The impact of rare #protein-coding genetic variation on adult #cognitivefunction @NatureGenet https://t.co/NJn7nxfChE #cognition #intelligence #intellect… https://t.co/dhHLCAleJW https://t.co/fvstamHe9G
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Mashup Score: 3Engineered repeat proteins as scaffolds to assemble multi-enzyme systems for efficient cell-free biosynthesis - Nature Communications - 12 month(s) ago
Multi-enzymatic cascades benefit from precise nanometric organization but achieving this using available scaffolds is challenging. Here the authors present strategy for organizing multienzymatic systems using a protein scaffold based on TRAP domains, and demonstrate improved catalytic output.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
TRAP-based scaffolds for improved multi-enzyme cell-free biosynthesis @BioMolNano_bmG #protein scaffolds #multi-enzyme #enzyme immobilization; #Biocatalysis #cofactor regeneration #substrate channeling. https://t.co/HQXf7mhGmS
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Mashup Score: 1130 High Protein Snacks That Are Healthy and Portable - 1 year(s) ago
When hunger strikes, reach for a snack that contains protein. Here are 30 healthy snacks that are easy to grab and guaranteed to satisfy your hunger.
Source: HealthlineCategories: General Medicine News, Latest HeadlinesTweet-
High protein snacks are important to have around when hunger hits between meals, as they keep you full and satisfied. 😋 What's your favorite high #protein snack? https://t.co/9cGnfepUra https://t.co/7lJvJdwN39
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Mashup Score: 11Arsenic, Lead Found in Popular Protein Supplements - 1 year(s) ago
Some protein supplements have a high level of toxic heavy metals, according to a report from the Clean Label Project. Consumer Reports explains what you need to know.
Source: Consumer ReportsCategories: Healthcare Professionals, Latest HeadlinesTweet-
Protein powders are a convenient way to boost protein intake, but they have drawbacks, such as additives, allergens, or heavy metals. Almost all the Clean Label Act tested had 1 or more heavy metal contaminants. More than half had #BPA. #protein https://t.co/NehJrTR67h. https://t.co/MOQKDe8dCz
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Mashup Score: 2
While the coronavirus continues to infect people around the world, researchers at the University of Missouri have identified a specific protein inside the human body that plays a critical role in how the virus spreads from cell to cell after infection — a discovery that will help better understand the COVID-19 disease and could lead to the development of new antiviral drugs in the future. The…
Source: EurekAlert!Categories: General Medicine News, Latest HeadlinesTweet-
Occludin #protein may play a key role in spread of #coronavirus throughout body’s #cells; Finding by @Mizzou researchers gives insight into how the virus spreads throughout the human body, may help development of #antiviral drugs #discoveryresearch https://t.co/tiI9KLJ5xK
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Mashup Score: 12The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity - Nature Structural & Molecular Biology - 1 year(s) ago
Using the site-specific incorporation of isotopically labeled glutamines and NMR, Elena-Real et al. identified helical stability of pathogenic huntingtin exon 1 as a key feature defining the aggregation propensity that triggers Huntington’s disease.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Study reveals the structure of the #protein responsible for #Huntington'sdisease @NatureSMB https://t.co/8IZviSJ75v https://t.co/ritUzwQyCt
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Mashup Score: 1sCD14 and intestinal fatty acid binding protein are elevated in the serum of patients with idiopathic anaphylaxis. - 1 year(s) ago
Intestinal epithelial integrity compromise has been identified in gastrointestinal (GI), atopic, and autoimmune diseases.
Categories: Allergy-Immunology, Latest HeadlinesTweet-
In Press! sCD14 and #intestinal fatty #acid binding #protein are elevated in the #serum of #patients with #idiopathic #anaphylaxis. https://t.co/qjCjvxf7jv
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Mashup Score: 11Investigating the role of a protein in hearing loss - 1 year(s) ago
The fast motor kinetics of prestin, a protein found in the inner ear, is essential for hearing high-frequency sounds, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences.
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
Investigating the role of a #protein in #hearingloss @northwesternu @PNASNews https://t.co/Zcrzt0mIA6
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Mashup Score: 3A Genome-Wide Functional Screen Identifies Enhancer and Protective Genes for Amyloid Beta-Peptide Toxicity - 1 year(s) ago
Alzheimer’s disease (AD) is known to be caused by amyloid β-peptide (Aβ) misfolded into β-sheets, but this knowledge has not yet led to treatments to prevent AD. To identify novel molecular players in Aβ toxicity, we carried out a genome-wide screen in Saccharomyces cerevisiae, using a library of 5154 gene knock-out strains expressing Aβ1–42. We identified 81 mammalian orthologue genes that…
Source: MDPICategories: General Medicine News, Latest HeadlinesTweet-
Researchers identify #newgenes that modulate the toxicity of the #protein β-amyloid, responsible for causing Alzheimer's https://t.co/mOAHvcJRMO https://t.co/EcGoFvhR05
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A #blood and #bronchoalveolar lavage #protein signature of rapid FEV1 decline in #smoking-associated #COPD https://t.co/BSLGr5wWrp https://t.co/Fo025iVlTs