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Mashup Score: 1
This study used the database from the Rome Foundation Global Epidemiology Survey to assess the differences in quality of life overall, and by age and sex, across individual disorders of gut-brain interaction (DGBI), gastrointestinal anatomical region(s), and number of overlapping DGBI.
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0
Seroclearance of hepatitis B surface antigen (HBsAg) indicates functional cure for hepatitis B virus (HBV) infection. Low HBsAg levels can predict HBsAg seroclearance over time. However, little is known about the association between hepatitis B core–related antigen (HBcrAg) levels and spontaneous seroclearance of HBsAg.
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0
Colorectal cancer is a leading cause of cancer death, and a major risk factor is chronic inflammation. Despite the link between colitis and cancer, the mechanism by which inflammation leads to colorectal cancer is not well understood.
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1Development and Validation of the TUMMY-UC: A Patient-Reported Outcome for Pediatric Ulcerative Colitis - 2 year(s) ago
The TUMMY-UC is a patient-reported outcome measure for pediatric ulcerative colitis (UC) with an observer-reported outcome version for children aged <8 years. It includes eight items selected by concept elicitation interviews. We aimed to finalize the TUMMY-UC by cognitive interviews (stage 2) and to evaluate the index for its psychometric properties (stage 3).
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0CagA-specific Gastric CD8+ Tissue-Resident T Cells Control Helicobacter pylori During the Early Infection Phase - 2 year(s) ago
A unique population of oligoclonal CD8+ tissue-resident T cells infiltrating the murine and human stomach upon Helicobacter pylori infection is identified, which specifically responds to the bacterial oncogene cytotoxin-associated gene A and mediates pathogen control.
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1Anti-Integrin αvβ6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis - 2 year(s) ago
Better biomarkers for prediction of ulcerative colitis (UC) development and prognostication are needed. Anti-integrin αvβ6 (anti-αvβ6) autoantibodies have been described in patients with UC. We tested for the presence of anti-αvβ6 antibodies in the preclinical phase of UC and studied their association with disease-related outcomes after diagnosis.
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Variation in Testing for and Incidence of Celiac Autoimmunity in Canada: A Population-Based Study - 2 year(s) ago
The incidence of biopsy-confirmed celiac disease has increased. However, few studies have explored the incidence of celiac autoimmunity based on positive serology results.
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Hepatocyte Kctd17 Inhibition Ameliorates Glucose Intolerance and Hepatic Steatosis Caused by Obesity-induced Chrebp Stabilization - 2 year(s) ago
Hepatocyte Kctd17 expression is increased in obesity, which predisposes to insulin resistance and liver fat accumulation. Blocking excess Kctd17 by either genetic or pharmacologic means reverses these pathologic processes, by decreasing Chrebp protein stability, a key factor that regulates both glucose and lipid metabolism.
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 2Post-Colonoscopy Colorectal Cancer Etiologies in a Large Integrated US Health Care Setting - 2 year(s) ago
Colorectal cancer (CRC) is the third most common cancer worldwide.1,2 Screening reduces CRC incidence and mortality through the removal of precancerous lesions and early detection of cancer.2 Although colonoscopy is a high-sensitivity screening method, cancers are sometimes diagnosed after a CRC-negative colonoscopy, a colonoscopy in which cancer was not detected. These post-colonoscopy…
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 0Comparative Performance of Artificial Intelligence Optical Diagnosis Systems for Leaving in Situ Colorectal Polyps - 2 year(s) ago
Screening colonoscopy is effective in reducing colorectal cancer risk but also represents a substantial financial burden.1,2 Novel strategies based on artificial intelligence (AI; computer-aided diagnosis [CADx]) may enable targeted removal only of polyps deemed to be neoplastic, thus reducing patient burden for unnecessary removal of non-neoplastic polyps and reducing costs for…
Source: GastroenterologyCategories: Gastroenterology, Latest HeadlinesTweet
Study provides a representative picture of DGBI impact on adults in the global adult population and highlights the significant detrimental impact of living with a DGBI on quality of life. ➡️ Learn more: https://t.co/AwIO0b5o34 https://t.co/MwfXR2gzNn