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Mashup Score: 19UK Cancer and Transition Service - Transplus - 23 day(s) ago
Review of available evidence related to treatment decisions. Signposting to other important services such as therapy, psychosexual counselling, and fertility preservation. You will also have the option to participate in research to help improve cancer care for the trans and non-binary community. UCATS is a new service for the trans and non-binary community. 1 in 2 of us will get cancer at some point in our lifetime. For trans and non-binary people a cancer diagnosis may be made more difficult because of:
Source: www.wearetransplus.co.ukCategories: General Medicine News, Oncologists2Tweet
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Mashup Score: 29Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer - 1 month(s) ago
Aneuploidy, defined as the loss and gain of whole and part chromosomes, is a near-ubiquitous feature of cancer genomes, is prognostic, and likely an important determinant of cancer cell biology. In colorectal cancer (CRC), aneuploidy is found in virtually all tumours, including precursor adenomas. However, the temporal evolutionary dynamics that select for aneuploidy remain broadly uncharacterised. Here we perform genomic analysis of 755 samples from a total of 167 patients with colorectal-derived neoplastic lesions that cross-sectionally represent the distinct stages of tumour evolution, and longitudinally track individual tumours through metastasis and treatment. Precancer lesions (adenomas) exhibited low levels of aneuploidy but high intra-tumour heterogeneity, whereas cancers had high aneuploidy but low heterogeneity, indicating that progression is through a genetic bottleneck that suppresses diversity. Individual CRC glands from the same tumour have similar karyotypes, despite pri
Source: www.biorxiv.orgCategories: General Medicine News, Oncologists2Tweet
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Mashup Score: 51Equitable cancer care for the LGBTQIA+ community - 2 month(s) ago
Read the second blog from our International Women’s Day series exploring the barriers to equitable cancer care for the LGBTQIA+ community.
Source: www.macmillan.org.ukCategories: General Medicine News, Oncologists2Tweet-
Pleased to work with @macmillancancer on this blog on equitable #cancercare for #LGBTQ populations & feature work of some great individuals & organisations @OUTpatientsUK @DrEstherMoss1 @GIRESUK @DrJenOG @56TSoho @ssjac79 @hospiceuk #selftistudy ๐ณ๏ธโ๐ ๐ณ๏ธโโง๏ธ https://t.co/81Lmamzcit
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Mashup Score: 4Fox Fisher (@thefoxfisher) โข Instagram reel - 2 month(s) ago
thefoxfisher on February 27, 2024: “Are you trans and living in the UK? ๐ณ๏ธโโง๏ธโจA better way to test for cancer is here! I…”
Source: www.instagram.comCategories: General Medicine News, Oncologists2Tweet
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Mashup Score: 4How Can We Deliver Evidence-Based and Person-Centered Cancer Care for the Transgender Community? - 7 month(s) ago
Author links open overlay panel Alison May Berner MBBS, MSc, PhD, MRCP โ โ โก Royal College of Radiologists. Improving cancer care for sexual and gender minorities. Available at:… LGBT Foundation. If we’ re not counted we don’ t count – Good practice guide to monitoring sexual orientation and trans… There are more references available in the full text version of this
Source: www.sciencedirect.comCategories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 15Trans women may be banned from women's NHS wards - 7 month(s) ago
Health Secretary promises consultation on NHS constitution, calling for a “common-sense” approach.
Source: www.bbc.co.ukCategories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 7Adaptive therapy achieves long-term control of chemotherapy resistance in high grade ovarian cancer - 9 month(s) ago
Drug resistance results in poor outcomes for most patients with metastatic cancer. Adaptive Therapy (AT) proposes to address this by exploiting presumed fitness costs incurred by drug-resistant cells when drug is absent, and prescribing dose reductions to allow fitter, sensitive cells to re-grow and re-sensitise the tumour. However, empirical evidence for treatment-induced fitness change is lacking. We show that fitness costs in chemotherapy-resistant ovarian cancer cause selective decline and apoptosis of resistant populations in low-resource conditions. Moreover, carboplatin AT caused fluctuations in sensitive/resistant tumour population size in vitro and significantly extended survival of tumour-bearing mice. In sequential blood-derived cell-free DNA and tumour samples obtained longitudinally from ovarian cancer patients during treatment, we inferred resistant cancer cell population size through therapy and observed it correlated strongly with disease burden. These data have enabled
Source: www.biorxiv.orgCategories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 1UK recommendations for the management of transgender and gender-diverse patients with inherited cancer risks - BJC Reports - 10 month(s) ago
As the rate of people openly identifying as transgender or gender diverse (TGD) is increasing, UK cancer genetics services are seeing growing numbers of TGD patients. Lack of appropriate clinical guidelines and a scarcity of robust data about the impact of gender-affirming treatments on cancer risk has led to uncertainty of how best to support TGD patients, and inequity in standards of care. To…
Source: NatureCategories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 3Pride 2023: Taking on the inequalities in LGBTQ+ cancer care - Cancer Research UK - Cancer News - 10 month(s) ago
Charities, research institutes and health providers across the UK are working to improve LGBTQ+ cancer care. Here’s how.
Source: Cancer Research UK - Cancer NewsCategories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 0Health checks are needed to reduce premature deaths among people with severe psychiatric illness, says college - 11 month(s) ago
Psychiatrists are calling on the government to close the mortality gap between people with severe mental illness and the rest of the population by ensuring that everyone with a severe psychiatric diagnosis receives an annual health check of blood pressure, blood glucose, blood lipids, body mass index, and alcohol and smoking status. The call follows an analysis by the Royal College of…
Source: The BMJCategories: Latest Headlines, Oncologists2Tweet
Pleasure chatting with Naman & Jo on @rad__chat ! We discuss #LGBTQ #cancercare , gender services and the intersection with oncology care, the work of @OUTpatientsUK and the UK Cancer and Transition Service: https://t.co/LwlLXPDqCn ๐ณ๏ธโโง๏ธ๐ณ๏ธโ๐ We also touch on busy portfolio careers! https://t.co/qLgacufKxW