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Mashup Score: 21
Osaka University researchers have discovered liver resident macrophages’ pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 16Exploring how the liver immune system eats up 'bad cholesterol' - 2 month(s) ago
A new study from Karolinska Institutet in Sweden reveals that immune cells in the liver react to high cholesterol levels and eat up excess cholesterol that can otherwise cause damage to arteries. The …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 29Longitudinal Outcomes Associated With Metabolic Dysfunction-Associated Steatotic Liver Disease: A Meta-analysis of 129 Studies - 2 month(s) ago
The progression of metabolic dysfunction-associated steatotic liver disease (MASLD) has been found to manifest in a series of hepatic and extrahepatic complications. A comprehensive meta-analysis of the longitudinal outcomes associated with MASLD has yet to be conducted.
Source: www.cghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 0
HealthFLD, a fully automated AI software for liver attenuation analysis from CT scans, has received FDA 510(k) clearance for use in the general population.
Source: www.hcplive.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 15
The function of cholinergic anti-inflammatory pathway (CAP) in acute liver failure (ALF) with inflammatory storm remains indefinite. The liver-gut axis has been proved to be crucial for liver homeostasis. Investigation about CAP regulation on liver-gut axis would enrich our understanding over cholinergic anti-inflammatory mechanism.
Source: www.cmghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 15Research into autoimmune liver condition suggests unique cell movements may drive disease - 3 month(s) ago
Research suggests that a recent understanding of cell movements may help shed light on the mechanisms driving primary biliary cholangitis (PBC), an autoimmune disease that attacks the bile ducts of the …
Source: medicalxpress.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 13
Scientific Reports – Visualization of hydrocarbon chain length and degree of saturation of fatty acids in mouse livers by combining near-infrared hyperspectral imaging and machine learning
Source: www.nature.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 10
### What you need to know Liver cirrhosis affects 110 people per 100 000 in the UK1 and is closely linked with deprivation. The British Liver Trust2 estimates premature deaths from liver disease to be four times higher in the most deprived areas compared with the most affluent. Early identification and management can delay decompensation events such as variceal bleeding, ascites, and hepatic encephalopathy, leading to longer, better quality life for people with liver disease. In 2015, the National Institute for Health and Care Excellence (NICE) first published guidance on the assessment and early management of cirrhosis in people over 16. This article summarises updated 2023 recommendations, focusing on managing complications, and appraises new evidence related to the effectiveness of non-selective beta blockers (NSBBs) for the primary prevention of decompensation in people with cirrhosis.3 The new guidance also updates recommendations about prevention of variceal bleeding in people wi
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 4T Cell CEACAM1–TIM-3 Crosstalk Alleviates Liver Transplant Injury in Mice and Humans - 5 month(s) ago
Recipient-derived T cell carcinoembryonic antigen-related cell adhesion molecule 1 signaling alleviates liver transplant injury by promoting T cell immunoglobulin domain and mucin domain-containing protein 3, which by interacting with hepatic carcinoembryonic antigen-related cell adhesion molecule 1 suppresses nuclear factor-κB activation in Kupffer cells.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 13Genetic ablation of C/EBPα-p300 pathway blocks development of obese pregnancy associated liver disorders in offspring. - 6 month(s) ago
Obese and overweight expectant mothers lead to the development of fatty liver in their children. We found that activation of C/EBPα-p300 pathway is the cause of fatty liver in offspring and that, ablation of this pathway prevents fatty liver.
Source: www.cmghjournal.orgCategories: General Medicine News, GastroenterologyTweet
Identifying a new #liver defender: The role of resident macrophages @osaka_univ @nature https://t.co/spxT3LhSR6