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Mashup Score: 44Paraneoplastic Calmodulin Kinase‐Like Vesicle‐Associated Protein (CAMKV) Autoimmune Encephalitis - 17 day(s) ago
Annals of Neurology is a leading neurology journal from the American Neurological Association focusing on diseases of the human nervous system.
Source: onlinelibrary.wiley.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 125Cognitively healthy centenarians are genetically protected against Alzheimer's disease - 20 day(s) ago
BACKGROUND Alzheimer’s disease (AD) prevalence increases with age, yet a small fraction of the population reaches ages > 100 years without cognitive decline. We studied the genetic factors associate…
Categories: General Medicine News, NeurologyTweet
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Mashup Score: 10Racial and ethnic differences in plasma biomarker eligibility for a preclinical Alzheimer's disease trial - 21 day(s) ago
INTRODUCTION In trials of amyloid-lowering drugs for Alzheimer’s disease (AD), differential eligibility may contribute to under-inclusion of racial and ethnic underrepresented groups. We examined pl…
Categories: General Medicine News, NeurologyTweet
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Mashup Score: 2Diversity, equity and inclusion in neurology - 22 day(s) ago
This Series highlights the importance of efforts to improve diversity, equity and inclusion (DEI) in the neurology community and in neurological care to …
Source: www.nature.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 52Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson’s disease - 23 day(s) ago
Nature Medicine – An exploratory analysis of the 1-year clinical trial PASADENA in individuals with early-stage Parkinson’s disease suggests that prasinezumab might reduce motor signs…
Source: www.nature.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 52Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson’s disease - 23 day(s) ago
Nature Medicine – An exploratory analysis of the 1-year clinical trial PASADENA in individuals with early-stage Parkinson’s disease suggests that prasinezumab might reduce motor signs…
Source: www.nature.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 24Neuronal activity drives glymphatic waste clearance - 24 day(s) ago
Nature Reviews Neurology – Two new studies show that clearance of waste, including pathogenic amyloid, through the glymphatic system is driven by synchronized neuronal activity.
Source: www.nature.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 6
Nature Reviews Neurology – Nature Reviews Neurology is interviewing individuals who are driving efforts to address disparities in neurology through a broad spectrum of diversity, equity and…
Source: www.nature.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 238Neurofilaments as biomarkers in neurological disorders — towards clinical application - 27 day(s) ago
Nature Reviews Neurology – Neurofilaments have been validated as specific body fluid biomarkers of neuro-axonal injury. In this Review, Khalil and colleagues provide an update on the structure and…
Source: www.nature.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 3Specific nanoprobe design for MRI: Targeting laminin in the blood-brain barrier to follow alteration due to neuroinflammation - 27 day(s) ago
Chronic neuroinflammation is characterized by increased blood-brain barrier (BBB) permeability, leading to molecular changes in the central nervous system that can be explored with biomarkers of active neuroinflammatory processes. Magnetic resonance imaging (MRI) has contributed to detecting lesions and permeability of the BBB. Ultra-small superparamagnetic particles of iron oxide (USPIO) are used as contrast agents to improve MRI observations. Therefore, we validate the interaction of peptide-88 with laminin, vectorized on USPIO, to explore BBB molecular alterations occurring during neuroinflammation as a potential tool for use in MRI. The specific labeling of NPS-P88 was verified in endothelial cells (hCMEC/D3) and astrocytes (T98G) under inflammation induced by interleukin 1β (IL-1β) for 3 and 24 hours. IL-1β for 3 hours in hCMEC/D3 cells increased their co-localization with NPS-P88, compared with controls. At 24 hours, no significant differences were observed between groups. In T98
Source: journals.plos.orgCategories: General Medicine News, NeurologyTweet
Paraneoplastic Calmodulin Kinase‐Like Vesicle‐Associated Protein (CAMKV) Autoimmune Encephalitis https://t.co/bSoRXGxEa5