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    The availability of biologic agents for patients with severe asthma has increased dramatically over the last several decades. The absence of direct head-to-head comparative data and relative lack of biomarkers to predict response can make it difficult to choose the right biologic medication for a given patient. Selecting a biologic agent for the pediatric population presents further challenges due to more limited approved biologic agents and fewer clinical trials in children. In addition, the outcome data that are currently available suggest that treatment responses for a given biologic may be different between adult and pediatric patients.

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    Consuming at least 20% of daily calories from fast food correlated with an increased risk for nonalcoholic fatty liver disease, with more damaging effects among individuals with underlying metabolic comorbidities. “Fast food consumption has been linked to diabetes and obesity, but there is very little clinical or population-based data on how eating fast foods impact the risk of fatty liver,

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    Management of asthma in adults has advanced in the past 10 years. Central to these advances has been further clarification of type (T) 2 mechanisms of airway inflammation and utilization of T2 biomarkers, that is, eosinophils and fractional exhaled nitric oxide. In addition, epithelial cells are emerging as significant contributors to inflammation through generation of alarmins to initiate local…

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