• Mashup Score: 9
    Retroviruses of Bats: a Threat Waiting in the Wings? | mBio - 3 year(s) ago

    Bats are infamous reservoirs of deadly human viruses. While retroviruses, such as human immunodeficiency virus (HIV), are among the most significant of virus families that have jumped from animals into humans, whether bat retroviruses have the potential …

    Source: mBio
    Categories: Infectious Disease, Latest Headlines
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      Amy_Kullas

      RT @ASMicrobiology: New minireview in @mBioJournal: Retroviruses of Bats: a Threat Waiting in the Wings? https://t.co/gVBnAA9wwl https://t.…

  • Mashup Score: 3
    A Widespread Bacterial Secretion System with Diverse Substrates | mBio - 3 year(s) ago

    In host-associated bacteria, surface and secreted proteins mediate acquisition of nutrients, interactions with host cells, and specificity of tissue localization. In Gram-negative bacteria, the mechanism by which many proteins cross and/or become tethered to the outer membrane remains unclear. The domain of unknown function 560 (DUF560) occurs in outer membrane proteins throughout Proteobacteria…

    Source: mBio
    Categories: Infectious Disease, Latest Headlines
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      Amy_Kullas

      RT @AsafLevyHUJI: The bacterial type 11 secretion system (TXISS) ?? https://t.co/ZzgXOL2QjS The TXISS genes affect bacterial colonization o…

  • Mashup Score: 30
    Recovery from Acute SARS-CoV-2 Infection and Development of Anamnestic Immune Responses in T Cell-Depleted Rhesus Macaques | mBio - 3 year(s) ago

    Severe coronavirus disease 2019 (COVID-19) has been associated with T cell lymphopenia, but no causal effect of T cell deficiency on disease severity has been established. To investigate the specific role of T cells in recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we studied rhesus macaques that were depleted of either CD4+, CD8+, or both T cell subsets…

    Source: mBio
    Categories: Infectious Disease, Latest Headlines
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    • Profile photo of infdisease_news
      infdisease_news

      To investigate the specific role of T cells in recovery from #SARS-CoV-2 infections, researchers studied rhesus macaques that were depleted of either CD4+, CD8+, or both T cell subsets prior to #infection. https://t.co/VSH3LFVeOb https://t.co/hsOdkRxeci

  • Mashup Score: 34
    Recovery from Acute SARS-CoV-2 Infection and Development of Anamnestic Immune Responses in T Cell-Depleted Rhesus Macaques | mBio - 3 year(s) ago

    Severe coronavirus disease 2019 (COVID-19) has been associated with T cell lymphopenia, but no causal effect of T cell deficiency on disease severity has been established. To investigate the specific role of T cells in recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we studied rhesus macaques that were depleted of either CD4+, CD8+, or both T cell subsets…

    Source: mBio
    Categories: Cardiologists, Latest Headlines
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    • Profile photo of EricTopol
      EricTopol

      Yet another new report that undermines the T cell narrative for its role in defense against #SARSCoV2 reinfection, an experimental depletion study in macaques https://t.co/H41tqcpUQr @mbiojournal https://t.co/EsGinV6hyf https://t.co/tGpqBNrVOR

  • Mashup Score: 2
    Trade-off between Plasticity and Velocity in Mycelial Growth | mBio - 3 year(s) ago

    Tip-growing fungal cells maintain cell polarity at the apical regions and elongate by de novo synthesis of the cell wall. Cell polarity and tip growth rate affect mycelial morphology. However, it remains unclear how both features act cooperatively to determine cell shape. Here, we investigated this relationship by analyzing hyphal tip growth of filamentous fungi growing inside extremely narrow…

    Source: mBio
    Categories: Hem/Oncs, Latest Headlines
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      cancerassassin1

      These appear to be a fungal version of #TunnelingNanotubes, but they are not designated as such in this paper published in @mbiojournal. The paper is very interesting - lots of learning that can be translated to mammalian cell protrusions. https://t.co/Cz0V0d4aXh https://t.co/BNGQyTofrj https://t.co/LYQlAIUzDP

  • Mashup Score: 9
    Moratorium on Research Intended To Create Novel Potential Pandemic Pathogens - 3 year(s) ago

    The views expressed in this article do not necessarily reflect the views of the journal or of ASM. Research on highly pathogenic organisms is crucial for medicine and public health, and we strongly support it. This work creates a foundation of new knowledge that provides critical insights around the world’s most deadly infectious diseases, and it can lay groundwork for the future development of…

    Source: mBio
    Categories: Infectious Disease, Latest Headlines
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    • Profile photo of mlipsitch
      mlipsitch

      Some members of @cambridgeWG may categorically oppose all GOF studies that enhance virulence, transmission, or immune escape. My personal view is that some such studies can be justified on risk-benefit grounds, while those on flu to date cannot https://t.co/0YhR6UKuCn

  • Mashup Score: 0
    What Is the Price of Science? - 3 year(s) ago

    The peer-reviewed scientific literature is the bedrock of science. However, scientific publishing is undergoing dramatic changes, which include the expansion of open access, an increased number of for-profit publication houses, and ready availability of preprint manuscripts that have not been peer reviewed. In this opinion article, we discuss the inequities and concerns that these changes have…

    Source: mBio
    Categories: Hem/Oncs, Latest Headlines
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    • Profile photo of sghmd
      sghmd

      All of this 👇 https://t.co/PqIrEwOhl3

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