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Mashup Score: 59The Lancet Infectious Diseases, May 2024, Volume 24, Issue 5, Pages 437-556, e268-e343 - 3 day(s) ago
Peruse the current issue of The Lancet Infectious Diseases, a monthly journal covering international issues relevant to clinical infectious diseases specialists worldwide
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Mashup Score: 2
With almost 775 million COVID-19 cases reported worldwide and 67% of the global population vaccinated with a complete primary series of a COVID-19 vaccine, the deadly pace of the pandemic has slowed down substantially.1 Sculpted by infection, immunisation, and subsequent reinfection due to immune escape of antigenically drifted virus variants, the evolving immunity of the population has provided an effective barrier to severe disease for most.2
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Mashup Score: 11
SARS-CoV-2 viral clearance kinetics in symptomatic, vaccinated individuals accelerated substantially over 2 years of the pandemic, necessitating a change to how new SARS-CoV-2 antivirals are compared (ie, shortening the period of pharmacodynamic assessment). As of writing (October, 2023), antiviral efficacy in COVID-19 can be efficiently assessed in vivo using serial qPCRs from duplicate oropharyngeal swab eluates taken daily for 5 days after drug administration.
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 20
In their study in The Lancet Infectious Diseases, Wenting Zuo and colleagues collected tissue samples from 225 patients who had recovered from mild COVID-19 and found that SARS-CoV-2 viral RNA was distributed across ten distinct solid tissues, plasma, and blood cells up to 4 months after infection. Importantly, detection of viral RNA, and higher virus copy numbers, were significantly associated with post-COVID-19 condition (also known as long COVID; odds ratio for association of persistent viral RNA with long COVID symptoms=5·17, 95% CI 2·64–10·13, p<0·0001).
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 130The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China - 4 day(s) ago
Our findings suggest that residual SARS-CoV-2 can persist in patients who have recovered from mild COVID-19 and that there is a significant association between viral persistence and long COVID symptoms. Further research is needed to verify a mechanistic link and identify potential targets to improve long COVID symptoms.
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 128The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China - 4 day(s) ago
Our findings suggest that residual SARS-CoV-2 can persist in patients who have recovered from mild COVID-19 and that there is a significant association between viral persistence and long COVID symptoms. Further research is needed to verify a mechanistic link and identify potential targets to improve long COVID symptoms.
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 108Social histories of public health misinformation and infodemics: case studies of four pandemics - 5 day(s) ago
Recognition of misinformation as a public health threat and interest in infodemics, defined as an inundation of information accompanying an epidemic or acute health event, have increased worldwide. However, scientists have no consensus on how to best define and identify misinformation and other essential characteristics of infodemics. We conducted a narrative review of secondary historical sources to examine previous infodemics in relation to four infectious diseases associated with pandemics (ie, smallpox, cholera, 1918 influenza, and HIV) and challenge the assumption that misinformation is a new phenomenon associated with increased use of social media or with the COVID-19 pandemic.
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 19
In their study in The Lancet Infectious Diseases, Wenting Zuo and colleagues collected tissue samples from 225 patients who had recovered from mild COVID-19 and found that SARS-CoV-2 viral RNA was distributed across ten distinct solid tissues, plasma, and blood cells up to 4 months after infection. Importantly, detection of viral RNA, and higher virus copy numbers, were significantly associated with post-COVID-19 condition (also known as long COVID; odds ratio for association of persistent viral RNA with long COVID symptoms=5·17, 95% CI 2·64–10·13, p<0·0001).
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 128The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China - 5 day(s) ago
Our findings suggest that residual SARS-CoV-2 can persist in patients who have recovered from mild COVID-19 and that there is a significant association between viral persistence and long COVID symptoms. Further research is needed to verify a mechanistic link and identify potential targets to improve long COVID symptoms.
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 103Social histories of public health misinformation and infodemics: case studies of four pandemics - 6 day(s) ago
Recognition of misinformation as a public health threat and interest in infodemics, defined as an inundation of information accompanying an epidemic or acute health event, have increased worldwide. However, scientists have no consensus on how to best define and identify misinformation and other essential characteristics of infodemics. We conducted a narrative review of secondary historical sources to examine previous infodemics in relation to four infectious diseases associated with pandemics (ie, smallpox, cholera, 1918 influenza, and HIV) and challenge the assumption that misinformation is a new phenomenon associated with increased use of social media or with the COVID-19 pandemic.
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
Read our May issue! Featuring switch to oral therapy for bloodstream infection, the public health impact of the R21 malaria vaccine, and preventing malaria in women with HIV https://t.co/wS4e6EplZH https://t.co/jYRRyLE6Os