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Mashup Score: 3
and functional effects of RF RDN in a preclinical model. Methods: Bilateral RF RDN was performed in 20 normotensive swine. Renal tissue samples were obtained in the RDN-treated groups at 7 (n = 6), 28 (n = 6), and 180 days (n = 8) postprocedure for quantification of cortical norepinephrine (NE) levels and renal cortical axon density. Tissue fibrosis, necrosis and downstream nerve fiber atrophy (axonal loss) were also scored for each sample. Three additional untreated groups (n = 6, n = 6 and n = 8, respectively) served as control. Results: Pathologic nerve changes were characterized by necrosis in the ablated region at 7 days that partially resolved by 28 days and fully resolved at 180 days. Axonal loss was apparent within and downstream to the ablation regions and was evident at 7, 28 and 180 days in the main vessel and branch vessels. Consequently, renal cortical axon density and corresponding cortical NE levels were significantly reduced at 7 days in the RDN vs. control group and re
Source: journals.lww.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 1Catheter-Based Renal Denervation: 9-Year Follow-Up Data on Safety and Blood Pressure Reduction in Patients With Resistant Hypertension - 12 day(s) ago
Background: Recent sham-controlled randomized clinical trials have confirmed the safety and efficacy of catheter-based renal denervation (RDN). Long-term safety and efficacy data beyond 3 years are s
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 79Emergency Management of Anaphylaxis - 2 month(s) ago
emergency management of anaphylaxis (pdf) emergency management of anaphylaxis (png)
Source: emupdates.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 8
Background: In some randomized clinical trials, transradial access (TRA) compared with transfemoral access (TFA) was associated with lower mortality in patients with coronary artery disease undergoin
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 24Cost-effectiveness of intravascular ultrasound-guided percutaneous intervention in patients with acute coronary syndromes: A UK perspective - PubMed - 2 month(s) ago
From a UK healthcare perspective, an IVUS-guided PCI strategy was highly cost-effective over angiography alone amongst ACS patients undergoing DES implantation due to the medium- and long-term reduction in repeat PCI, death, and MI.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 2
BackgroundExperimental studies suggest that low wall shear stress (WSS) promotes plaque development and high WSS is associated with plaque destabilization. We hypothesized that low-WSS segments in pa
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet-
@djc795 @DocSavageTJU @mmamas1973 @SandeepNathanMD @GreggWStone @SVRaoMD @mirvatalasnag @BinitaShahMD @azeemlatib @SripalBangalore @SuzanneJBaron @aayshacader @mandeep_mayo @Hragy @fischman_david @SCAI @cardiojaydoc02 @CardioNerds @Coronary4front @angioplastyorg @jedicath @timir_paul @Pooh_Velagapudi @lamelaspablo @vass_vassiliou You should live in Wales 😂 Low shear stress accelerates plaque - maybe LIMA and major septal patency relates partly to high shear effects along their paths? https://t.co/fqClDVXKes https://t.co/Gwx01bwuTw
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Mashup Score: 2
Intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) has been shown in clinical trials, registries, and meta-analyses to reduce recurrent major adverse cardiovascular events after PCI. However, IVUS utilization remains low. An increasing number of high-risk or complex coro …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet-
@EricSecemskyMD @SCAI @VIVAPhysicians @VMJ_SVM @ACCinTouch Absence of routine IVI in coro PCI is not systemic failure. Best RCT in Western population failed to show benefit & not impossible that lessons of routine IVI been partially learned. Have been advocating ICI for 15 yrs, but until https://t.co/gGKpCDvqfK completes, IVI is Class 2A
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Mashup Score: 6Modern Treatment of Pulmonary Embolism (USCDT vs MT): Results From a Real-World, Big Data Analysis (REAL-PE) - 3 month(s) ago
Advanced therapies are increasingly utilized to treat pulmonary embolism (PE). A unique data platform allows access to electronic health record data for comparison of the safety of PE therapies.
Source: www.jscai.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 4
Due to the bleeding risk of full-dose systemic thrombolysis and the lack of major trials focusing on the clinical benefits of catheter-directed treatm…
Source: www.sciencedirect.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 4A Randomized Trial of the Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Intermediate-Risk Pulmonary Embolism: The OPTALYSE PE Trial - 3 month(s) ago
The aim of this study was to determine the lowest optimal tissue plasminogen activator (tPA) dose and delivery duration using ultrasound-facilitated c…
Source: www.sciencedirect.comCategories: General Medicine News, CardiologistsTweet
Pre-clinical model suggests that once we have got the nerves, we have likely got them. https://t.co/XFzUWsQkZO