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    Summary Quantitative ethology of social interactions between free-moving animals enables precise measurement of behavioral kinematics critical for various disciplines such as neuroscience. Here, we describe a set of tools for quantitative ethology of social interactions including the analysis pipeline SoAL, the training dataset SDPD, and the camera control software MIAS, along with experimental…

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    • Online in @STARProtocols: Dr. Yi Sun's lab @Yi_Sun_ @Westlake_Uni for quantitative ethology of natural social interactions in #Drosophila: https://t.co/pzY1Ag5uSv Featuring 6 method videos! https://t.co/t2qIHYfTzC

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    Social and Interdisciplinary Sciences Maternal genetic risk for mental illness may cause offspring mental illness and perinatal factors of offspring mental illness. Savanna chimpanzee locomotor and postural behavior supports early hominin bipedalism evolving in the trees, not on the…

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    • For flying insects like #Drosophila, maintaining aerial stability is a constant balancing act. Researchers have identified key roles for two prominent wing steering muscles that fruit flies use to actuate these reflexes. Read more in this week’s issue: https://t.co/zgWQ3UoZlP https://t.co/TxItBcs2Sm

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    Retrotransposons are a class of transposable elements capable of self-replication and insertion into new genomic locations. Across species, the mobilization of retrotransposons in somatic cells has been suggested to contribute to the cell and tissue functional decline that occurs during aging. Retrotransposon expression generally increases with age, and de novo insertions have been observed to…

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    • Expression of #retrotransposons contributes to #aging in #Drosophila https://t.co/gf8tNMXBfQ Fig 3. #Lifespan of ubiquitous shRNA and CRISPRi knockdown of the 683 retrotransposons, 412 and Roo https://t.co/ryrhpcwk5K

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    Author summary The MCM2-7 complex plays a critical role in the DNA replication allowing cells to progress throughout the cell cycle and divide. Overexpression or mutation in MCM2-7 genes is linked to and may drive several cancer types in humans. While MCM2-7 complex is widely expressed in the central nervous system (CNS) during development, its role is not yet clear. Here, we use the CNS of…

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    • Rubio-Ferrera et al identify a highly specific role for a Mcm5 in the specification of the Tv4/FMRFa neuron @biologia_uam @CienciasUAM #Genetics #Drosophila https://t.co/Y7WPAloUM5

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    Author summary A key problem in developmental biology is how species-specific organ size is determined. Control of organ growth occurs at different levels of organization, from the systemic to the cell to cell interaction level. During nervous system development cell contact interactions regulate axon growth. Here, we show that one of the cell adhesion molecules involved in controlling axon…

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    • Velasquez et al show that one of the cell adhesion molecules involved in controlling axon growth also controls epithelial organ growth and size @NeuroAlc @pepegosaelx #Drosophila #Genetics https://t.co/aQh80aGC8Y