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    Genome-wide association studies (GWAS) aim to identify common genetic variants that are associated with traits and diseases. Since 2005, more than 5,000 GWAS have been published for almost as many traits. These studies have offered insights into the loci and genes underlying phenotypic traits, highlighted genetic correlations across traits and diseases and are beginning to demonstrate clinical…

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    “Frailty” is a term used to refer to a state characterised by enhanced vulnerability to, and impaired recovery from, stressors, when compared to a non-frail state, which is increasingly viewed as a loss of resilience. With increasing life expectancy and the associated rise in years spent with physical frailty, there is a need to understand the clinical and physiological features of frailty and…

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    • #Inflammation is associated with #frailty ✅#Exercise can reduce & reverse frailty Need to understand clinical & physiological features of frailty ➡️Adiposity ➡️Brain ➡️Neuromuscular ➡️Skeletal muscle ➡️Immune ➡️Cardiovascular systems 👉🏽https://t.co/lxwAT85nKX via @physiolrev https://t.co/zUOt1OLes2