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Mashup Score: 0Polymorphic variants involved in methylation regulation: a strategy to discover risk loci for pancreatic ductal adenocarcinoma - 12 month(s) ago
Introduction Only a small number of risk factors for pancreatic ductal adenocarcinoma (PDAC) has been established. Several studies identified a role of epigenetics and of deregulation of DNA methylation. DNA methylation is variable across a lifetime and in different tissues; nevertheless, its levels can be regulated by genetic variants like methylation quantitative trait loci (mQTLs), which can…
Source: Journal of Medical GeneticsCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0Molecular characterization of Richter syndrome identifies de novo diffuse large B-cell lymphomas with poor prognosis - Nature Communications - 1 year(s) ago
Richter syndrome (RS) is the transformation of chronic lymphocytic leukaemia (CLL) into aggressive lymphoma, in most cases diffuse large B-cell lymphoma (DLBCL). Here, the authors characterize the DNA methylation and transcriptomic profiles of RS samples, find a clonally-related CLL epigenetic imprint, and develop classifiers for “RS-type” de novo DLBCLs.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Recently published: #Transcriptomic and DNA #methylation analysis of #RichterSyndrome reveals #CLL #epigenetic imprint and allows developing a classifier to find this malignancy among #DLBCL cases #leukemia #lymphoma #CancerResearch @natrescancer https://t.co/iXBR5mgtlj https://t.co/GGOIhoM2Xp
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Mashup Score: 1Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome - 1 year(s) ago
DNA methylation, one of the best characterized epigenetic marks in the human genome, plays a pivotal role in gene transcription regulation and other biological processes in humans. On top of that, …
Source: Taylor & FrancisCategories: Future of Medicine, Latest HeadlinesTweet-
An illustrated timeline of the @illumina #DNA #methylation microarrays that our group have validated throughout the years, drawing by @Yoana22v https://t.co/Z2ijJfOs4Z https://t.co/mVIrXfu2G1
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Mashup Score: 3Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome - 1 year(s) ago
DNA methylation, one of the best characterized epigenetic marks in the human genome, plays a pivotal role in gene transcription regulation and other biological processes in humans. On top of that, …
Source: Taylor & FrancisCategories: Future of Medicine, Latest HeadlinesTweet-
We are trendy ! Happy to learn that our validation of new @illumina EPIC DNA #methylation #microarray (900K EPIC v2) in Epigenetics journal @tandfonline is one of the hottest papers by @altmetric; great work by @A_Nogueca @carlosgarciapri @DamianaAlvarez1 https://t.co/yIXFqOLFeu https://t.co/4lGCzmoowt
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Mashup Score: 2Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome - 1 year(s) ago
DNA methylation, one of the best characterized epigenetic marks in the human genome, plays a pivotal role in gene transcription regulation and other biological processes in humans. On top of that, …
Source: Taylor & FrancisCategories: Future of Medicine, Latest HeadlinesTweet-
You have been upgraded ! Our validation of the new DNA #methylation #microarray from @illumina, the 900K EPIC v2 ! Article in the open access journal #Epigenetics @tandfonline https://t.co/Z2ijJfOs4Z https://t.co/K05T1D2OiW
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Mashup Score: 1MSIMEP: Predicting microsatellite instability from microarray DNA methylation tumor profiles - 1 year(s) ago
Medical informatics; Genomic analysis; Cancer systems biology.
Source: iScienceCategories: Future of Medicine, Latest HeadlinesTweet-
Helping in @iScience_CP @CellPressNews study led by Rafael López-López @imos_indo and Juan Ruiz-Bañobre @oncomet_ @cimususc @idis_research @UniversidadeUSCto @ciberonc showing how DNA #methylation predicts #microsatellite instability in #cancer https://t.co/cjy4NTaFLy https://t.co/YznUL6Gj55
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Mashup Score: 0
Rats with fertility issues after their great-great-grandmothers were exposed to pesticides. Mice suffering from obesity and liver disease five generations after an ancestor drank water laced with a chemical used to coat ship hulls. All without detectable genetic changes.
Source: STATCategories: Healthcare Professionals, Latest HeadlinesTweet-
New mouse study shows genes aren’t only way to pass #obesity to next generation https://t.co/oaeftwtOEG via @statnews #PotatoFamine Transgenerational inheritance of acquired #epigenetic signatures at #CpG islands in mice https://t.co/4vOJ1Xc4Mz #DNA #methylation https://t.co/iBVz0rJ0d6
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Mashup Score: 0
BackgroundFine particulate matter (PM2.5) is a crucial risk factor for chronic obstructive pulmonary disease (COPD). However, the mechanisms whereby PM2.5 contribute to COPD risk have not been fully elucidated. Accumulating evidence suggests that epigenetics, including DNA methylation, play an important role in this process; however, the association between PM2.5 exposure and genome-wide DNA…
Source: FrontiersCategories: Latest Headlines, PulmonologyTweet-
Short-term #exposure to fine particulate matter and #genome-wide #DNA #methylation in chronic obstructive #pulmonary #disease: A panel study conducted in Beijing, China #COPD #lung https://t.co/6kjn8jW7ic https://t.co/GXU6YoWm2t
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Mashup Score: 0Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome - 1 year(s) ago
Mouse has been extensively used as a model organism in many studies to characterize biological pathways and drug effects and to mimic human diseases. Similar DNA sequences between both species faci…
Source: Taylor & FrancisCategories: Future of Medicine, Latest HeadlinesTweet-
Glad to know that our validation of the @illumina #Infinium DNA #methylation #mouse #microarray #BeadChip is the 2nd most read article in 2022 of #Epigenetics @tandfonline; congrats to the 1st by Randy Jirtle, Cathrine Hoyo @ncsu and the #imprintome https://t.co/nejxWdFKqH https://t.co/2UULmUvJS8
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Mashup Score: 0A DNA methylation atlas of normal human cell types - Nature - 1 year(s) ago
We describe a human DNA methylome atlas based on deep whole-genome bisulfite sequencing, allowing fragment-level analysis of cell-type-specific markers and providing an essential resource for studies of gene regulation and for deconvolution of cell mixtures and liquid biopsies.
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet-
A DNA #methylation atlas of normal human cell types https://t.co/6Nrgd3fEHt
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Polymorphic variants involved in #methylation regulation: a strategy to discover risk loci for pancreatic ductal adenocarcinoma https://t.co/RRRfwgAHMs #PancreaticCancer #Cancer #Genomics pic: @genome_gov https://t.co/9xF6psRnAu