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Mashup Score: 2Dialysis Outcomes for Children With Lupus Nephritis Compared to Children With Other Forms of Nephritis: A Retrospective Cohort Study - 2 year(s) ago
Children with lupus nephritis (LN) are at high risk of developing kidney failure requiring initiation of kidney replacement therapy. This study compared outcomes among children with LN on dialysis with children with non-lupus glomerular disease and investigated risk factors for adverse outcomes among children with LN on dialysis.
Categories: Latest Headlines, NephrologyTweet
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Mashup Score: 1
Duane Peters from the Lupus Foundation of America interviews Dr Jim Oates from the Medical University of South Carolina and Ralph H. Johnson VA Medical Center in Charleston, USA. They discuss his pape
Source: SoundCloudCategories: Latest Headlines, RheumatologyTweet-
New #podcast Duane Peters @LupusOrg interviews Dr. Oates to discuss his paper on developing risk prediction models in #lupus #nephritis to predict outcomes at the point of# diagnosis, which can be used as support tool to help inform treatment strategies https://t.co/dyTp4ZQBxA
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Mashup Score: 0High p16INK4a, a marker of cellular senescence, is associated with renal injury, impairment and outcome in lupus nephritis - 3 year(s) ago
Objectives Because a significant fraction of patients with lupus nephritis (LN) develops renal impairment, there is a need to better understand the mechanisms underlying disease progression. Here, we assessed for cellular senescence in the LN kidney, and its association with disease severity and outcome. Methods We enumerated the number of cells positive for p16INK4a protein, a marker of…
Source: RMD OpenCategories: Latest Headlines, RheumatologyTweet-
Check out the our latest research on cellular senescence and #lupus: ▶️p16INK4a-positive cells as #senescence marker in #nephritis ▶️p16INK4a linked with renal fibrosis, CD8+ T cell infiltration and functional impairment 🔗https://t.co/joYf71r8DX https://t.co/HAdA6RKRnX
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Mashup Score: 1Dialysis Outcomes for Children With Lupus Nephritis Compared to Children With Other Forms of Nephritis: A Retrospective Cohort Study - 3 year(s) ago
Children with lupus nephritis (LN) are at high risk of developing end-stage kidney disease (ESKD) requiring dialysis initiation. This study aimed to compare outcomes among children on dialysis with LN to those with non-lupus glomerular disease (NLGD) and to investigate risk factors for adverse outcomes among children with LN on dialysis.
Categories: Latest Headlines, NephrologyTweet-
Dialysis Outcomes for Children With Lupus Nephritis Compared to Children With Other Forms of Nephritis: A Retrospective Cohort Study https://t.co/szKFYrgERO @funsocdoc #lupus #dialysis #nephritis #pedneph https://t.co/7beny7KPu2
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Mashup Score: 11From sequential to combination and personalised therapy in lupus nephritis: moving towards a paradigm shift? - 3 year(s) ago
The current treatment paradigm in lupus nephritis consists of an initial phase aimed at inducing remission and a subsequent remission maintenance phase. With this so-called sequential treatment approach, complete renal response is achieved in a disappointing proportion of 20–30% of the patients within 6–12 months, and 5–20% develop end-stage kidney disease within 10 years. Treat-to-target…
Source: Annals of the Rheumatic DiseasesCategories: Latest Headlines, RheumatologyTweet-
How to choose agents in the changing landscape of #lupus #nephritis? Is precision medicinean option? 🔴Check out the latest viewpoint: From sequential to combination and personalised therapy in lupus nephritis: moving towards a paradigm shift? 🔗https://t.co/yKQ2hJOn4Y
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Mashup Score: 3
Rationale: Immune checkpoint inhibitors are monoclonal antibodies used in the treatment of various types of cancers. The downside of using such molecules is the…
Source: SAGE JournalsCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Find out about a case of acute tubulointerstitial #nephritis in a patient on anti-programmed death-ligand 1. @CSNSCN https://t.co/rXZ9d9aVf5
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Mashup Score: 2
Voclosporin in combination with MMF and low-dose steroids led to a clinically and statistically superior complete renal response rate versus MMF and low-dose steroids alone, with a comparable safety profile. This finding is an important advancement in the treatment of patients with active lupus nephritis.
Source: The LancetCategories: Latest Headlines, RheumatologyTweet-
NEW in @TheLancet—Voclosporin (calcineurin inhibitor) in combination with MMF and low-dose steroids led to superior complete renal response rate versus MMF and low-dose steroids alone, with a comparable safety profile, in patients with #lupus #nephritis https://t.co/Dmv0VGqVdE https://t.co/B31oEh0O24
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Mashup Score: 2
Lupus nephritis is a serious and currently irreversible complication of systemic lupus erythematosus that is a leading cause of mortality. New biomarkers and therapies are being developed to improve the monitoring and treatment of this disease.
Source: Nature Reviews RheumatologyCategories: Latest Headlines, RheumatologyTweet-
Protecting the #kidney in systemic lupus erythematosus: from diagnosis to therapy Catch up on your #lupus #nephritis reading this #WorldLupusDay https://t.co/PFYySsHl3G https://t.co/Zg3NpN5Yom
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Mashup Score: 26Public Health - European Commission - 3 year(s) ago
Union Register of medicinal products
Categories: Latest Headlines, RheumatologyTweet-
RT @Lupusreference: Belimumab has just been approved for #lupus #nephritis in Europe! https://t.co/rTczhhSmN6
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Mashup Score: 0Starting with higher-dose prednisone boosts 1-year renal response in lupus nephritis - 3 year(s) ago
An initial median prednisone dose of 45 mg per day achieved significantly better complete renal response rates at 1 year in patients with new-onset lupus nephritis, according to data published in Arthritis Care & Research. “Given the numerous adverse events that may arise at any time after treatment initiation with glucocorticosteroids, current efforts are focused on minimizing their
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet-
Starting with higher-dose #prednisone boosts 1-year renal response in #lupus #nephritis https://t.co/zBwKtohpr4 https://t.co/Pgz273ME86
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Dialysis Outcomes for Children With Lupus Nephritis Compared to Children With Other Forms of Nephritis: A Retrospective Cohort Study https://t.co/szKFYrgERO @funsocdoc #lupus #dialysis #nephritis #pedneph https://t.co/L6q6BUNFXl