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    The evolving view of thermogenic adipocytes — ontogeny, niche and function - Nature Reviews Endocrinology - 2 year(s) ago

    This Review highlights the ontogeny of thermogenic adipocytes, regulation of the adipose tissue microenvironment and inter-organ communication between adipose and other tissues. In addition, activation of thermogenic adipose tissue in humans and animal models is discussed, as well as the therapeutic potential of thermogenic adipose tissue.

    Source: Nature
    Categories: Endocrinology, Latest Headlines
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      NatureRevEndo

      This Review by Yu-Hua Tseng and colleagues discusses the thermogenic function of brown and beige #adipocytes and the potential therapeutic applications of these cells in treating #obesity https://t.co/3J0jOVUWsH https://t.co/9NldD7CgZB

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    The evolving view of thermogenic adipocytes — ontogeny, niche and function - Nature Reviews Endocrinology - 2 year(s) ago

    This Review highlights the ontogeny of thermogenic adipocytes, regulation of the adipose tissue microenvironment and inter-organ communication between adipose and other tissues. In addition, activation of thermogenic adipose tissue in humans and animal models is discussed, as well as the therapeutic potential of thermogenic adipose tissue.

    Source: Nature
    Categories: Endocrinology, Latest Headlines
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      NatureRevEndo

      Farnaz Shamsi, Chih-Hao Wang & Yu-Hua Tseng discuss the ontogeny of thermogenic #adipocytes, regulation of the #adipose tissue microenvironment and inter-organ communication between adipose and other tissues (£) https://t.co/fK22pvuOpB https://t.co/OOR3HSbc2h

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    Nature Reviews Endocrinology - 2 year(s) ago

    Nature Reviews Endocrinology is a peer-reviewed journal for endocrinologists and affiliated healthcare professionals. The journal delivers timely …

    Source: Nature Reviews Endocrinology
    Categories: Endocrinology, Latest Headlines
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      NatureRevEndo

      The @NatureRevEndo December issue is now live! Includes articles on the #insulin centenary, #adipocytes, melanin-concentrating hormone and paracetamol -> https://t.co/Atja3RzWdE https://t.co/3D8xcsWNnh

  • Mashup Score: 5
    A protocol for human bone marrow adipocyte isolation and purification: STAR Protocols - 3 year(s) ago

    Summary Primary human bone marrow adipocytes (BM-Ads) display a specific metabolism that is not recapitulated by in vitro differentiated bone marrow mesenchymal stromal cells. These findings highlight the need for using primary BM-Ads in studies of the metabolic impact of BM-Ads on surrounding cells. Here, we present a protocol for isolating human BM-Ads from bone…

    Source: star-protocols.cell.com
    Categories: General Medicine News, Latest Headlines
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      CellPressNews

      Online in @STARProtocols: Dr. Catherine Muller's lab @AdipoKToulouse @AttaneC @IpbsToulouse, describing the isolation and purification of human bone marrow #adipocytes https://t.co/t2v4Ait6WE https://t.co/YJsFRghLDK

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    Iron in adipocytes — a role in gut–adipose crosstalk - 3 year(s) ago

    Iron levels are known to be associated with type 2 diabetes mellitus (T2DM), with high levels of iron leading to an increased risk of T2DM and iron levels in adipocytes seemingly being involved. However, the mechanisms underlying the role of iron in the pathogenesis of T2DM and its function in adipose tissue have been unclear. New work by Philipp Scherer and colleagues answers some of these…

    Source: Nature Reviews Endocrinology
    Categories: Endocrinology, Latest Headlines
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      NatureRevEndo

      Online now: a new #ResearchHighlight discusses the role of iron in #adipocytes in facilitating gut-adipose communication (£) https://t.co/XGyw9mgUWv https://t.co/OkhTFmFebt

  • Mashup Score: 8
    The cellular and functional complexity of thermogenic fat - 3 year(s) ago

    Brown and beige adipocytes are mammalian thermogenic fat cells that regulate whole-body energy metabolism. Notably, brown/beige adipocytes are heterogeneous and their functions extend beyond thermogenesis, encompassing roles as metabolite sinks, as secretory cells and as regulators of adipose tissue homeostasis. Thus, induction of brown/beige fat activity correlates with improved metabolic health.

    Source: Nature Reviews Molecular Cell Biology
    Categories: Allergy-Immunology, Latest Headlines
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      NatRevMCB

      In June issue A hot #Review (no pun intended!) by Kajimura&Cohen on the mechanisms of thermogenic fat #BrownAdiposeTissue #Thermogenesis #Adipocytes #Adipogenesis @RockefellerUniv @skajimura @harvardmed https://t.co/VQyY979HF6 FREE online pdf: https://t.co/JCDXjShi2t #sharedit https://t.co/p1dMb21Hky

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    Identification of thermogenic adipocyte lineages - 3 year(s) ago

    Access options Subscribe to JournalGet full journal access for 1 year$59.00only $4.92 per issueAll prices are NET prices. VAT will be added later in the checkout.Tax calculation will be finalised during…

    Source: Nature Reviews Endocrinology
    Categories: Endocrinology, Latest Headlines
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      NatureRevEndo

      AOP #ResearchHighlight - discussion of two papers investigating the lineages of thermogenic #adipocytes (£) https://t.co/bt9f2UJ6fO @PennIDOM @FarnazShamsi @MatthewDLynes @tsengyuhua @JoslinDiabetes https://t.co/JX8LV0JVhv

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