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Mashup Score: 7Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics - 7 month(s) ago
Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies.
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 3Annual Meeting - Society for Basic Urologic Research - 7 month(s) ago
Join us for the 30th Annual Meeting of the Society for Basic Urologic Research. This milestone event will offers an outstanding program featuring a world-class faculty.
Source: sbur.orgCategories: General Medicine News, Hem/OncsTweet-
RT @jklee_lab: Trainees in urological research--register for #SBUR2023 in San Antonio, TX on November 9-12 https://t.co/M1Q8JuEKuo and att…
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Mashup Score: 1Annual Meeting - Society for Basic Urologic Research - 7 month(s) ago
Join us for the 30th Annual Meeting of the Society for Basic Urologic Research. This milestone event will offers an outstanding program featuring a world-class faculty.
Source: sbur.orgCategories: General Medicine News, Hem/OncsTweet-
RT @jklee_lab: Trainees in urological research--register for #SBUR2023 in San Antonio, TX on November 9-12 https://t.co/M1Q8JuEKuo and att…
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Mashup Score: 78Harald zur Hausen, virologist who linked viruses to cancer (1936–2023) - 10 month(s) ago
Nature – Nobel laureate who laid the foundations for vaccines to prevent cervical cancer.
Source: www.nature.comCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @Nature: Obituary: Harald zur Hausen, virologist who linked viruses to cancer (1936–2023) https://t.co/npGw6S7H4h
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Mashup Score: 2Histone Demethylase LSD1 Regulates Kidney Cancer Progression by Modulating Androgen Receptor Activity - 4 year(s) ago
Kidney cancer is one of the most difficult cancers to treat by targeted and radiation therapy. Therefore, identifying key regulators in this cancer is especially important for finding new drugs. We focused on androgen receptor (AR) regulation by its epigenetic co-regulator lysine-specific histone demethylase 1 (LSD1) in kidney cancer development. LSD1 knock-down in kidney cancer cells decreased…
Source: MDPICategories: Hem/Oncs, Latest HeadlinesTweet-
IJMS | Free Full-Text | Histone Demethylase LSD1 Regulates Kidney Cancer Progression by Modulating Androgen Receptor Activity @AlumkalJoshi https://t.co/eGeNBxJfHp
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Mashup Score: 0Germline sequencing DNA repair genes in 5,545 men with aggressive and non-aggressive prostate cancer - 4 year(s) ago
AbstractBACKGROUND. There is an urgent need to identify factors specifically associated with aggressive prostate cancer (PCa) risk. We investigated whether rar
Source: OUP AcademicCategories: Hem/Oncs, Latest HeadlinesTweet-
Germline sequencing DNA repair genes in 5,545 men with aggressive and non-aggressive prostate cancer | JNCI: Journal of the National Cancer Institute | Oxford Academic https://t.co/b6DviCc5Ni
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Mashup Score: 1Antihistamine Drug Ebastine inhibits cancer growth by targeting Polycomb Group Protein EZH2 - 4 year(s) ago
Enhancer of Zester Homolog 2 (EZH2), a histone lysine methyltransferase and the catalytic component of Polycomb Repressive Complex 2, has been extensively investigated as a chromatin regulator and a transcriptional suppressor by methylating H3 at lysine 27 (H3K27). EZH2 is upregulated or mutated in most cancers, and its expression levels are negatively associated with clinical outcomes. However,…
Source: Molecular Cancer TherapeuticsCategories: Hem/Oncs, Latest HeadlinesTweet-
Antihistamine Drug Ebastine inhibits cancer growth by targeting Polycomb Group Protein EZH2 | Molecular Cancer Therapeutics https://t.co/2IaGbggzvn
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Mashup Score: 2Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases - 4 year(s) ago
Metastatic melanoma is associated with a poor prognosis and understanding the genetic features of metastases may enable better treatment strategies. Here, the authors analyse multiple metastases from individual patients finding high levels of heterogeneity in metastases from different organs.
Source: Nature CommunicationsCategories: Hem/Oncs, Latest HeadlinesTweet-
Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases | Nature Communications https://t.co/neU0MoQK4T
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Mashup Score: 4Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action - 4 year(s) ago
Large-scale screens of chemical and genetic vulnerabilities in cancer are typically limited to simple readouts of cell viability. Here, the authors develop a method for profiling post-perturbation transcriptional responses across large pools of cancer cell lines, enabling deep characterization of shared and context-specific responses.
Source: Nature CommunicationsCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @CancerDepMap: We’re excited to share our new paper in Nature Communications (https://t.co/aDwftUF2SN), describing our platform that ena…
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Mashup Score: 2Cofactor Genomics - 4 year(s) ago
SAN FRANCISCO, Calif. – August 20, 2020 – Cofactor Genomics, the company bridging the precision medicine gap, announced today that the United States Patent and Trademark Office (USPTO) has granted Patent No. 10636512 protecting the Company’s predictive immune modeling technology. The patent covers translation of RNA present in tumors into immune composition and its use in predicting response to…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Great advancement of bench science making clinical impact | Cofactor Genomics - Cofactor Genomics Announces New U.S. Patent Granted for Predictive Immune Modeling Technology https://t.co/8zQi6HX4KP
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RT @dechen_lin: Delighted to share my latest editorial on spatial transcriptomics in cancer research: 👇https://t.co/IuxLMetUqe https://t.co…