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Mashup Score: 1
Objective To compare the effectiveness of tumor necrosis factor inhibitors (TNFi) ± comedication and methotrexate (MTX) monotherapy between patients with adult juvenile idiopathic arthritis (JIA) and patients with rheumatoid arthritis (RA). Methods Adult patients with JIA and RA were identified from the Norwegian Antirheumatic Drug Register (NOR-DMARD) register. Disease activity measurements at…
Source: The Journal of RheumatologyCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0Olokizumab effective in patients with rheumatoid arthritis unresponsive to TNF inhibitors - 1 year(s) ago
In patients with rheumatoid arthritis who failed to respond to TNF inhibitors, olokizumab is effective and carries an acceptable safety risk, especially when paired with methotrexate, according to data published in Clinical Rheumatology. “Despite the advancement in the DMARDs, less than 50% of patients with RA are in remission, and 10-20% are refractory to the available treatment
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet-
ICYMI: In patients with rheumatoid #arthritis who failed to respond to TNF inhibitors, olokizumab is effective and carries an acceptable safety risk, especially when paired with #methotrexate @TantaUniversity https://t.co/FaIAbgdkba
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Mashup Score: 1Olokizumab effective in patients with rheumatoid arthritis unresponsive to TNF inhibitors - 1 year(s) ago
In patients with rheumatoid arthritis who failed to respond to TNF inhibitors, olokizumab is effective and carries an acceptable safety risk, especially when paired with methotrexate, according to data published in Clinical Rheumatology. “Despite the advancement in the DMARDs, less than 50% of patients with RA are in remission, and 10-20% are refractory to the available treatment
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet-
In patients with rheumatoid #arthritis who failed to respond to TNF inhibitors, olokizumab is effective and carries an acceptable safety risk, especially when paired with #methotrexate @TantaUniversity https://t.co/FaIAbgdkba
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Mashup Score: 0
The MIRACLE study showed that the efficacy of adalimumab combined with reduced methotrexate dose was not inferior to that with the maximum tolerated methotrexate dose, with a tendency to a better safety profile.
Source: The Lancet RheumatologyCategories: Latest Headlines, RheumatologyTweet-
NEW RESEARCH—What is the optimal dose of #methotrexate to administer with a TNF inhibitor? The MIRACLE trial shows that adalimumab + reduced-dose methotrexate is non-inferior to adalimumab + maximal-dose methotrexate in patients with #rheumatoidarthritis https://t.co/RofdRqNbvG https://t.co/LRdzvVKQae
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Mashup Score: 0How Long Should Methotrexate Be Held Following Seasonal Vaccinations? - The Rheumatologist - 1 year(s) ago
Vaccinations against preventable diseases, including seasonal influenza, are strongly recommended for patients with rheumatoid arthritis (RA), who are at increased risk of infections as a result of underlying immune dysfunction and treatment-induced immunosuppression. Park et al. conducted this clinical trial to investigate whether discontinuing methotrexate for one week after seasonal influenza…
Source: The RheumatologistCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
How long should #methotrexate be held following seasonal vaccinations? Find out more in The Rheumatologist, featuring research from Arthritis & Rheumatology: https://t.co/OgNUppLG0R @ACR_Journals @ACRheum #OpenAccess #RheumTwitter https://t.co/Iqt2gQE9QH
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Mashup Score: 1Busting the myth of methotrexate chronic hepatotoxicity - Nature Reviews Rheumatology - 1 year(s) ago
Methotrexate is commonly used in the treatment of inflammatory rheumatic diseases. In this Review, the authors discuss the potential hepatotoxicity of methotrexate, with particular consideration of the role of chronic liver disease, and suggest screening and monitoring strategies for patients receiving methotrexate.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
#FebruaryIssue | In this #Review, the authors discuss the evidence relating to #methotrexate #hepatotoxicity, with particular reference to non-alcoholic fatty liver disease, (#NAFLD), and suggest strategies for screening and monitoring of patients. https://t.co/CMeDb15vap https://t.co/P3ccVhJEWT
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Mashup Score: 0Nature Reviews Rheumatology - Volume 19 Issue 2, February 2023 - 1 year(s) ago
Inspired by the Review on p78.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
Our #FebruaryIssue is out now! Featuring Year in Review articles as well as Reviews on the early phase of #bone regeneration, the myth of #methotrexate chronic #hepatotoxicity and #pathogenesis and #treatment of #vascular #Behçet syndrome https://t.co/ObW7nrFUnA https://t.co/wrW9rc3hmB
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Mashup Score: 0Pegloticase and Methotrexate Co-Therapy Improved Urate Burden, Patient-Reported Outcomes in Gout - 1 year(s) ago
Serum urate rapidly declined after initiation of pegloticase and methotrexate therapy and was maintained well below ≥ 6 mg/dL, an indicator of uncontrolled gout, throughout the study.
Source: HCP LiveCategories: Latest Headlines, RheumatologyTweet-
Adult patients with uncontrolled #gout were included in a multi-center efficacy and safety study evaluating pegloticase and #methotrexate co-therapy. Learn more: https://t.co/k6VnhzJSea
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Mashup Score: 2
Objective To determine the risk of not being able to sustain remission after tapering methotrexate (MTX) from targeted therapy in patients with controlled rheumatoid arthritis (RA). Methods A systematic literature search was conducted in MEDLINE, Embase, and the Cochrane Library for studies reporting remission outcomes after tapering MTX from targeted therapies in RA. Full-text articles and…
Source: The Journal of RheumatologyCategories: Latest Headlines, RheumatologyTweet-
Research Article Can Patients With Controlled Rheumatoid Arthritis Taper Methotrexate From Targeted Therapy and Sustain Remission? A Systematic Review and Metaanalysis 📰 https://t.co/Cf7xXlfgjg #rheumatoidarthritis #methotrexate #remission https://t.co/5h7h7R5W5z
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Mashup Score: 0
PsA linked with more side effects than RA overall; smaller differences with TNFi
Source: www.medpagetoday.comCategories: General Medicine News, Latest HeadlinesTweet-
What were the most common side effects and how did they compare between the two #diseases? #PsoriaticArthritis #RheumatoidArthritis #Methotrexate #Rheumatology @ACRheum Read more: https://t.co/eZgWQYwQWw https://t.co/7bNCp1bOuS
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Open Access Treatment Response to Tumor Necrosis Factor Inhibitors and Methotrexate Monotherapy in Adults With Juvenile Idiopathic Arthritis: Data From NOR-DMARD 📰 https://t.co/7wUSgIFsHw #tumornecrosisfactorinhibitors #methotrexate #juvenileidiopathicarthritis https://t.co/kROieDfoCh