The American Journal of Human Genetics: Cell Press
AJHG publishes peer-reviewed research articles relating to heredity in humans and the application of genetic principles in medicine and public policy.
AJHG publishes peer-reviewed research articles relating to heredity in humans and the application of genetic principles in medicine and public policy.
Constance Jean (Connie) Eaves was a pioneering scientist with outstanding and consistent contributions throughout her long-spanning, fifty-plus-year career. Her work with over 500 publications in hematopoiesis…
Advances in biomedical research require a robust physician scientist workforce. Despite being equally successful at securing early career awards from the NIH as men, women…
Advances in biomedical research require a robust physician scientist workforce. Despite being equally successful at securing early career awards from the NIH as men, women…
Advances in biomedical research require a robust physician scientist workforce. Despite being equally successful at securing early career awards from the NIH as men, women…
Adult humans with inherited, complete FLT3L deficiency enable valuable insights into the role of the hematopoietic growth factor FLT3L in human hematopoiesis, revealing that FLT3L…
Despite the relative noisiness of polygenic indexes (PGIs), some commercial firms will use them. We offer a simple model, rooted in economic theory, to show…
To accelerate CRISPR-based targeting of RNA, Guo et al. present a resource with optimized RfxCas13d guide RNAs (gRNAs) to target messenger RNAs and noncoding RNAs in…
Oligodendrocytes in multiple sclerosis lesions exhibit epigenetic silencing that precludes myelin restoration. This study identifies a small-molecule inhibitor that counteracts epigenetic silencing, effectively enhancing myelin…
As immunotherapy makes its way into the perioperative setting, a growing number of clinical trials are expanding the evidence base for resectable non-small cell lung…
Martinez-Sarmiento et al. demonstrate that, during heterokaryon reprogramming, global chromatin decondensation and loss of repressive histone modifications occur at late stages after cell fusion. Activation of…