-
Mashup Score: 16
Percentage of people testing positive for coronavirus (COVID-19) in private residential households in England, Wales, Northern Ireland and Scotland.
Source: www.ons.gov.ukCategories: Healthcare Professionals, Latest HeadlinesTweet
-
Mashup Score: 9
Findings from the Coronavirus (COVID-19) Infection Survey for England.
Source: www.ons.gov.ukCategories: Healthcare Professionals, Latest HeadlinesTweet-
While here I'm showing estimated prevalence (proportion of individuals testing positive) from the @ONS infection survey (https://t.co/pjCJZ64N2E). The initial Omicron surge results in the most concurrent infections, but later waves in 2022 result in comparable prevalence. 6/16 https://t.co/sukR39E0Ph
-
-
Mashup Score: 4
Correspondence from The New England Journal of Medicine — Viral Dynamics of SARS-CoV-2 Variants in Vaccinated and Unvaccinated Persons
Source: New England Journal of MedicineCategories: Healthcare Professionals, Latest HeadlinesTweet-
The 30-fold ratio can be converted into case detection rate by dividing by the span of time during which the average infection tests positive. I'll use 10-days for the pre-Omicron period (https://t.co/aB6XryK1De). This gives a detection rate of 1 case per ~3 infections. 9/16
-
-
Mashup Score: 5Quantifying the impact of immune history and variant on SARS-CoV-2 viral kinetics and infection rebound: a retrospective cohort study - 1 year(s) ago
Background The combined impact of immunity and SARS-CoV-2 variants on viral kinetics during infections has been unclear. Methods We characterized 2,875 infections from the National Basketball Association occupational health cohort identified between June 2020 and January 2022 using serial RT-qPCR testing. Logistic regression and semi-mechanistic viral RNA kinetics models were used to quantify…
Source: medRxivCategories: Healthcare Professionals, Latest HeadlinesTweet-
Likewise, the current 300-fold ratio can be converted assuming the average infection tests positive for 8-days in 2022 (https://t.co/jUO7K3rBJf). This would imply a current case detection rate of 1 case per ~38 infections. 10/16
-
-
Mashup Score: 31Pathogen phylogenetics for decision making - 2 year(s) ago
Trevor Bedford (@trvrb) Fred Hutchinson Cancer Center / Howard Hughes Medical Institute 23 Aug 2022 From Trees to Public Health Policy Module International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology Slides at:…
Source: bedford.ioCategories: Healthcare Professionals, Latest HeadlinesTweet-
I was invited by @VandammeAm and other organizers of the #VEME2022 Virus Evolution and Molecular Epidemiology Workshop to present my perspective on applying pathogen phylogenetics for decision making. Slides from my talk are available here: https://t.co/dcRz1LSpbP.
-
-
Mashup Score: 84Protection of SARS-CoV-2 natural infection against reinfection with the Omicron BA.4 or BA.5 subvariants - 2 year(s) ago
This study estimates the effectiveness of previous infection with SARS-CoV-2 in preventing reinfection with Omicron BA.4/BA.5 subvariants using a test-negative, case–control study design. Cases (SARS-CoV-2-positive test results) and controls (SARS-CoV-2-negative test results) were matched according to sex, 10-year age group, nationality, comorbid condition count, calendar week of testing, method…
Source: medRxivCategories: Infectious Disease, Latest HeadlinesTweet-
Although it's difficult to estimate long-term rate of R→S for SARS-CoV-2, we can extrapolate from @HebAltarawneh et al's finding of 76% effectiveness of BA.1 infection to prevent BA.4/BA.5 reinfection (https://t.co/tPcceilmmk). 9/11
-
-
Mashup Score: 747Opinion | Endemic Covid-19 Looks Pretty Brutal - 2 year(s) ago
100,000 annual deaths may be as good as it gets.
Source: www.nytimes.comCategories: Infectious Disease, Latest HeadlinesTweet-
1/ Endemic Covid-19 Looks Pretty Brutal by @dwallacewells for @nytimes https://t.co/BBHULZIxl3 We haven't had an explicit conversation about this👇🏽 Why not? https://t.co/YP8lqVRzvC
-
This level of circulation and severe outcomes (including long COVID in addition to death) combine to make "endemic" COVID-19 a serious ongoing health burden. Here, @dwallacewells describes this viscerally as "looking pretty brutal". 5/5 https://t.co/kmiWWJnH5I
-
-
Mashup Score: 96VRBPAC June 28, 2022 Meeting Announcement - 2 year(s) ago
This is the main page for the CBER Vaccines and Related Biological Products Advisory Committee June 28, 2022 Meeting Announcement.
Categories: Healthcare Professionals, Latest HeadlinesTweet-
The @US_FDA VRBPAC committee will be meeting tomorrow to discuss variant-specific COVID-19 vaccines (https://t.co/Dm62X28f2K). Based on present observations, I would argue that the most important metric to optimize are titers against BA.4/BA.5 viruses. 1/10
-
-
Mashup Score: 12A Bivalent Omicron-containing Booster Vaccine Against Covid-19 - 2 year(s) ago
Background Updated vaccination strategies against acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern are needed. Interim results of the safety and immunogenicity of the bivalent omicron-containing mRNA-1273.214 booster candidate are presented. Methods In this ongoing, phase 2/3 trial, the 50-μg bivalent vaccine mRNA-1273.214 (25-μg each ancestral Wuhan-Hu-1 and omicron…
Source: medRxivCategories: Healthcare Professionals, Latest HeadlinesTweet-
The recent @moderna_tx trial results of a bivalent wildtype + BA.1 vaccine (https://t.co/D40XYenwps) are interesting in this regard. This shows geometric mean titer (GMT) against Omicron BA.1 of 1474 with monovalent wildtype booster and 2372 with bivalent BA.1 booster. 6/10 https://t.co/p8QKHwqJHJ
-
-
Mashup Score: 33F.D.A. May Move Toward Updating Vaccines - 2 year(s) ago
Scientists had high hopes for a new coronavirus vaccine that combines the existing formulation with one targeting Omicron, but many are not impressed by the results.
Source: www.nytimes.comCategories: Healthcare Professionals, Latest HeadlinesTweet-
Note here that I fully expect further evolution to occur in the coming months, but that this evolution will most likely be on top of BA.4/BA.5 and so this continued evolution shouldn't dissuade vaccine updates (https://t.co/GmBVg88ZHf). 9/10 https://t.co/XpgzSTnmNJ
-
Although there are things like wastewater surveillance in the US, I believe the gold standard to assess case detection rate is the @ONS infection survey (https://t.co/Wo9jctWBvi) that has continued to test swabs every week in the UK regardless of individual's symptom status. 4/16