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Mashup Score: 1FDA designates recall of troponin tests producing false-negative MI results as class I - 10 month(s) ago
The FDA announced that it has designated a recall of blood tests for cardiac troponin shown to produce false negatives for MI as class I, the most serious kind.On May 25, Quidel Cardiovascular Inc. recalled its cardiac panels (Quidel Triage Cardiac Panel; Quidel Triage Cardiac Panel, Troponin I; and Quidel Triage Cardiac Panel, CK-MB and Troponin I) after it received reports of inaccurate tests
Source: www.healio.comCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
The zebrafish has been established as a genetic and molecular model for the blood-brain barrier.
Source: eLifeCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 5
Background Dementia and frailty are common age-related syndromes often linked to chronic inflammation. Identifying the biological factors and pathways that contribute to chronic inflammation is crucial for developing new therapeutic targets. Circulating cell-free mitochondrial DNA (ccf-mtDNA) has been proposed as an immune stimulator and potential predictor of mortality in acute illnesses….
Source: BioMed CentralCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 10Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD4-selective WNT surrogate in mice - Nature Communications - 11 month(s) ago
The WNT/b-catenin pathway is essential for bloodbrain barrier (BBB) and blood-retina barrier (BRB) function. A bioengineered FZD4-selective WNT surrogate demonstrated systemic efficacy during BRB and ischemic stroke BBB dysfunction in mice.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Stefan Fischli, MD, on Adrenal Function and Perioperative Bleeding - 11 month(s) ago
Study links dHPA and excessive blood loss during surgery
Source: www.medpagetoday.comCategories: General Medicine News, Latest HeadlinesTweet-
ICYMI: Seems like a potentially serious issue for people w/ deficient #hypothalamic-pituitary-adrenal function, w/ coagulation being hampered & the threat of #blood loss increasing. What are the key takeaways? #Endocrinology #ESReadingRoom @TheEndoSociety https://t.co/1tSaVOY2du https://t.co/ye57kF5GoF
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Mashup Score: 12Defining blood-induced microglia functions in neurodegeneration through multiomic profiling - Nature Immunology - 11 month(s) ago
Akassoglou and colleagues provide a single-cell RNA sequencing and phosphoprotein analysis of the responses of central nervous system microglia and macrophages to blood proteins including activated complement and fibrin. Their findings point to potential therapeutic targeting of microglia activation by immune and vascular signals.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0A blood and bronchoalveolar lavage protein signature of rapid FEV1 decline in smoking-associated COPD - Scientific Reports - 11 month(s) ago
Accelerated progression of chronic obstructive pulmonary disease (COPD) is associated with increased risks of hospitalization and death. Prognostic insights into mechanisms and markers of progression could facilitate development of disease-modifying therapies. Although individual biomarkers exhibit some predictive value, performance is modest and their univariate nature limits network-level…
Source: NatureCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 1A blood and bronchoalveolar lavage protein signature of rapid FEV1 decline in smoking-associated COPD - Scientific Reports - 11 month(s) ago
Accelerated progression of chronic obstructive pulmonary disease (COPD) is associated with increased risks of hospitalization and death. Prognostic insights into mechanisms and markers of progression could facilitate development of disease-modifying therapies. Although individual biomarkers exhibit some predictive value, performance is modest and their univariate nature limits network-level…
Source: NatureCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 23Eye Blood Vessel Changes: A New Window into Alzheimer's Diagnosis - Neuroscience News - 12 month(s) ago
Abnormalities in eye blood vessels could provide early diagnosis of Alzheimer’s disease.
Source: Neuroscience NewsCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 4The contribution of the exposome to the burden of cardiovascular disease - Nature Reviews Cardiology - 12 month(s) ago
In this Review, Münzel and colleagues describe the exposome concept with a focus on environmental physical and chemical exposures and their effects on the burden of cardiovascular disease. Additionally, they discuss selected exposome studies and the relevance of the exposome concept for future health research and preventive medicine.
Source: NatureCategories: Healthcare Professionals, Latest HeadlinesTweet
The #FDA designated a recall of #blood tests for cardiac #troponin due to the risk for false negative or falsely low levels for #MI. https://t.co/wmKEyu4Qlz