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Mashup Score: 4
Purpose of Review To provide an updated review of bempedoic acid’s clinical application in lowering LDL-C in the setting of statin intolerance and the recent findings in the CLEAR Outcomes trial as well as summarize and synthesize the current state of knowledge regarding bempedoic acid while providing an in-depth analysis of the drug’s pharmacological properties, mechanism of action, clinical…
Source: SpringerLinkCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
Obesity Surgery –
Source: SpringerLinkCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 7Intrahepatic Balloon Tamponade for Penetrating Liver Injury: Rarely Needed but Highly Effective - World Journal of Surgery - 1 year(s) ago
Background Severe penetrating liver injuries are associated with high rates of morbidity and mortality. The objective of this study was to demonstrate the 15-year experience of a Level 1 US trauma center with use of intrahepatic balloon tamponade for penetrating liver injuries in adult patients. Methods Operative notes were used to identify cases employing intrahepatic balloon tamponade. Charts…
Source: SpringerLinkCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 2Belzutifan in adults with VHL-associated central nervous system hemangioblastoma: a single-center experience - Journal of Neuro-Oncology - 1 year(s) ago
Purpose Belzutifan is a selective inhibitor of hypoxia-inducible factor 2 alpha (HIF-2a) that has emerged as a targeted therapy option for Von Hippel–Lindau (VHL) syndrome-associated tumors with recent FDA approval. There is limited real-world evidence regarding safety and efficacy in CNS hemangioblastoma. Our objective was to report on our clinical experience with belzutifan in adult patients…
Source: SpringerLinkCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 9Performance Adaptations to Intensified Training in Top-Level Football - Sports Medicine - 1 year(s) ago
Because physical demands are surging in football (soccer, USA), clubs are more and more seeking players who have a high capacity to perform repeated intense exercise. High-intensity interval training (HIIT), comprising exercise performed at intensities near or exceeding the capacity of aerobic energy systems, effectively enhances the physical conditioning of players. But given that HIIT imposes…
Source: SpringerLinkCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0
Purpose We systematically reviewed visual outcomes over the last three decades in patients undergoing treatment for base of skull (BOS) meningiomas and provide recommendations to preserve vision. Methods In accordance with the PRISMA guidelines for systematic reviews, a search was conducted from 6/1/2022–9/1/2022 using PubMed and Web of Science. Inclusion criteria included (1) patients treated…
Source: SpringerLinkCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Vision preservation in skull base meningioma resection can be challenging based on tumor location. @LenoxNeurosurg found that visual outcomes in these patients have improved in recent years, likely due to more sophisticated surgical planning and technique https://t.co/Jm9c3zwfpJ https://t.co/qc6V7aFCdR
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Mashup Score: 5The role of vaccines in the COVID-19 pandemic: what have we learned? - Seminars in Immunopathology - 1 year(s) ago
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged late in 2019 and caused the coronavirus disease 2019 (COVID-19) pandemic that has so far claimed approximately 20 million lives. Vaccines were developed quickly, became available in the end of 2020, and had a tremendous impact on protection from SARS-CoV-2 mortality but with emerging variants the impact on morbidity was…
Source: SpringerLinkCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0Prospective phenotyping of CHAMP1 disorder indicates that coding mutations may not act through haploinsufficiency - Human Genetics - 1 year(s) ago
CHAMP1 disorder is a genetic neurodevelopmental condition caused by mutations in the CHAMP1 gene that result in premature termination codons. The disorder is associated with intellectual disability, medical comorbidities, and dysmorphic features. Deletions of the CHAMP1 gene, as part of 13q34 deletion syndrome, have been briefly described with the suggestion of a milder clinical phenotype. To…
Source: SpringerLinkCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 7In vivo quantitative MRI: T1 and T2 measurements of the human brain at 0.064 T - Magnetic Resonance Materials in Physics, Biology and Medicine - 1 year(s) ago
Objective To measure healthy brain $${T}_{1}$$ T 1 and $${T}_{2}$$ T 2 relaxation times at 0.064 T. Materials and methods $${T}_{1}$$ T 1 and $${T}_{2}$$ T 2 relaxation times were measured in vivo for 10 healthy volunteers using a 0.064 T magnetic resonance imaging (MRI) system and for 10 test samples on both the MRI and a separate 0.064 T nuclear magnetic resonance (NMR) system. In vivo…
Source: SpringerLinkCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Diabetes precision medicine: plenty of potential, pitfalls and perils but not yet ready for prime time - Diabetologia - 1 year(s) ago
Rapid advances in technology and data science have the potential to improve the precision of preventive and therapeutic interventions, and enable the right treatment to be recommended, at the right time, to the right person. There are well-described examples of successful precision medicine approaches for monogenic conditions such as specific diets for phenylketonuria, and sulfonylurea treatments…
Source: SpringerLinkCategories: Hem/Oncs, Latest HeadlinesTweet
👇 Check it out! Here’s an up-to-date review on Bempedoic acid and all the latest trials: https://t.co/iF1svkaDdd. #cholesterol #LDL #bempedoicacid #statin #myalgias #CLEAROutcomes #prevention #cardiology