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Mashup Score: 28C21ORF2 mutations point towards primary cilia dysfunction in amyotrophic lateral sclerosis - 4 day(s) ago
De Decker et al. show that ALS-associated mutations in C21ORF2 disrupt primary cilia on motor neurons, leading to defective downstream sonic hedgehog signa
Source: academic.oup.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 66Identifying Individuals in the Prodromal Phase of Parkinson's Disease: A Prospective Cohort Study - 4 day(s) ago
Objective We prospectively evaluated how well combinations of signs and symptoms can identify individuals in the prodromal phase of Parkinson’s disease (PD). Methods The study comprised 6,108 men …
Source: onlinelibrary.wiley.comCategories: General Medicine News, NeurologyTweet-
"Combinations of key signs and symptoms strongly predict future clinically manifest Parkinson disease" https://t.co/hfFgmObXhQ
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Mashup Score: 4A prospective study of associations between accelerated biological aging and twenty musculoskeletal disorders - 5 day(s) ago
Communications Medicine – Wei et al. investigate the link between accelerated biological aging and the risk of musculoskeletal disorders, highlighting sex-related disparities. Age acceleration…
Source: www.nature.comCategories: General Medicine News, NeurologyTweet-
"Accelerated biological aging is significantly associated with the incidence of several musculoskeletal disorders" https://t.co/PGMAzFDBj0
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Mashup Score: 15Alzheimer's Disease Risk Gene SORL1 Promotes Receptiveness of Human Microglia to Pro‐Inflammatory Stimuli - 6 day(s) ago
Sorting protein-related receptor containing class A repeats (SORLA) is an intracellular trafficking receptor encoded by the Alzheimer’s disease (AD) gene SORL1 (sortilin-related receptor 1). Recent f…
Source: onlinelibrary.wiley.comCategories: General Medicine News, NeurologyTweet-
Alzheimer's Disease Risk Gene SORL1 Promotes Receptiveness of Human Microglia to Pro‐Inflammatory Stimuli https://t.co/6CxxxEj8Xu
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Mashup Score: 109Brain change trajectories in healthy adults correlate with Alzheimer’s related genetic variation and memory decline across life - 6 day(s) ago
Nature Communications – This study shows that among healthy adults tracked across their lives, brain atrophy rates correlate with genetic risk for Alzheimer’s and memory decline, and that…
Source: www.nature.comCategories: General Medicine News, NeurologyTweet-
Brain change trajectories in healthy adults correlate with Alzheimer’s related genetic variation and memory decline across life https://t.co/97hqSSmsls
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Mashup Score: 17Alpha-synuclein seed amplification assay longitudinal outcomes in Lewy body disease spectrum - 6 day(s) ago
Mastrangelo et al. assessed the longitudinal performance of a seed amplification assay measuring misfolded alpha-synuclein in patients with Lewy body disea
Source: academic.oup.comCategories: General Medicine News, NeurologyTweet-
Alpha-synuclein seed amplification assay longitudinal outcomes in Lewy body disease spectrum https://t.co/avEIHdyC1L
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Mashup Score: 155
Nature Reviews Neurology – The immune system plays a major part in neurodegenerative diseases. In this Review, Weiner considers the contributions of several components of the immune system in…
Source: www.nature.comCategories: General Medicine News, NeurologyTweet-
New online! Immune mechanisms and shared immune targets in neurodegenerative diseases https://t.co/fAnATMrviZ https://t.co/kItGpziQlm
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Mashup Score: 155
Nature Reviews Neurology – The immune system plays a major part in neurodegenerative diseases. In this Review, Weiner considers the contributions of several components of the immune system in…
Source: www.nature.comCategories: General Medicine News, NeurologyTweet-
New online! Immune mechanisms and shared immune targets in neurodegenerative diseases https://t.co/fAnATMrviZ https://t.co/kItGpziQlm
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Mashup Score: 38A critical role of action-related functional networks in Gilles de la Tourette syndrome - 7 day(s) ago
Nature Communications – By leveraging diverse datasets from brain stimulation therapy for Tourette Syndrome and tic-inducing brain lesions, Baldermann et al. reveal a critical role of…
Source: www.nature.comCategories: General Medicine News, NeurologyTweet-
A critical role of action-related functional networks in Gilles de la Tourette syndrome https://t.co/KWcjDJDJ9L
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Mashup Score: 7
AbstractBackground. Glioblastoma is the most aggressive adult primary brain cancer, characterized by significant heterogeneity, posing challenges for patie
Source: academic.oup.comCategories: General Medicine News, NeurologyTweet-
Machine learning-based prognostic subgrouping of glioblastoma https://t.co/1tYYtM6FhJ
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C21ORF2 mutations point towards primary cilia dysfunction in amyotrophic lateral sclerosis https://t.co/XSjqzvBFCt