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Mashup Score: 46Nextstrain / monkeypox - 2 year(s) ago
Genomic epidemiology of monkeypox virus
Source: nextstrain.orgCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 7monkeypox/latest.csv at main · globaldothealth/monkeypox - 2 year(s) ago
Monkeypox 2022 repository. Contribute to globaldothealth/monkeypox development by creating an account on GitHub.
Source: GitHubCategories: Healthcare Professionals, Latest HeadlinesTweet-
This is data from https://t.co/NDRnnG1ZCl and has had a 7-day smoothing applied and all y-axes are shown on a log scale. 2/10
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Mashup Score: 23SARS-CoV-2 variant dynamics across US states show consistent differences in effective reproduction numbers - 2 year(s) ago
Accurately estimating relative transmission rates of SARS-CoV-2 Variant of Concern and Variant of Interest viruses remains a scientific and public health priority. Recent studies have used the sample proportions of different variants from sequence data to describe variant frequency dynamics and relative transmission rates, but frequencies alone cannot capture the rich epidemiological…
Source: bedford.ioCategories: Healthcare Professionals, Latest HeadlinesTweet-
We can assess variant-specific Rt using method developed by @marlinfiggins (https://t.co/Uq7Nl2mI2R), where we observe current Rt for BA.2.12.1 of ~1.0, compared to Rt of BA.4 of ~1.2 and BA.5 of ~1.5. 7/12 https://t.co/e91i6r8uNA
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Mashup Score: 12rt-from-frequency-dynamics/results/omicron-countries-split at master · blab/rt-from-frequency-dynamics - 2 year(s) ago
Contribute to blab/rt-from-frequency-dynamics development by creating an account on GitHub.
Source: GitHubCategories: Healthcare Professionals, Latest HeadlinesTweet-
More detailed plotting of variant circulation across countries is viewable at https://t.co/msfICPDm63 and across states is viewable at https://t.co/DOQ3doVqUD. 10/12
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Mashup Score: 50SARS-CoV-2 Omicron BA.2.12.1, BA.4, and BA.5 subvariants evolved to extend antibody evasion - 2 year(s) ago
The Omicron subvariant BA.2 accounts for a large majority of the SARS-CoV-2 infection worldwide today. However, its recent descendants BA.2.12.1 and BA.4/5 have surged dramatically to become dominant in the United States and South Africa, respectively. That these novel Omicron subvariants carry additional mutations in their spike proteins raises concerns that they may further evade neutralizing…
Source: bioRxivCategories: Healthcare Professionals, Latest HeadlinesTweet-
There is a notable drop in neutralization titer against BA.4 and BA.5 viruses in boosted individuals and individuals with BA.1 breakthrough infections (figure from Qian Wang, David Ho and colleagues https://t.co/7rI08qMVPC). 11/12 https://t.co/CDhudKrDxo
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Mashup Score: 18Nextstrain / monkeypox - 2 year(s) ago
Genomic epidemiology of monkeypox virus
Source: nextstrain.orgCategories: Healthcare Professionals, Latest HeadlinesTweet-
Thanks to data sharing by @irj_pt, @unibw_m, @CDCgov, @KU_Leuven, we can see relationships among sequenced viruses at https://t.co/EgWDVnoSrh, where viruses from the current outbreak (in yellow) are nearly identical to one another suggesting a single introduction event. 3/9 https://t.co/5YucFQManT
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Mashup Score: 11Multi-country outbreak of Monkeypox virus: genetic divergence and first signs of microevolution - 2 year(s) ago
Joana Isidro1, Vítor Borges1, Miguel Pinto1, Rita Ferreira1, Daniel Sobral1, Alexandra Nunes1, João Dourado Santos1, Verónica Mixão1, Daniela Santos2, Silvia Duarte2, Luís Vieira2, Maria José Borrego3, Sofia Núncio4, Ana Pelerito4, Rita Cordeiro4, João Paulo Gomes1,*. 1 Genomics and Bioinformatics Unit, Department of Infectious Diseases, National Institute of Health Doutor Ricardo Jorge (INSA),…
Source: VirologicalCategories: Healthcare Professionals, Latest HeadlinesTweet-
That said, there appear to be two shared mutations in two of the genomes from Portugal that suggest the potential for some degree of resolution of transmission linkages by genomic sequencing. For more details see @isidro_joana et al https://t.co/rZTGL0POBv. 7/9 https://t.co/wQel07eGnM
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Mashup Score: 24Discussion of on-going MPXV genome sequencing - 2 year(s) ago
This topic is for discussion of the 2022 monkeypox outbreak genomes and phylogenies
Source: VirologicalCategories: Healthcare Professionals, Latest HeadlinesTweet-
Additionally, genomic data may help resolve origins of the monkeypox outbreak. Of interest are the ~47 mutations on the branch connecting previously observed viruses from 2018 to viruses observed in 2022, but there are still many questions here. 8/9 https://t.co/dQKiBu3Vuu
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Mashup Score: 222
Data on the real-world effectiveness and impact of the COVID-19 vaccines.
Source: GOV.UKCategories: Infectious Disease, Latest HeadlinesTweet-
BA.2's advantage over BA.1 appears to be due to intrinsic transmissibility. The antigenically important S1 region of spike is highly similar between BA.1 and BA.2 and we observe similar vaccine effectiveness between BA.1 and BA.2 (figure from @UKHSA https://t.co/yE8DaWr7pc). 4/17 https://t.co/vnOrx0nMts
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Mashup Score: 206Nextstrain / nextclade / sars-cov-2 - 2 year(s) ago
SARS-CoV-2 phylogeny
Source: nextstrain.orgCategories: Infectious Disease, Latest HeadlinesTweet-
With BA.2's global dominance we expect further evolution to occur on top of BA.2. @PangoNetwork now classifies 21 sublineages of BA.2. However, most of these sublineages are characterized by mutations thought to have little impact (figure from https://t.co/2mHlFTQqSy). 5/17 https://t.co/U17s1pciR4
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@HelenBranswell @CDCgov @firefoxx66 You can see sequences from Florida (MPXV_USA_2022_FL001) and Virginia (MPXV_USA_2022_VA001) up at https://t.co/EgWDVnoSrh now. Both genomes and their connecting branch show patterns of mutation suggestive of continued faster evolution via APOBEC editing.