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Mashup Score: 1Resistant and refractory migraine: clinical presentation, pathophysiology, and management - 4 month(s) ago
Migraine is a leading cause of disability worldwide. A minority of individuals with migraine develop resistant or refractory conditions characterised by ≥ 8 monthly days of debilitating headaches and inadequate response, intolerance, or contraindication to ≥3 or all preventive drug classes, respectively. Resistant and refractory migraine are emerging clinical definitions stemming from better knowledge of the pathophysiology of migraine and from the advent of migraine-specific preventive treatments.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 2
Migraine headaches are considered a leading cause of disability around the world.
Source: www.pharmacytimes.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 8Building a Toolkit for the Treatment of Acute Migraine - 4 month(s) ago
Selecting a treatment plan to deal with acute migraine attacks is like putting together a toolkit of possible therapies which can be individualized for each patient, one expert said.
Source: www.medscape.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 12Brain Talks Podcast - Brain Innovation Days - 4 month(s) ago
Brain Talks is a podcast by Brain Innovation Days, the community of key opinion leaders and stakeholders from the brain innovation world.
Source: www.braininnovationdays.euCategories: General Medicine News, PayerTweet
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Mashup Score: 10Building a Toolkit for the Treatment of Acute Migraine - 4 month(s) ago
Selecting a treatment plan to deal with acute migraine attacks is like putting together a toolkit of possible therapies which can be individualized for each patient, one expert said.
Source: www.medscape.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 3Building a Toolkit for the Treatment of Acute Migraine - 5 month(s) ago
Selecting a treatment plan to deal with acute migraine attacks is like putting together a toolkit of possible therapies which can be individualized for each patient, one expert said.
Source: www.medscape.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 72Combined Impact of Migraine and Pregnancy-Induced Hypertension on Long-term Risk of Premature Myocardial Infarction and Stroke | Neurology - 5 month(s) ago
Background and ObjectivesMigraine and pregnancy-induced hypertension (PIH) are known to increase cardiovascular risk on their own. However, evidence is limited on the combined impact of migraine and PIH on risk of cardiovascular disease. The aim of this …
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 60Simultaneous Comparisons of 25 Acute Migraine Medications Based on 10 Million Users' Self-Reported Records From a Smartphone Application | Neurology - 5 month(s) ago
Background and ObjectivesMany acute treatment options exist for migraine. However, large-scale, head-to-head comparisons of treatment effectiveness from real-world patient experience reports are lacking.MethodsThis is a retrospective analysis of 10,842,…
Source: www.neurology.orgCategories: General Medicine News, NeurologyTweet-
This study analyzed patient-generated real-time records of 10 million #migraine attacks and conducted simultaneous comparisons of 25 acute migraine medications. Triptans, ergots, and antiemetics were found to be the most effective classes of medications: https://t.co/ZyBPKyBx7c https://t.co/hyPSHSPTzd
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Mashup Score: 6When It Comes to Migraine Medication, How Do You Choose? - 5 month(s) ago
With many medications to choose from, doctors need to weigh the pros and cons of each drug to decide on the best approach for the patient.
Source: www.medscape.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 18
Background Chronic migraine, a highly disabling migraine subtype, affects nearly 2% of the general population. Understanding migraine chronification is vital for developing better treatment and prevention strategies. An important factor in the chronification of migraine is the overuse of acute headache medication. However, the mechanisms behind the transformation of episodic migraine to chronic migraine and vice versa have not yet been elucidated. We performed a longitudinal epigenome-wide association study to identify DNA methylation (DNAm) changes associated with treatment response in patients with chronic migraine and medication overuse as part of the Chronification and Reversibility of Migraine clinical trial. Blood was taken from patients with chronic migraine (n = 98) at baseline and after a 12-week medication withdrawal period. Treatment responders, patients with ≥ 50% reduction in monthly headache days (MHD), were compared with non-responders to identify DNAm changes associated
Categories: General Medicine News, General NewsTweet
Editor pick from January issue @Simona_Sacco_ & coll Reviewed the clinical scenarios, mechanisms, and therapeutic strategies specific to resistant and refractory #Migraine Read https://t.co/ZIVg7QZX6j https://t.co/Yu9C8H6mPy