-
Mashup Score: 1The Risk of Extraintestinal Cancer in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis of Population-based Cohort Studies - 3 year(s) ago
Patients with Crohn’s disease (CD) and ulcerative colitis (UC) are at increased risk of developing intestinal cancer. However, less is known about the risk of extraintestinal cancers (EICs). The aim of this study was to conduct a systematic review and meta-analysis of population-based cohorts assessing the risk of EICs in inflammatory bowel disease (IBD) patients.
Categories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 1VIDEO: Stelara, Humira safely, effectively treat CD - 3 year(s) ago
Stelara and Humira demonstrated rapid onset of action and effectiveness in the treatment of patients with moderate to severe Crohn’s disease, Bruce Sands, MD, Icahn School of Medicine, told Healio Gastroenterology. In a multicenter, blinded, active-controlled study, researchers randomly assigned 386 biologic-naive patients 1:1 to receive either Stelara (ustekinumab, Janssen) or Humira
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 2Researchers identify biomarkers for infliximab response in pediatric patients with CD - 3 year(s) ago
Researchers identified novel candidate biomarkers for infliximab response after unsupervised plasma proteomic analysis in pediatric patients with Crohn’s disease, according to a presentation at Digestive Disease Week. “For pediatric inflammatory bowel disease, precision medicine is selecting the right drug for the right patient and providing the right dose at the right time. … As
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 0Association of Biomarker Cutoffs and Endoscopic Outcomes in Crohn’s Disease: A Post Hoc Analysis From the CALM Study - 3 year(s) ago
A post hoc analysis of a phase 3 trial in Crohn’s disease showed that a fecal calprotectin cutoff of <250 μg/g accurately classified mucosal healing at week
Source: OUP AcademicCategories: General Medicine News, Latest HeadlinesTweet
-
Mashup Score: 2Ileal or Colonic Histologic Activity Is Not Associated With Clinical Relapse in Patients With Crohn’s Disease in Endoscopic Remission - 3 year(s) ago
Goals of treatment for Crohn’s disease (CD) are clinical and endoscopic remission. It is not clear whether histologic markers of healing associate with endoscopic remission in patients with CD.
Categories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 8DDW® 2021 Virtual - 3 year(s) ago
Centered on Growth
Source: DDW® 2021 VirtualCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 2Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier Integrity in Patients With Crohn’s Disease - 3 year(s) ago
Intestinal epithelial cell (IEC) barrier dysfunction is critical to the development of Crohn’s disease (CD). However, the mechanism is understudied. We recently reported increased microRNA-31-5p (miR-31-5p) expression in colonic IECs of CD patients, but downstream targets and functional consequences are unknown.
Categories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 1
We investigated the effects of inducing deep remission in patients with early Crohn’s disease (CD).
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet-
In analysis of data from the #CALM study, we associated induction of deep #remission in early, moderate to severe #CD with decreased risk of #disease progression over median time of 3 years, regardless of tight control or conventional management strategy. https://t.co/kfPfuPFVFf https://t.co/Svx40QHq6G
-
This Systematic Review and Meta-Analysis shows that both #CD and #UC patients are at an increased risk of developing extraintestinal cancers, both overall and at specific sites https://t.co/hUjUIjp1ys https://t.co/jrsRB3PTxK