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Mashup Score: 4
Abstract. Clonal hematopoiesis (CH) is an aging-associated condition characterized by the clonal outgrowth of mutated pre-leukemic cells. Individuals with CH are at an increased risk of developing hematopoietic malignancies. Here, we describe a novel animal model carrying a recurrent TET2 missense mutation, frequently found in CH and leukemic patients. In a fashion similar to CH, animals show…
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 3LIGHT (TNFSF14) Costimulation Enhances Myeloid Cell Activation and Antitumor Immunity in the Setting of PD-1/PD-L1 and TIGIT Checkpoint Blockade - 2 year(s) ago
This article is featured in Top Reads , p.[][1] [1]: /lookup/volpage/209/429
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#JI_TopRead from George Fromm @ShattuckLabs | LIGHT (TNFSF14) #costimulation enhances #myeloid cell activation and anti-tumor #immunity in the setting of #PDL1 and TIGIT #checkpointblockade #ReadTheJI #AuthorChoice #TumorImmunology https://t.co/j55qbLY8LY https://t.co/sUCRauTixv
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Mashup Score: 0ASH Clinical News: August 2022 From the Desk Of... - 2 year(s) ago
In this edition of “From the Desk Of…,” ASH Clinical News Editor-in-Chief Aaron Gerds, MD, previews the forthcoming August 2022 issue. Highlights include a…
Source: YouTubeCategories: Hem/Oncs, Latest HeadlinesTweet-
Check out what's to come in our August issue! Highlights include a feature on growing #cannabis use among #hematology patients, as well as studies on #lenalidomide in therapy-related #myeloid #neoplasms and #ivosidenib and #azacitidine in #AML. https://t.co/GBDcnC2f6O
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Mashup Score: 10Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear Cell Renal Cell Carcinoma - 2 year(s) ago
Abstract. It is poorly understood how the tumor immune microenvironment influences disease recurrence in localized clear cell renal cell carcinoma (ccRCC). Here we perform whole-transcriptomic profiling of 236 tumors from patients assigned to the placebo-only arm of a randomized, adjuvant clinical trial for high-risk localized ccRCC. Unbiased pathway analysis identifies myeloid-derived…
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
#ICYMI: A Targetable #Myeloid Inflammatory State Governs Disease Recurrence in Clear Cell #RenalCellCarcinoma, by @philrappold, @arihakimi et al. https://t.co/IxgYkwRxyX @LynVuong @MSKCancerCenter @UrologyMSK https://t.co/SZHVxIwaTa
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Mashup Score: 0Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear Cell Renal Cell Carcinoma - 2 year(s) ago
Abstract. It is poorly understood how the tumor immune microenvironment influences disease recurrence in localized clear cell renal cell carcinoma (ccRCC). Here we perform whole-transcriptomic profiling of 236 tumors from patients assigned to the placebo-only arm of a randomized, adjuvant clinical trial for high-risk localized ccRCC. Unbiased pathway analysis identifies myeloid-derived…
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
A Targetable #Myeloid Inflammatory State Governs Disease Recurrence in Clear Cell #RenalCellCarcinoma, by @philrappold, @arihakimi et al. https://t.co/lKK6nLUS6C @LynVuong @MSKCancerCenter @UrologyMSK https://t.co/56GtIVJaT1
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Mashup Score: 0
The upcoming 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers arising in various organ systems within a single relational database. This paper summarizes the new WHO classification scheme for myeloid and histiocytic/dendritic neoplasms and provides an overview of the principles and rationale…
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet-
long awaited #WHO classification on #myeloid #Histiocytic/Dendritic neoplasms @JoeKhouryMD. Leukemia; https://t.co/S9bMbJ2svr @ASH_hematology @MDAndersonNews @LLSusa @SocietyofHemOnc @ASTRO_org @ILROGTeam @ASCO @LeukemiaRF
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Mashup Score: 4Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer - 2 year(s) ago
Circulating tumor cells highly expressing Enpp1 contribute to local recurrence of breast cancer through immune modulation by increasing haptoglobin expression, which encourages infiltration of myeloid-derived suppressor cells and the formation of neutrophil extracellular traps.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
From the May issue: Tumor ENPP1(CD203a)/Haptoglobin Axis Exploits #Myeloid-Derived Suppressor Cells to Promote Post-#Radiotherapy Local Recurrence in #BreastCancer, by @borjaruiz55 et al. https://t.co/GbZ6hR0zF7 @ClinicaNavarra https://t.co/ti91hOElJr
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Mashup Score: 8Home – Hallmarks of Cancer - 2 year(s) ago
Hallmarks of Cancer
Source: www.cell-symposia.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Chat #Myeloid-t cell interaction in solid tumors with Lisa Coussens @OHSUNews @coussens_lisa this October in San Diego, USA @CellSymposia Hallmarks of Cancer. #CSHallmarks2022 https://t.co/bhQLrO0lJk https://t.co/6RzOCsSZFy
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Mashup Score: 0Home – Hallmarks of Cancer - 2 year(s) ago
Hallmarks of Cancer
Source: www.cell-symposia.comCategories: General Medicine News, Latest HeadlinesTweet-
Chat #Myeloid-t cell interaction in solid tumors with Lisa Coussens @OHSUNews @coussens_lisa this October in San Diego, USA @CellSymposia Hallmarks of Cancer. #CSHallmarks2022 https://t.co/NGLubKjP4Q https://t.co/qbtdJtH0GW
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Mashup Score: 1Lupus Susceptibility Loci Predispose Mice to Clonal Lymphocytic Responses and Myeloid Expansion - 2 year(s) ago
This article is featured in Top Reads , p.[][1] [1]: /lookup/volpage/208/2257
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet-
#JI_TopRead from #AAIFellow Michael Carroll @harvardmed @BostonChildrens: #Lupus susceptibility loci predispose mice to clonal lymphocytic responses and #myeloid expansion | #SLE #Autoimmunity #SingleCellSequencing #BCR #TCR #Immunology #ReadtheJI https://t.co/segcG0JxOb https://t.co/ox15WvMbmJ
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The Impact of Inflammation-induced Tumor Plasticity During #Myeloid Transformation, by @AnnaYeaton, @gcayanan1, @Maguillamot, @iannisaifantis1 et al. https://t.co/lAO4ZANqgI @Perlmutter_CC @nyugrossman @nyulangone #ClonalHematopoiesis https://t.co/D0ER5XPURJ