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Mashup Score: 0Prioritization of genes associated with type 2 diabetes mellitus for functional studies - Nature Reviews Endocrinology - 10 month(s) ago
More genetic variants associated with type 2 diabetes mellitus are being identified. This Perspective article outlines various tools and platforms that can be applied to prioritize candidate genes associated with an increased risk of disease for functional validation.
Source: NatureCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 5
AbstractAims. Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity that is partly explained by the diversity of genetic variants contr
Source: OUP AcademicCategories: Cardiologists, Latest HeadlinesTweet-
🫀The #genetic architecture of #Hypertrophic #cardiomyopathy #HCM in #Egyptian pts: 🧬Minor #Genes could be more relevant than in other populations Congratulations @aguib_y & coll. More 👉https://t.co/1kD2wG2ste @ehj_ed @ESC_Journals @rladeiraslopes @DrMagdiYacoub @ShehabAnwer https://t.co/o0LzAP4lyP
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Mashup Score: 1Effect of Aerobic/Strength Training on RANKL Gene DNA Methylation Levels - 11 month(s) ago
Background: The osteoclastogenesis RANKL gene plays a key role in bone remodeling. The hypomethylation of its promoter region may cause osteoporosis. The present study aimed to elucidate the influence of physical activity on DNA methylation changes of RANKL promoter cytosine-phosphate-guanine (CpG)-rich region in active and sedentary adults and to assess the effect of aerobic and strength…
Source: Human KineticsCategories: Latest Headlines, RheumatologyTweet-
#Exercise can have positive impact on #genes! ✅Increase #DNA methylation of #RANKL ✅Reduce bone loss #Aerobic & #strength exercise also ✅Decrease HR & blood pressure ✅Improve body composition ✅Reduce #BMI & fat 👉🏽https://t.co/RjcnYGNziR via @JPAHjournal #PhysicalActivity https://t.co/qlKlcBEO9h
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Mashup Score: 1Acquired vs. Inherited Mutations in Cancer: What You Need to Know | Dana-Farber Cancer Institute - 11 month(s) ago
Published: April 5, 2023Written by: Beth DoughertyMedically Reviewed By: Anu Chittenden, MS, CGCA gene mutation is a change in the genetic instructions in a cell. Genes are the DNA-encoded instructions for building proteins, which are the machinery that does the work inside our cells and our bodies. Some mutations change the function of proteins in … Read more
Source: Dana-Farber Cancer InstituteCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Dana-Farber Cancer Institute developed one of the first clinical cancer genetics and prevention programs in the world. Learn about how your #genes influence #cancercare and prevention here: https://t.co/pUmqyDqjbq https://t.co/GvFv6QWaDH
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Mashup Score: 0Post-transcriptional control of hemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders - 11 month(s) ago
Abstract. The hemostatic system is pivotal to maintaining vascular integrity. Multiple components involved in blood coagulation have central functions in inflam
Source: OUP AcademicCategories: Cardiology News and Journals, Latest HeadlinesTweet-
Must-read #CardiovascularResearch Review of post-transcriptional control of haemostatic #genes Discover more on mechanisms & emerging therapeutic concepts in thrombo-inflammatory disorders 👉 https://t.co/quzEUgdOft @CVR_TomaszGuzik @DrMikeDrozd @glenpyle #inflammation #sepsis https://t.co/TZC9cf9bBl
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Mashup Score: 8Polygenic prediction of preeclampsia and gestational hypertension - Nature Medicine - 11 month(s) ago
A multi-ancestry genetic meta-analysis identifies 12 new loci associated with preeclampsia and gestational hypertension and proposes the integration of polygenic scores and clinical factors for disease prediction
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
From #genes to gestation, researchers probe predictive markers for #pregnancy complications @NatureMedicine https://t.co/JbKeRIfKoT https://t.co/CivEPIWQDK
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Mashup Score: 1Genetics - PLOS - 12 month(s) ago
Collaborating with researchers from every sub-field, career stage, and demographic to explore, share, and connect the varied complexities of genes and their impact on life in all organisms.
Source: PLOSCategories: Genetics, Latest HeadlinesTweet-
When you choose PLOS Genetics, you join collaborative researchers from every sub-field, career stage, and demographic working to connect the complexities of #Genes and their impact on life in all organisms. Read studies making an impact in your field. 🔎 https://t.co/NBrcRVTcW8 https://t.co/B6dm1lMxpK
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Mashup Score: 3Study: Having Alzheimer's genes may increase your risk of epilepsy - 12 month(s) ago
People with a genetic predisposition for Alzheimer’s disease may have an increased risk of epilepsy and people with a certain type of epilepsy may have an increased risk of developing Alzheimer’s disease, according to a study published in the May 24, 2023, online issue of Neurology.
Source: medicalxpress.comCategories: General Medicine News, Latest HeadlinesTweet-
Study: Having Alzheimer's #genes may increase your risk of #epilepsy https://t.co/JYqEoNlhcX
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Mashup Score: 5Monocyte, neutrophil, and whole blood transcriptome dynamics following ischemic stroke - BMC Medicine - 1 year(s) ago
Background After ischemic stroke (IS), peripheral leukocytes infiltrate the damaged region and modulate the response to injury. Peripheral blood cells display distinctive gene expression signatures post-IS and these transcriptional programs reflect changes in immune responses to IS. Dissecting the temporal dynamics of gene expression after IS improves our understanding of immune and clotting…
Source: BioMed CentralCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
RT @medical_xpress: Researchers identify #genes that can improve #stroke diagnosis and treatment @BMCMedicine https://t.co/aPye1bsoHT https…
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Mashup Score: 9Monocyte, neutrophil, and whole blood transcriptome dynamics following ischemic stroke - BMC Medicine - 1 year(s) ago
Background After ischemic stroke (IS), peripheral leukocytes infiltrate the damaged region and modulate the response to injury. Peripheral blood cells display distinctive gene expression signatures post-IS and these transcriptional programs reflect changes in immune responses to IS. Dissecting the temporal dynamics of gene expression after IS improves our understanding of immune and clotting…
Source: BioMed CentralCategories: General Medicine News, Latest HeadlinesTweet-
Researchers identify #genes that can improve #stroke diagnosis and treatment @BMCMedicine https://t.co/aPye1bsoHT https://t.co/bFCFZxl49b
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In our latest issue, Wei Xuan Tan, Xueling Sim, Chin Meng Khoo & Adrian K. K. Teo discuss prioritization of #genes associated with type 2 #diabetes mellitus for functional studies (£) https://t.co/qMpU3PDpUb #T2DM #T2D https://t.co/fAbD4y00A5