Vasculitis
Substantial advancements in the diagnosis and treatment of the three major forms of vasculitis—antineutrophil cytoplasmic antibody-associated vasculitis, giant cell arteritis, and IgG4-related disease—have occurred over the past two decades. However, clinical management of patients with vasculitis remains challenging, and treatment options are limited. Glucocorticoids remain the mainstay of therapy, with two targeted therapies (tocilizumab and avacopan) now approved for specific types of vasculitis.