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Mashup Score: 16Systolic Blood Pressure and Survival to Very Old Age: Results From the Women’s Health Initiative - 3 day(s) ago
BACKGROUND: The relationship between systolic blood pressure (SBP) and longevity is not fully understood. We aimed to determine which SBP levels in women ≥65 years of age with or without blood pressu
Source: www.ahajournals.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 4
of low-flow bypass surgery between 2003 and 2022, 215 patients with the ICAD refractory to medical treatment were finally enrolled in this study. Clinical and radiological outcomes were retrospectively evaluated, with survival analyses. RESULTS: All strokes, cerebral infarctions, and intracranial hemorrhages occurred in 12.1% (n = 26), 9.8% (n = 21), and 2.3% (n = 5), respectively, during the clinical follow-up of 54.6 ± 47.6 months (range, 0.6-237.8 months). Among all stroke events, 84.6% (n = 22) occurred within 30 postoperative days. The 2-year and 5-year cumulative risks of all strokes were 12.1% each. The mean modified Rankin Scale scores were 1.6 ± 1.1 (range, 0-5) preoperatively and 0.8 ± 1.2 (range, 0-6) at last (P < .01). The patency of direct bypass was 99.1% (n = 213) just before discharge and 96.3% (n = 184 of 191 patients with available tests) at the last angiographic follow-up of 27.0 ± 27.3 months (range, 2.3-97.3 months). All the patients with available data (n = 190) s
Source: journals.lww.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 10Brainstem Infarction Due to a Subclavian Artery Web - 3 day(s) ago
Annals of Neurology is a leading neurology journal from the American Neurological Association focusing on diseases of the human nervous system.
Source: onlinelibrary.wiley.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1
Background There have been immense advancements in the hardware and software of digital subtraction angiography systems over the last several years. These advan…
Source: journals.sagepub.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 22
Venous sinus stenting for dural venous sinus outflow obstruction due to an intrinsic filling obstruction or extrinsic stenosis is an increasingly popular treatm…
Source: journals.sagepub.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 11
Background Transcarotid artery revascularization (TCAR) is an increasingly popular technique for the management of extracranial carotid stenosis. Its off-label use in the treatment of intracranial neurovascular disease is poorly described. Our objective is to describe the use of a dedicated open transcarotid access system for the treatment of neurovascular pathologies other than extracranial carotid stenosis. Methods We conducted a retrospective review of a prospectively maintained database of consecutive patients who underwent treatment of neurovascular disease at a single academic center using the ENROUTE Transcarotid Arterial Sheath. Demographics, procedural characteristics, and patient outcomes were reported. Results Twenty patients were included in the study between September 2017 and March 2023. The following pathologies were treated: intracranial atherosclerotic disease (ICAD, nine patients), complex cervico-petrous carotid disease (five patients), intracranial aneurysms (three
Source: jnis.bmj.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 40
Intracranial atherosclerotic disease (ICAD) involves the build-up of atherosclerotic plaques in cerebral arteries, significantly contributing to stroke worldwide. Diagnosing ICAD entails various techniques that measure arterial stenosis severity. Digital subtraction angiography, CT angiography, and magnetic resonance angiography are established methods for assessing stenosis. High-resolution MRI offers additional insights into plaque morphology including plaque burden, hemorrhage, remodeling, and contrast enhancement. These metrics and plaque traits help identify symptomatic plaques. Techniques like transcranial Doppler, CT perfusion, computational fluid dynamics, and quantitative MRA analyze blood flow restrictions due to ICAD. Intravascular ultrasound or optical coherence tomography have a very high spatial resolution and can assess the structure of the arterial wall and the plaque from the lumen of the target vascular territory. Positron emission tomography could further detect infl
Source: jnis.bmj.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 19Low-profile mechanical thrombectomy devices for large vessel occlusion in pediatric ischemic stroke - 5 day(s) ago
Background Mechanical thrombectomy (MT) is a well-established treatment modality for large vessel occlusion (LVO) in adults, but there are limited data in the pediatric population. The rarity of the condition makes prospective trial design difficult, and therefore evaluation of MT devices and outcomes is sparse. In pediatric LVO cases, some newer devices may be appropriate for use in revascularization procedures. Furthermore, illustrative specific device-access combinations have rarely been presented in young patients under the age of 5 years. Methods This was a single institution experience in intracranial MT procedures for pediatric acute ischemic stroke (AIS). A given procedure was included if there was an attempt at MT between 2015 and 2023. Results Sixteen endovascular procedures were performed in 15 patients with AIS, with a mean age of 7.4 years; eight patients were <5 years of age. MT was attempted in 15/16 (93.7%) procedures, including 11 (73.3%) in the anterior circulation an
Source: jnis.bmj.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 13Ghrelin for Neuroprotection in Post–Cardiac Arrest Coma - 5 day(s) ago
This randomized clinical trial investigates if treatment of patients in a coma after cardiac arrest with the endogenous hormone ghrelin is safe and can improve neurological outcome.
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 21Acute Ischemic Stroke With Tandem Occlusion Requiring Cervical and Intracranial Revascularization - Endovascular Today - 5 day(s) ago
An interactive case study intended to emphasize the basics of medical and procedural decision-making.
Source: evtoday.comCategories: General Medicine News, NeurologyTweet
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