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    School of Nursing, University of Alabama at Birmingham. (P.L.) Department of Biostatistics, University of Alabama at Birmingham. (M.G.) Correspondence to: Pankaj Arora, MD, Division of Cardiovascular Disease, The University of Alabama at Birmingham, 1670 University Blvd, Volker Hall B140, Birmingham, AL 35294-0019. Email Section of Cardiology, Birmingham Veterans Affairs Medical Center, AL (P.A.). For Sources of Funding and Disclosures, see page xxx. This article was sent to Ruth McPherson, MD, PhD,

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    • Just out @Circ_Gen Sex Differences in the Association of Genome-Wide Systolic Blood Pressure #Polygenic Risk Score With #Hypertension. Congrats Dr Pankaj Arora and team! @GenPrecisionMed @AHAScience @uk_biobank #CardioTwitter https://t.co/FBgsKSKxbS https://t.co/LdZ1WaRgfs

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    Background Polygenic risk score (PRS), calculated based on genome-wide association studies (GWASs), can improve breast cancer (BC) risk assessment. To date, most BC GWASs have been performed in individuals of European (EUR) ancestry, and the generalisation of EUR-based PRS to other populations is a major challenge. In this study, we examined the performance of EUR-based BC PRS models in Ashkenazi…

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    • 🔯📈 Evaluation of European-based #Polygenic risk score for #BreastCancer in Ashkenazi Jewish (AJ) women in Israel ➡️ PRSs based on European GWAS data *can* identify AJ women with elevated risk of BC OpenAccess: https://t.co/JKBPUAB0n8 @ShaiCarmi @KyrMichailidou @JneticsUK https://t.co/aVk9WpWJwn

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    This study involving 2 large, community-based, longitudinal, cohort studies whether adding 2 markers—coronary artery calcium score and polygenic risk score—to traditional risk factor–based scores improves predicting coronary heart disease among middle-aged to older adults.

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    • .@NIH_NHLBI-funded: In 2 population-based studies involving 3208 adults aged 45-79 years and of #European ancestry, the coronary artery #calcium score but not the #polygenic risk score improved #coronary #HeartDisease risk discrimination. @HeartDocSadiya https://t.co/ZZLtI8p82u https://t.co/Ah6fQ5s6uH

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    Resources - 1 year(s) ago

    ADHD 2022This set of slides provides an overview of the diagnosis and treatment of ADHD.   It can be used as a presentation meant to be given by someone with prior knowledge of these topics.  Feel free to add or delete slides to this set to accommodate your audience.International Consensus StatementThis set of 370 slides is not meant to be a single presentation.  Instead, it is meant to provide…

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    • #ADHD is real, heritable, and highly #polygenic: ~ 7,000 loci involved. But several genes are key: @NatureGenet #neurogenetics #CBT #FishOil #MachineLearning Great interview! https://t.co/nU0Wui5dnx https://t.co/3etqiQ7Rg5 https://t.co/oQYLUVS29i