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Mashup Score: 23Synthetic soldiers: Turning T cells into immortal warriors | Journal of Experimental Medicine | Rockefeller University Press - 12 day(s) ago
The creation of synthetic T cell states has captivated the field of cell-based therapies. Wang et al. describe how disruption of BCOR and ZC3H12A unleashes
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Mashup Score: 267
SARS-CoV-2 cell tropism and infection cycle are defined at the cellular resolution by infection of healthy human lung tissue and single-cell profiling. Int
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Mashup Score: 1
Piezo1 channels regulate the magnitude of ILC2-dependent type 2 lung inflammation. In murine and human ILC2s, Piezo1 channels are induced by allergen and c
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Mashup Score: 3Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity | Journal of Experimental Medicine | Rockefeller University Press - 1 month(s) ago
Piezo1 channels regulate the magnitude of ILC2-dependent type 2 lung inflammation. In murine and human ILC2s, Piezo1 channels are induced by allergen and c
Source: rupress.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 2Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity | Journal of Experimental Medicine | Rockefeller University Press - 1 month(s) ago
Piezo1 channels regulate the magnitude of ILC2-dependent type 2 lung inflammation. In murine and human ILC2s, Piezo1 channels are induced by allergen and c
Source: rupress.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 2A TNF-IL-1 circuit controls Yersinia within intestinal pyogranulomas - 2 month(s) ago
Monocytes restrict Yersinia infection within intestinal pyogranulomas. Here, we report that monocyte-intrinsic TNF signaling drives the production of IL-1 that
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Mashup Score: 0Leukotriene B4 amplifies eosinophil accumulation in response to nematodes | Journal of Experimental Medicine | Rockefeller University Press - 3 month(s) ago
Rapid eosinophil accumulation around nematode species occurs via leukotriene induction, which is necessary for nematode-induced eosinophil accumulation in the l
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Mashup Score: 0The effector program of human CD8 T cells supports tissue remodeling | Journal of Experimental Medicine | Rockefeller University Press - 3 month(s) ago
This work reveals that human effector CD8 T cells not only mediate cytotoxicity but also promote tissue remodeling. The remodeling potential was demonstrated in
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Mashup Score: 26The effector program of human CD8 T cells supports tissue remodeling | Journal of Experimental Medicine | Rockefeller University Press - 4 month(s) ago
This work reveals that human effector CD8 T cells not only mediate cytotoxicity but also promote tissue remodeling. The remodeling potential was demonstrated in
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Mashup Score: 95
A preclinical mouse model demonstrates that genetic alterations in the blood system characteristic of clonal hematopoiesis (CH) contribute to an aggressive soli
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