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Mashup Score: 0Single-cell omics - 7 month(s) ago
Many biological phenomena are either invisible or only partially characterized when interrogated using standard analyses that average data across a bulk …
Source: NatureCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 4
This Evidence-Based Guideline presents the latest treatment recommendations for medication selection in psoriatic arthritis (PsA), covering the six clinical domains of PsA, related conditions and associated comorbidities, and reflecting important advances in the field since the previous update.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
In honour of #WorldArthritisDay, we’re sharing some of our content to raise awareness Check out GRAPPA treatment recommendations for psoriatic #arthritis #free to access at: https://t.co/SIBpalt1jR #WAD2023 https://t.co/vimQPBVABB
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Mashup Score: 2Nature Reviews Endocrinology - 7 month(s) ago
Nature Reviews Endocrinology is a peer-reviewed journal for endocrinologists and affiliated healthcare professionals. The journal delivers timely …
Source: NatureCategories: Endocrinology, Latest HeadlinesTweet-
The @NatureRevEndo November issue is now live! Including articles on #bone marrow #adipose, neurobiological tools, weight regain, #pituitary neoplasms and more -> https://t.co/Atja3RzWdE https://t.co/Nozpr4awl8
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Mashup Score: 0Targeting pancreatic cancer metabolic dependencies through glutamine antagonism - Nature Cancer - 7 month(s) ago
Kimmelman and colleagues show that inhibition of glutamine (Gln) metabolism using a Gln antagonist decreases pancreatic cancer tumor growth, but is compensated by upregulation of extracellular signal-regulated kinase signaling, which can be co-targeted.
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
💫NEW CONENT @NatureCancer "Targeting pancreatic cancer metabolic dependencies through glutamine antagonism” by #AlecMKimmelman & Co. Read it here 👇 https://t.co/euhuYH9hYr https://t.co/VLqxZJ3BJX
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Mashup Score: 3
Liebers and colleagues present a prospective non-interventional trial in 80 individuals with hematologic cancer investigating the potential of ex vivo drug response profiling and show it to be clinically feasible.
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
💫ONLINE NOW @NatureCancer “ Ex vivo drug response profiling for response and outcome prediction in hematologic malignancies: the prospective non-interventional SMARTrial” by @DietrichLab & Co. #leukemia #lymphoma👇 https://t.co/kmqx8sL8BJ https://t.co/qjJeHSpjsJ https://t.co/SWulypkW7z
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Mashup Score: 1Illuminating the human yolk sac through single-cell omics - Nature Reviews Immunology - 7 month(s) ago
A paper in Science reports a time-resolved multiomic atlas of the human yolk sac, shedding light on macrophage differentiation pathways.
Source: NatureCategories: Allergy-Immunology, Latest HeadlinesTweet-
NEW Highlight of @ScienceMagazine paper by @IssacEGoh @Muzz_Haniffa @HaniffaLab @teichlab that reports a time-resolved multiomic atlas of the human yolk sac, shedding light on macrophage differentiation pathways https://t.co/VylAHj4S4J https://t.co/XsbXfSMQls
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Mashup Score: 1Hepatic inflammatory responses in liver fibrosis - Nature Reviews Gastroenterology & Hepatology - 7 month(s) ago
Liver inflammation is a key process that orchestrates intrahepatic injury. This Review offers a comprehensive overview of the inflammatory mechanisms of hepatic fibrosis and discusses current advances and therapeutic implications.
Source: NatureCategories: Gastroenterology, Latest HeadlinesTweet-
2/5 🧵FREE to read until Oct 26: "Hepatic inflammatory responses in liver fibrosis" #Review | Read here: https://t.co/VwR7jXlIGj
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Mashup Score: 1Friend or foe? The elusive role of hepatic stellate cells in liver cancer - Nature Reviews Gastroenterology & Hepatology - 7 month(s) ago
Hepatic stellate cells (HSCs) drive liver fibrosis and are closely linked to liver cancer development. This comprehensive Review provides an in-depth analysis of the specific characteristics of HSCs in cancer, highlighting therapeutic implications based on progress in clarifying HSC biology.
Source: NatureCategories: Gastroenterology, Latest HeadlinesTweet-
3/5 🧵FREE to read until Oct 26: "Friend or foe? The elusive role of hepatic stellate cells in liver cancer" #Review | Read here: https://t.co/M5YIVv6joW
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Mashup Score: 1Cellular stress in the pathogenesis of nonalcoholic steatohepatitis and liver fibrosis - Nature Reviews Gastroenterology & Hepatology - 7 month(s) ago
Increasing evidence shows a role of cellular stress responses in nonalcoholic steatohepatitis (NASH) and liver fibrosis pathogenesis. This Review provides a comprehensive overview of the molecular mechanisms involved in cellular stress in fibrogenesis and their role in NASH progression.
Source: NatureCategories: Gastroenterology, Latest HeadlinesTweet-
4/5 🧵FREE to read until Oct 26: "Cellular stress in the pathogenesis of nonalcoholic steatohepatitis and liver fibrosis" #Review | Read here: https://t.co/6Y7pPRzoe1
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Mashup Score: 2Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approach - Nature Reviews Gastroenterology & Hepatology - 7 month(s) ago
Tackling fibrosis in patients with nonalcoholic steatohepatitis (NASH), one of the major causes of liver cirrhosis, is critical in improving patient outcomes. This Perspective discusses potential strategies to develop better antifibrotic therapies in NASH, from the discovery process to future clinical trials.
Source: NatureCategories: Gastroenterology, Latest HeadlinesTweet-
5/5 🧵FREE to read until Oct 26: "Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approach" a Perspective | Read here: https://t.co/8e6R3V16bA
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This review is part of a wider Focus collection on single-cell omics, which highlights the exciting developments in this field and the transformative potential of single-cell omics technologies: https://t.co/9NpRw8qvOE