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Mashup Score: 6Neuromyelitis Optica Spectrum Disorder With Atypical Imaging Features - Practical Neurology - 2 day(s) ago
We present an unusual, diagnostically challenging case of neuromyelitis optica spectrum disorder with a trident sign and nerve root enhancement on imaging.
Source: practicalneurology.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1NMOSD Together - 2 month(s) ago
Learn more about Neuromyelitis Optica Spectrum Disorder, connect with others in the rare neuroimmune disorders community, and raise awareness for NMOSD! No matter where you are in the world, we invite you to join us.
Source: wearesrna.orgCategories: General Medicine News, Rare DiseaseTweet
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Mashup Score: 0ABCs of NMOSD – All Things Relapses - 5 month(s) ago
SRNA’s Krissy Dilger was joined by Dr. Hamza Coban to discuss neuromyelitis optica spectrum disorder (NMOSD) relapses.
Source: wearesrna.orgCategories: General Medicine News, Rare DiseaseTweet
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Mashup Score: 0
In this episode of “ABCs of NMOSD” titled “I-CAN, A Study of Inebilizumab in Children,” Dr. Michael Levy joined Rebecca Whitney of SRNA.
Source: wearesrna.orgCategories: General Medicine News, Rare DiseaseTweet
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Mashup Score: 0Indirect Comparison of 3 Monoclonal Antibodies to Treat AQP4+ NMOSD - Practical Neurology - 7 month(s) ago
A study comparing the relative effectiveness of Uplizna (inebilizumab-cdon; Horizon Therapeutics, Dublin, Ireland) versus Soliris (eculizumab; Alexion
Source: practicalneurology.comCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 42023 RNDS - 8 month(s) ago
The one-day regional in-person educational and advocacy conference for those affected by rare neuroimmune disorders.
Source: SRNACategories: Latest Headlines, Rare DiseaseTweet
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Mashup Score: 10
Background and Objectives Exit strategies such as de-escalations have not been evaluated for rituximab in patients with neuromyelitis optica spectrum disorder (NMOSD). We hypothesized that they are associated with disease reactivations and aimed to estimate this risk. Methods We describe a case series of real-world de-escalations from the French NMOSD registry (NOMADMUS). All patients met the 2015 International Panel for NMO Diagnosis (IPND) diagnostic criteria for NMOSD. A computerized screening of the registry extracted patients with rituximab de-escalations and at least 12 months of subsequent follow-up. We searched for 7 de-escalation regimens: scheduled discontinuations or switches to an oral treatment after single infusion cycles, scheduled discontinuations or switches to an oral treatment after periodic infusions, de-escalations before pregnancies, de-escalations after tolerance issues, and increased infusion intervals. Rituximab discontinuations motivated by inefficacy or for u
Source: n.neurology.orgCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 0Immune Repertoire Profiling Reveals Its Clinical Application Potential and Triggers for Neuromyelitis Optica Spectrum Disorders - 10 month(s) ago
Background and Objectives Neuromyelitis optica spectrum disorders (NMOSD) is widely recognized as a CNS demyelinating disease associated with AQP4-IgG (T cell–dependent antibody), and its trigger is still unclear. In addition, although the treatment of NMOSD currently can rely on traditional immunosuppressive and modulating agents, effective methods to predict the efficacy of these therapeutics…
Categories: Latest Headlines, NeurologyTweet
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Mashup Score: 17
Objective We report a case of biopsy-proven giant cell arteritis after an initial presentation of area postrema syndrome. Methods A 65-year-old man was evaluated using MRI, temporal artery biopsy, and ultrasound. Results The patient presented with refractory nausea, vomiting, and hiccups that caused weight loss without any other neurologic or clinical symptoms. His MRI scan 15 days later…
Categories: Latest Headlines, NeurologyTweet
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Mashup Score: 1
According to results of a study presented at the American Academy of Neurology (AAN) 2023 Annual Meeting, ravulizumab (Ultomiris; Alexion, Boston, MA)
Source: Practical NeurologyCategories: Latest Headlines, NeurologyTweet
Patient reports to ED w/ 2 weeks of radicular back pain & allodynia in the feet. Dr Greenberg, Dr Houston, Dr Spiegler, Dr Thawani, Dr Weinberg, & Dr Kister discuss a challenging case of #NMOSD with atypical imaging. @nyulangone @NYUneurologyres @mssociety https://t.co/OkltaCoreA