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Mashup Score: 0Polygenic risk scores may assist decision-making in primary care - 2 year(s) ago
Researchers said they have developed polygenic risk scores for six common diseases that may offer clinically meaningful information about a person’s disease risk.Findings validating the risk scores were recently published in Nature Medicine. The study authors also developed informational resources to help physicians incorporate the polygenic risk scores into practice.
Source: www.healio.comCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 1A polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening - PubMed - 2 year(s) ago
Polygenic risk scores (PRS) have the potential to identify individuals at risk of diseases, optimizing treatment, and predicting survival outcomes. Here, we construct and validate a genome-wide association study (GWAS) derived PRS for nasopharyngeal carcinoma (NPC), using a multi-center study of six …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet-
A #polygenic #risk #score for #nasopharyngeal #carcinoma shows potential for #risk #stratification and #personalized #screening https://t.co/dE7lcZsBOn https://t.co/FH58AQi4mG
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Mashup Score: 0
While polygenic risk scores (PRSs) enable early identification of genetic risk for chronic obstructive pulmonary disease (COPD), predictive performance is limited when the discovery and target populations are not well matched. Hypothesizing that the biological mechanisms of disease are shared across …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet-
#Polygenic #transcriptome #risk #scores for #COPD and #lung #function improve #cross- #ethnic #portability of prediction in the #NHLBI #TOPMed program https://t.co/mEOaSoy884 https://t.co/p3yaLTe2D6
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Mashup Score: 1Polygenic risk score: a tool ready for clinical use? - 2 year(s) ago
This editorial refers to ‘A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study’, by X.
Source: OUP AcademicCategories: Cardiologists, Latest HeadlinesTweet-
Polygenic risk score as tool ready for clinicians: look at the effects of this risk score on cardiovascular risk between different populations! https://t.co/n4L9ga95El #polygenic #score #cardiovascular #risk #ehj #cardiotwitter @ESC_Journals @escardio https://t.co/iwM0Gkfv0K
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Mashup Score: 18Polygenic risk score: a tool ready for clinical use? - 2 year(s) ago
This editorial refers to ‘A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study’, by X.
Source: OUP AcademicCategories: Cardiology News and Journals, Latest HeadlinesTweet-
RT @ehj_ed: Polygenic risk score: a tool ready for clinical use? Discover more in EHJ! https://t.co/n4L9ga95El #CVD #CAD #risk #polygenic…
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Mashup Score: 2Polygenic risk score: a tool ready for clinical use? - 2 year(s) ago
This editorial refers to ‘A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study’, by X.
Source: OUP AcademicCategories: Cardiologists, Latest HeadlinesTweet-
Polygenic risk score: a tool ready for clinical use? Discover more in EHJ! https://t.co/n4L9ga95El #CVD #CAD #risk #polygenic #SCORE2 #ASCVD #cardiotwitter @escardio @ESC_Journals https://t.co/0iyCjxJsUw
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Mashup Score: 0
Background Greater maternal adiposity before or during pregnancy is associated with greater offspring adiposity throughout childhood, but the extent to which this is due to causal intrauterine or periconceptional mechanisms remains unclear. Here, we use Mendelian randomisation (MR) with polygenic risk scores (PRS) to investigate whether associations between maternal pre-/early pregnancy body mass…
Source: BioMed CentralCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
A Mendelian randomisation using #polygenic risk scores exploring the causal effect of maternal pregnancy #adiposity on offspring adiposity. Read it here: https://t.co/Lm7lzV4QuR https://t.co/sNGYKEX2Fn
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Mashup Score: 11
Our results demonstrated that the NeuralCVD score can estimate cardiovascular risk trajectories for primary prevention. NeuralCVD learns the transition of predictive information from genotype to phenotype and identifies individuals with high genetic predisposition before developing a severe clinical phenotype. This finding could improve the reprioritisation of otherwise low-risk individuals with…
Source: The Lancet Digital HealthCategories: Future of Medicine, Latest HeadlinesTweet-
NEW Research: 'Neural network-based integration of #polygenic and clinical information: development and validation of a #prediction model for 10-year risk of major adverse #cardiac events in the UK Biobank cohort'.@ChariteBerlin @HumboldtUni @UniHeidelberg https://t.co/GcnNq3VixW https://t.co/PIHyxAcYLt
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Mashup Score: 0The First Polygenic Risk Score Baby - 2 year(s) ago
Screenshot from Genomic Prediction presentation
Source: Center for Genetics and SocietyCategories: Genetics, Latest HeadlinesTweet-
The dubious practice of screening #IVF embryos according to #polygenic risk scores made news several times in 2021. This unregulated commercial practice is scientifically and ethically controversial, and a big step toward techno-eugenics. https://t.co/2RtcF28IMW
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Mashup Score: 1A Spotlight On: Polygenic Embryo Screening - Dr. Todd Lencz, Professor at the Feinstein Institutes for Medical Research - Front Line Genomics - 2 year(s) ago
In the latest A Spotlight On interview, we talk with Dr. Todd Lencz about the use and ethics of polygenic embryo screening.
Source: Front Line GenomicsCategories: Latest Headlines, Rare DiseaseTweet-
RT @CarolynRChapman: #pgt #ethics #embryoscreening #polygenic https://t.co/mMRX3h2E7b
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Researchers have developed #polygenic risk scores for six #commondiseases that may offer clinically meaningful information about a person’s #diseaserisk. #genetics @jasonvassy https://t.co/wozGAc4zVF