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Mashup Score: 0Nutritional risk factors for SARS-CoV-2 infection: a prospective study within the NutriNet-Santé cohort - BMC Medicine - 2 year(s) ago
Background Nutritional factors are essential for the functioning of the immune system and could therefore play a role in COVID-19 but evidence is needed. Our objective was to study the associations between diet and the risk of SARS-CoV-2 infection in a large population-based sample. Methods Our analyses were conducted in the French prospective NutriNet-Santé cohort study (2009–2020)….
Source: BMC MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0
Background In order to understand the intricate patterns of interplay connected to the formation and maintenance of depressive symptomatology, repeated measures investigations focusing on within-person relationships between psychopathological mechanisms and depressive components are required. Methods This large-scale preregistered intensive longitudinal study conducted 68,240 observations of 1706…
Source: BMC MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Helplessness is an important mechanistic variable in the maintenance and change of depressive symptoms in the general population during the COVID-19 pandemic, reports research published in @BMCMedicine. https://t.co/wO6gRgT4Wx
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Mashup Score: 0
Background Chronic kidney disease (CKD) typically co-exists with multimorbidity (presence of 2 or more long-term conditions: LTCs). The associations between CKD, multimorbidity and hospitalisation rates are not known. The aim of this study was to examine hospitalisation rates in people with multimorbidity with and without CKD. Amongst people with CKD, the aim was to identify risk factors for…
Source: BMC MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Among people with multimorbidities, the rates of hospitalisation are two to three times higher when chronic kidney disease is one of the multimorbid conditions. https://t.co/n8q81VYxkI
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Mashup Score: 0Antibody conversion rates to SARS-CoV-2 in saliva from children attending summer schools in Barcelona, Spain - BMC Medicine - 2 year(s) ago
Background Surveillance tools to estimate viral transmission dynamics in young populations are essential to guide recommendations for school opening and management during viral epidemics. Ideally, sensitive techniques are required to detect low viral load exposures among asymptomatic children. We aimed to estimate SARS-CoV-2 infection rates in children and adult populations in a school-like…
Source: BMC MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Antibody profiling in saliva samples is a helpful and simpler tool to determine the prevalence of SARS-CoV-2 exposure in pediatric populations, according to a study published in @BMCMedicine. https://t.co/pL9fGnCpsT
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Mashup Score: 2Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine - BMC Medicine - 2 year(s) ago
Background There is a clear need for novel approaches to malaria vaccine development. We aimed to develop a genetically attenuated blood-stage vaccine and test its safety, infectivity, and immunogenicity in healthy volunteers. Our approach was to target the gene encoding the knob-associated histidine-rich protein (KAHRP), which is responsible for the assembly of knob structures at the infected…
Source: BMC MedicineCategories: Infectious Disease, Latest HeadlinesTweet-
A new study led by Dr. James McCarthy at @QIMRBerghofer represents the first clinical investigation of a genetically attenuated blood-stage human #MalariaVaccine. 💉 @BMCMedicine | https://t.co/0y1rsAmnPo https://t.co/9VTpmQrC02
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Mashup Score: 14
Background By August 2021, the COVID-19 pandemic has been less severe in sub-Saharan Africa than elsewhere. In Malawi, there have been three subsequent epidemic waves. We therefore aimed to describe the dynamics of SARS-CoV-2 exposure in Malawi. Methods We measured the seroprevalence of anti-SARS-CoV-2 antibodies amongst randomly selected blood transfusion donor sera in Malawi from January 2020…
Source: BMC MedicineCategories: Infectious Disease, Latest HeadlinesTweet-
RT @lemoncul: Our paper about SARS-CoV-2 seroprevalence in Malawi is out in BMC Medicine: https://t.co/EOHgXSD8Ko Summary: extremely high n…
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Mashup Score: 1Risk of bias in observational studies using routinely collected data of comparative effectiveness research: a meta-research study - BMC Medicine - 2 year(s) ago
Background To assess the completeness of reporting, research transparency practices, and risk of selection and immortal bias in observational studies using routinely collected data for comparative effectiveness research. Method We performed a meta-research study by searching PubMed for comparative effectiveness observational studies evaluating therapeutic interventions using routinely collected…
Source: BMC MedicineCategories: Cardiologists, Latest HeadlinesTweet-
Risk of bias in observational studies using routine data for comparative effectiveness research: a meta-research study. 8% of studies raised concerns re. unclear reporting. 25% were at high risk of selection bias and/or immortal time bias. https://t.co/Wt9VQ6GZan https://t.co/5MYjsIis50
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Mashup Score: 0
Background Chronic kidney disease (CKD) typically co-exists with multimorbidity (presence of 2 or more long-term conditions: LTCs). The associations between CKD, multimorbidity and hospitalisation rates are not known. The aim of this study was to examine hospitalisation rates in people with multimorbidity with and without CKD. Amongst people with CKD, the aim was to identify risk factors for…
Source: BMC MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Among people with multimorbidities, the rates of hospitalisation are two to three times higher when chronic kidney disease is one of the multimorbid conditions. https://t.co/QywKT1OntB
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Mashup Score: 2Computer-assisted quantification of tumor-associated collagen signatures to improve the prognosis prediction of breast cancer - BMC Medicine - 2 year(s) ago
Background Collagen fibers play an important role in tumor initiation, progression, and invasion. Our previous research has already shown that large-scale tumor-associated collagen signatures (TACS) are powerful prognostic biomarkers independent of clinicopathological factors in invasive breast cancer. However, they are observed on a macroscale and are more suitable for identifying high-risk…
Source: BMC MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Computer-associated quantification of #tumor associated #collagen signatures to improve prognosis prediction of #breastcancer Read it here: https://t.co/s708V2wXKD https://t.co/0IJDS0jwn4
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Mashup Score: 0COVID-19 and risk of subsequent life-threatening secondary infections: a matched cohort study in UK Biobank - BMC Medicine - 2 year(s) ago
Background With the increasing number of people infected with and recovered from coronavirus disease 2019 (COVID-19), the extent of major health consequences of COVID-19 is unclear, including risks of severe secondary infections. Methods Based on 445,845 UK Biobank participants registered in England, we conducted a matched cohort study where 5151 individuals with a positive test result or…
Source: BMC MedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Risk of subsequent life-threatening secondary #infections associated with #COVID19 in the #UKBiobank Read it here: https://t.co/YfnbuemmTS https://t.co/teanwgikbw
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Research published in @BMCMedicine reveals that higher dietary intakes of fruit and vegetables, vitamin C, folate, vitamin K and fibers are associated with lower susceptibility to SARS-CoV-2 infection. https://t.co/iL8l8XzDg4