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    In a zebrafish model of human cutaneous and acral melanomas, CRKL amplification causes tumours to favour a fin location, indicating that tumour location is determined by both the driver oncogenes and the pre-existing positional identity gene program.

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    • @tony_breu Great thread Thanks, Maybe it has something to do with the specific mutations in a particular cancer, and their relevance regarding location. On a related note why do cancers develop in certain locations Nature 604, 354–361 (2022). https://t.co/G3y7E6A4no