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Mashup Score: 2Peter van Galen (@vangalenlab.bsky.social) - 3 month(s) ago
We integrate cell biology and bioinformatics to study the blood system and identify new strategies to improve human health. Brigham and Women’s Hospital, Harvard Medical School, Broad Institute. https://vangalenlab.bwh.harvard.edu
Source: bsky.appCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 1Please wait whilst we redirect you - 12 month(s) ago
About ScienceDirectRemote accessShopping cartAdvertiseContact and supportTerms and conditionsPrivacy policyWe use cookies to help provide and enhance our service and tailor content and ads. By continuing you agree to the use of cookies.Copyright © 2023 Elsevier B.V. or its licensors or contributors. ScienceDirect® is a registered trademark of Elsevier B.V.ScienceDirect® is a registered trademark…
Source: www.sciencedirect.comCategories: Hem/Oncs, Latest HeadlinesTweet-
Very happy with this commentary on a great paper where @YokeSengLee and I distilled down the key messages. Enjoy reading! https://t.co/dq1eZPjWTl
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Mashup Score: 0Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia - Leukemia - 1 year(s) ago
Mitochondrial metabolism recently emerged as a critical dependency in acute myeloid leukemia (AML). The shape of mitochondria is tightly regulated by dynamin GTPase proteins, which drive opposing fusion and fission forces to consistently adapt bioenergetics to the cellular context. Here, we showed that targeting mitochondrial fusion was a new vulnerability of AML cells, when assayed in…
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet-
Targeting mitochondrial dysfunction in acute myeloid leukemia @LeukemiaJnl https://t.co/rIwBrTWWtC
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Mashup Score: 37From cell line to command line - 1 year(s) ago
$39.99 How you can transform from a wet biologist to a computational biologist like I did.“The best time to start learning is ten years ago; the second best time to start learning is right now.”What you will learn:Essential skills you need for biological or any data analysisTips and mistakes that I have learned from my ten years of computational experienceResource for further reading and…
Categories: Hem/Oncs, Latest HeadlinesTweet-
RT @tangming2005: 1/ My new book 'From Cell line to Command line' is finally here https://t.co/R4bsCE6Io8 Grab it to start transforming yo…
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Mashup Score: 1
A meta-analysis database for single cell RNA sequencing data. Search across datasets, studies, download data, and perform advanced visualization.
Source: panglaodb.seCategories: Hem/Oncs, Latest HeadlinesTweet-
The ability to score cells for good marker genes is most helpful for scRNA-seq cell type annotation. Here are three resources. Further development is warranted 🟣 PanglaoDB https://t.co/JhIXYi66gp 🟡 CellMarker https://t.co/CAqR4pU4k9 🟢 ABC portal https://t.co/hL6KB01pDe
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Mashup Score: 2ASH Foundation 5K run - Peter V.'s 3.3 mi run - 1 year(s) ago
Strava Free app for Android and iPhone
Source: StravaCategories: Hem/Oncs, Latest HeadlinesTweet-
#ASH22 Foundation 5K thanks for keeping me on pace @challenlab https://t.co/c8R2BjTd5y https://t.co/QphB9CK0oF
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Mashup Score: 0CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response - 1 year(s) ago
Cancer is driven by somatic mutations that provide a fitness advantage. While targeted therapies often focus on the mutated gene or its direct downstream effectors, imbalances brought on by cell-state alterations may also confer unique vulnerabilities. In myeloproliferative neoplasms (MPN), somatic mutations in the calreticulin (CALR) gene are disease-initiating through aberrant binding of mutant…
Source: www.nature.comCategories: Hem/Oncs, Latest HeadlinesTweet-
Deepening our understanding of ER stress in myeloid malignancies - it has been such a pleasure working with @jonas_jutzi @AnnaMarneth @MullallyLab 😁 https://t.co/naET3TolIM https://t.co/PPlPfanCGF
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Mashup Score: 0Full-length cDNA amplification · Benchling - 1 year(s) ago
Use Benchling’s DNA editor to create your sequences.
Source: benchling.comCategories: Hem/Oncs, Latest HeadlinesTweet-
Want to amplify your 10x 3' scRNA-seq full-length cDNA to enrich additional modalities*? Here's how we do it: https://t.co/fLe3ew9aZh *e.g. mtDNA variants (MAESTER), somatic nuclear mutations (GoT), T cell receptor transcripts (TREK-seq) 🧬→🧬🧬🧬 @nursariipek @danielssozi_
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Mashup Score: 17
Multi-modality single-cell sequencing determines genotype, transcriptome and methylome information in cells from individuals with DNMT3A R882 mutated clonal hematopoiesis, allowing for the comparison of mutant and wild-type cells from the same individuals.
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet-
I will admit this is something I've been wanting to do for a long time. Congrats @AnnaEnim, @nevnevv, @FrancoIzzo85, @RobertMMyers, Rekha Murali, @IreneGhobrial, and @landau_lab! Really nice work 😀🍾 https://t.co/GLfnqNeJcv
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Mashup Score: 02022 BRIght Futures Prize – Discover Brigham - 2 year(s) ago
Since 2012, we have awarded ten research projects with $100,000 BRIght Futures Prizes, supported by the philanthropic contributions to the BRIght Futures Fund. These are just some of the exciting ideas and projects that have been transformed in large part due to donor support.As part of the 2022 Cambridge Science Festival, Brigham & Women’s Hospital (BWH) will showcase interactions between local…
Source: www.discoverbrigham.orgCategories: Hem/Oncs, Latest HeadlinesTweet-
An interesting strategy - public voting on the finalists of a science award. Support @SandraMcAllist4 and @EMittendorfMD so they can help Black breast cancer patients @BrighamWomens https://t.co/gUExBpE4Ea https://t.co/JErt9yS32o
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Come join a more sympathetic alternative to 𝕏 → https://t.co/denSiIowAj I'm hoping to see more members of our scientific community soon ❤️ Read more: https://t.co/XJ16AXKeSf