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Mashup Score: 0Hypertensive Heart Failure - 10 month(s) ago
Despite overwhelming epidemiological evidence, the contribution of hypertension (HTN) to heart failure (HF) development has been undermined in current clinical practice. This is because approximately half of HF patients have been labeled as suffering from HF with preserved left ventricular (LV) ejection fraction (EF) (HFpEF), with HTN, obesity, and diabetes mellitus (DM) being considered virtually equally responsible for its development. However, this suggestion is obviously inaccurate, since HTN is by far the most frequent and devastating morbidity present in HFpEF. Further, HF development in obesity or DM is rare in the absence of HTN or coronary artery disease (CAD), whereas HTN often causes HF per se. Finally, unlike HTN, for most major comorbidities present in HFpEF, including anemia, chronic kidney disease, pulmonary disease, DM, atrial fibrillation, sleep apnea, and depression, it is unknown whether they precede HF or result from it. The purpose of this paper is to provide a con
Source: www.mdpi.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Myocardial Recovery - 1 year(s) ago
In this paper, the feasibility of myocardial recovery is analyzed through a literature review. First, the phenomena of remodeling and reverse remodeling are analyzed, approached through the physics of elastic bodies, and the terms myocardial depression and myocardial recovery are defined. Continuing, potential biochemical, molecular, and imaging markers of myocardial recovery are reviewed. Then,…
Source: MDPICategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Post-Implant Phosphodiesterase-5 Inhibitors in Patients with Left Ventricular Assist Device: A Systematic Review and Meta-Analysis - 1 year(s) ago
Background: Despite the improvement in left ventricular assist device (LVAD) technology and the advent of third-generation LVADs, hemocompatibility-related events remain a significant issue. Therefore, new pharmacological treatments are necessary to optimize patient management and to further reduce hemocompatibility-related events. The purpose of the present systematic review and meta-analysis…
Source: MDPICategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0
The nitric oxide (NO)–guanylate cyclase (GC)–cyclic guanosine monophosphate (cGMP) pathway plays an important role in cardiovascular, pulmonary and renal function. Phosphodiesterase-5 inhibitors (PDE-5i) inhibit cGMP degradation, whereas both soluble guanylate cyclase (sGC) stimulators and sGC activators directly increase sGC. PDE-5i (e.g. sildenafil, tadalafil) and sGC stimulators (e.g….
Source: SpringerLinkCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0
Multimorbidity, the coexistence of multiple health conditions in an individual, has emerged as one of the greatest challenges facing health services, and this crisis is partly driven by the aging population. Aging is associated with increased aortic stiffness (AoStiff), which in turn is linked with several morbidities frequently affecting and having disastrous consequences for the elderly. These…
Source: MDPICategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0The Neurohormonal Overactivity Syndrome in Heart Failure - 1 year(s) ago
Heart failure (HF) is categorized arbitrarily based on the left ventricular ejection fraction (LVEF) in HF with reduced (HFrEF; LVEF < 40%), mildly reduced (HFmrEF; LVEF 40–49%), or preserved ejection fraction (HFpEF; LVEF ≥ 50%). In this opinion paper, based on (patho)physiological considerations, we contend that the neurohormonal overactivity syndrome (NOHS), which is present in all symptomatic...
Source: MDPICategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0
Heart failure with preserved ejection fraction: A distinct heart failure phenotype?
Source: www.wjgnet.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 1
Heart failure with preserved ejection fraction: A distinct heart failure phenotype?
Source: www.wjgnet.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Life - 2 year(s) ago
Life, an international, peer-reviewed Open Access journal.
Source: www.mdpi.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 1Post-Implant Phosphodiesterase-5 Inhibitors in Patients with Left Ventricular Assist Device: A Systematic Review and Meta-Analysis - 2 year(s) ago
Background: Despite the improvement in left ventricular assist device (LVAD) technology and the advent of third-generation LVADs, hemocompatibility-related events remain a significant issue. Therefore, new pharmacological treatments are necessary to optimize patient management and to further reduce hemocompatibility-related events. The purpose of the present systematic review and meta-analysis…
Source: MDPICategories: Cardiologists, Latest HeadlinesTweet
🔥🔥🔥Hypertensive Heart Failure: Lessons Learned from HFpEF https://t.co/teg9HVImHE #mdpijcm via @JCM_MDPI @filpapos