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Mashup Score: 1Please wait whilst we redirect you - 2 year(s) ago
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Source: www.sciencedirect.comCategories: Latest Headlines, PediatricsTweet
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Mashup Score: 2
Vaccination with UVC-attenuated N americanus larvae is well tolerated, induces humoral and cellular responses to hookworm antigens, and reduces larval output after challenge with unattenuated larvae. Larger studies are required to confirm protective efficacy.
Source: The Lancet Infectious DiseasesCategories: Infectious Disease, Latest HeadlinesTweet-
New research Article: Vaccination of human participants with attenuated Necator americanus #hookworm larvae and human challenge in Australia: a dose-finding study and randomised, placebo-controlled, phase 1 trial https://t.co/Z6Edj75fGS
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Mashup Score: 0
Soil-transmitted helminths (STHs) infect almost 1·5 billion people worldwide. The control of STH infections is based on preventive chemotherapy using either albendazole or mebendazole. Before being widely used, a sufficient body of evidence on efficacy, safety and acceptability is warranted for the new chewable child-friendly formulation of mebendazole that was recently developed.
Source: EClinicalMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Research Article: #Efficacy, #safety and acceptability of a new chewable formulation versus the solid tablet of #mebendazole against #hookworm infections in #Children : An open-label, randomized controlled trial #openaccess https://t.co/55lVkPLOkC
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Mashup Score: 10Hookworm Treatment for Relapsing Multiple Sclerosis - 4 year(s) ago
This randomized clinical trial assesses the effect of hookworm treatment on magnetic resonance imaging activity and T regulatory cells in British patients with relapsing multiple sclerosis.
Source: jamanetwork.comCategories: Latest Headlines, NeurologyTweet-
Study suggests a possible, albeit mild, therapeutic effect of #hookworm infection in relapsing #multiplesclerosis that warrants further study https://t.co/FNsNyBIax0
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Mashup Score: 0Hookworm Vaccine Candidate Clears Phase I Hurdles - 4 year(s) ago
An estimated 450 million people suffer from hookworm infection each year, but a new study suggests it may soon be possible to vaccinate against the infection.
Source: ContagionLiveCategories: Infectious Disease, Latest HeadlinesTweet-
Investigators say a combination #hookworm #vaccine was safe and well-tolerated in a phase I trial in Gabon https://t.co/uArEQ3DcCQ
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Mashup Score: 2Hookworm Vaccine Candidate Clears Phase I Hurdles - 4 year(s) ago
An estimated 450 million people suffer from hookworm infection each year, but a new study suggests it may soon be possible to vaccinate against the infection.
Source: ContagionLiveCategories: Infectious Disease, Latest HeadlinesTweet-
Patients in a new phase I trial of a #hookworm #vaccine had higher-than-baseline levels of IgG, even 6 months following the administration of the final dose, according to a new report in @TheLancetInfDis https://t.co/uArEQ3DcCQ
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Mashup Score: 1
Hookworms cause substantial morbidity in children and women of reproductive age. The control strategy of mass drug administration is suboptimal, hence…
Source: www.sciencedirect.comCategories: Latest Headlines, PediatricsTweet-
Today @BCM_TropMed @TCHGlobalHealth Vaccine Ctr & outstanding clinical team partners led by @djdiemert #Gabon and #Europe we highlight one of our #hookworm trials in the @TheLancetInfDis. Lots of hard work to advance vaccines against #NTDs. @PeterHotez https://t.co/OExvc5hFH6 https://t.co/EurVfhbVkw
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Mashup Score: 2
Vaccination with recombinant Na-GST-1 and Na-APR-1 (M74) in healthy adults living in N americanus-endemic areas of Gabon was safe and induced IgG to each antigen. To our knowledge, this study is the first to report results of Na-APR-1 (M74) co-administered with Alhydrogel in participants from an N americanus-endemic area. Further clinical development of these vaccines should involve efficacy…
Source: The Lancet Infectious DiseasesCategories: Infectious Disease, Latest HeadlinesTweet-
New research Article: Safety and immunogenicity of co-administered #hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial https://t.co/IoheVJ5g9S
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Mashup Score: 0Hookworm Treatment for Relapsing Multiple Sclerosis - 4 year(s) ago
This randomized clinical trial assesses the effect of hookworm treatment on magnetic resonance imaging activity and T regulatory cells in British patients with relapsing multiple sclerosis.
Source: jamanetwork.comCategories: Latest Headlines, NeurologyTweet-
Study suggests a possible, albeit mild, therapeutic effect of #hookworm infection in relapsing #multiplesclerosis that warrants further study https://t.co/MRVZj8OX5g
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Mashup Score: 4Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps - 4 year(s) ago
Bouchery et al., demonstrate that neutrophils participate in defense against helminth by secreting neutrophil extracellular traps that are toxic to the parasite larvae. In response, the parasite has evolved an evasion strategy based on the secretion of a DNase II that degrades the DNA backbones of the traps.
Source: Cell Host & MicrobeCategories: General Medicine News, Latest HeadlinesTweet-
#Hookworm NET evasion: #neutrophils target #helminth by secreting neutrophil extracellular traps that are toxic to #parasite larvae. However, parasite evades NETs via secreting a DNase II that degrades their DNA backbones @Nicola_L_Harris https://t.co/06RXMlblJN
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Sharing our new @ElsevierConnect #Vaccine Journal article advancing a #hookworm vaccine trial with our @djdiemert Jeff Bethony @BCM_TropMed @PeterHotez https://t.co/sXqKxlMddH