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Mashup Score: 0
Pertussis vaccination at three different time intervals in pregnancy resulted in equivalent concentrations of IgG antibodies in infants against two of the three pertussis antigens assessed. Overall, these findings support recommendations to vaccinate any time between 16 weeks and 32 weeks of gestation.
Source: The Lancet MicrobeCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 3Spatiotemporal dynamics and recurrence of chikungunya virus in Brazil: an epidemiological study - 2 year(s) ago
Spatial heterogeneity of CHIKV spread and population immunity might explain the recurrence pattern of chikungunya in Brazil. These results can be used to inform public health interventions to prevent future chikungunya epidemic waves in urban settings.
Source: The Lancet MicrobeCategories: Infectious Disease, Latest HeadlinesTweet-
Spatiotemperal dynamics analysis showing Chikungunya epidemics in Brazil are driven by population immunity and new lineage intro’s https://t.co/N79LrXbz3h remarkable: the cited death rate, quite high. Most likely reflects underascertainment as is common for arbovirus infections https://t.co/LdFA4xGgop
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Mashup Score: 5Risk factors and vectors for SARS-CoV-2 household transmission: a prospective, longitudinal cohort study - 2 year(s) ago
Presence of SARS-CoV-2 RNA on primary cases’ and contacts’ hands and on frequently-touched household surfaces associates with transmission, identifying these as potential vectors for spread in households.
Source: The Lancet MicrobeCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 91Risk factors and vectors for SARS-CoV-2 household transmission: a prospective, longitudinal cohort study - 2 year(s) ago
Presence of SARS-CoV-2 RNA on primary cases’ and contacts’ hands and on frequently-touched household surfaces associates with transmission, identifying these as potential vectors for spread in households.
Source: The Lancet MicrobeCategories: Expert Picks, Latest HeadlinesTweet
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Mashup Score: 0
The efficacy of SARS-CoV-2 vaccines is higher for preventing severe infection and death than for preventing milder infection. Vaccine efficacy wanes over time but can be enhanced by a booster. Higher antibody titres are associated with higher estimates of efficacy but precise predictions are difficult due to large unexplained heterogeneity. These findings provide an important knowledge base for…
Source: The Lancet MicrobeCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 5Mpox respiratory transmission: the state of the evidence - 2 year(s) ago
The relative contribution of the respiratory route to transmission of mpox (formerly known as monkeypox) is unclear. We review the evidence for respiratory transmission of monkeypox virus (MPXV), examining key works from animal models, human outbreaks and case reports, and environmental studies. Laboratory experiments have initiated MPXV infection in animals via respiratory routes. Some…
Source: The Lancet MicrobeCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 121
The efficacy of SARS-CoV-2 vaccines is higher for preventing severe infection and death than for preventing milder infection. Vaccine efficacy wanes over time but can be enhanced by a booster. Higher antibody titres are associated with higher estimates of efficacy but precise predictions are difficult due to large unexplained heterogeneity. These findings provide an important knowledge base for…
Source: The Lancet MicrobeCategories: Expert Picks, Latest HeadlinesTweet-
A systematic review of all of the 28 Covid vaccine randomized trials vs placebo Protection from hospitalization 94% Protection from death 86% https://t.co/tqEvDLBOqq "insufficiently efficacious in preventing infections and therefore cannot stop the pandemic alone" @LancetMicrobe https://t.co/YR2iv5TEO0
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Mashup Score: 15Antigenic mapping of emerging SARS-CoV-2 omicron variants BM.1.1.1, BQ.1.1, and XBB.1 - 2 year(s) ago
Novel SARS-CoV-2 omicron variants, including BM.1.1.1, BQ.1.1, and XBB.1, continue to emerge at an unprecedented rate, evading pre-existing immunity from vaccination and previous infection. Quantifying the antigenic diversity of variants might assist in selecting future vaccine strains. To determine the antigenic relationships between emerging SARS-CoV-2 omicron variants, we and others1–4 used…
Source: The Lancet MicrobeCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 20Antigenic mapping of emerging SARS-CoV-2 omicron variants BM.1.1.1, BQ.1.1, and XBB.1 - 2 year(s) ago
Novel SARS-CoV-2 omicron variants, including BM.1.1.1, BQ.1.1, and XBB.1, continue to emerge at an unprecedented rate, evading pre-existing immunity from vaccination and previous infection. Quantifying the antigenic diversity of variants might assist in selecting future vaccine strains. To determine the antigenic relationships between emerging SARS-CoV-2 omicron variants, we and others1–4 used…
Source: The Lancet MicrobeCategories: Expert Picks, Latest HeadlinesTweet-
Mapping XBB.1's antigenic distance (among others): "We observed that human post-vaccination neutralisation titres reflected the antigenic map, as the largest reduction in neutralising titres compared with the D614G variant" https://t.co/epa5txNqqw @LancetMicrobe @bart_haagmans https://t.co/oEIeUKt8HR
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Mashup Score: 1
Previous natural infection was associated with lower incidence of SARS-CoV-2 infection, regardless of the variant, than mRNA primary-series vaccination. Vaccination remains the safest and most optimal tool for protecting against infection and COVID-19-related hospitalisation and death, irrespective of previous infection status.
Source: The Lancet MicrobeCategories: Cardiologists, Latest HeadlinesTweet
Optimising the timing of whooping cough immunisation in mums (OpTIMUM) through investigating pertussis vaccination in pregnancy https://t.co/yke130QIsh