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Mashup Score: 3
CD is strongly associated with GORD but there was high heterogeneity. More convincingly, a GFD substantially improves GORD symptoms, suggesting a role for duodenal inflammation and dietary antigens in the aetiology of a subset with GORD. Ruling out CD in patients with GORD may be beneficial.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0
5-year outcomes confirm the findings of the original RAINBOW trial and a planned interim analysis at 2 years, including a reduced frequency of high myopia following ranibizumab treatment. No effects of treatment on non-ocular outcomes were detected.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0
Treatment with GST-HG171 plus Ritonavir has demonstrated benefits in symptom recovery and viral clearance among low-risk vaccinated adult patients with COVID-19, without apparent safety concerns. As most patients were treated within 2 days after symptom onset in our study, confirming the potential benefits of symptom recovery for patients with a longer duration between symptom onset and treatment initiation will require real-world studies.
Source: www.thelancet.comCategories: General Medicine News, PayerTweet
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Mashup Score: 1Reduced lung function during childhood in identical twins with discordant fetal growth: a cohort study - 5 day(s) ago
Although being genetically identical, sFGR in identical twins is associated with a reduction in static and dynamic lung volume and a reduction in lung diffusion, even when taking the reduced lung volume into account. This indicates that adverse growth conditions in utero negatively affect lung development and function, potentially contributing to an increase in respiratory morbidities later in life.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0
This proof-of-concept study underscores the high potential of harnessing facial images and a tailored XAI approach as an easily accessible alternative over known risk factors for identifying individuals at high risk of skin cancer.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet-
Predicting skin cancer risk from facial images with explainable artificial intelligence (XAI) based approach: a proof-of-concept study XAI approach achieved superior predictive accuracy based on 2D facial images, outperforming that of known risk factors https://t.co/TmPnJVKhBu https://t.co/0wUS2Qxmfe
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Mashup Score: 9eClinicalMedicine, April 2024, Volume 70 - 9 day(s) ago
New general medicine open access journal, published by The Lancet, influencing clinical practice and health policy.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet-
📢 April issue now online featuring #dementia, #obesity, #TB, #lymphoma, #psychosis, #stroke, #mpox, #breastcancer, and much more with our editorial on the Trump presidency and US election …all available #OpenAccess❗️ Read more here: https://t.co/WYYY3eZ1az Attribution: Getty https://t.co/FYEOVV5ecE
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Mashup Score: 1Prevalence of aggressive care among patients with cancer near the end of life: a systematic review and meta-analysis - 10 day(s) ago
This meta-analysis found that aggressive EOL care was common in patients with cancer, regardless of the definition used, and varied by regions and populations. It is necessary to be aware of the global burden of aggressive care for patients with cancer near their EOL and take prompt action to address it.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1Prevalence and determinants of constipation in children in Asia: a systematic review and meta-analysis - 11 day(s) ago
Despite the high heterogeneity resulting from varying diagnostic tools or definitions used among studies, our review adds to the literature on constipation among children in Asia. It reveals a notably high prevalence of constipation in this demographic. Diagnostic methods, age, and compromised mental health emerged as significant influencers of constipation among children in Asia, highlighting potential strategies to mitigate constipation prevalence in children in Asia.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 2
Dexfadrostat phosphate corrected the ARR and aSBP and was well tolerated in patients with PA, demonstrating the benefit of pharmacologically targeting the source of hyperaldosteronism.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1Effect of antipsychotics and mood stabilisers on metabolism in bipolar disorder: a network meta-analysis of randomised-controlled trials - 16 day(s) ago
Our findings suggest that overall, antipsychotics are effective in treating BD, while they are also more likely to disturb metabolism than mood stabilisers. Attention should be paid to individual applicability in clinical practice. The results put forward evidence-based information and clinical inspiration for drug compatibility and further research of the BD mechanism.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
Coeliac disease and risk of Gastro-oesophageal reflux disease: a systematic review and meta-analysis Coeliac disease was strongly associated with GORD, while a gluten-free diet substantially improved GORD symptoms https://t.co/xTsgbZlaDR https://t.co/8NFKxLU0UF