-
Mashup Score: 0Assessment of Comorbidity Burden and Treatment Response: Reanalysis of the SCD-HEFT Trial - PubMed - 18 hour(s) ago
Increasing comorbidity burden was associated with HTE when evaluating amiodarone and ICD compared with placebo in the SCD-HeFT trial. Our results highlight the importance of enrolling diverse patient populations in clinical trials and considering the possibility of HTE when translating results to cl …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 0Medicine is difficult—there are no shortcuts - 2 month(s) ago
Delivering high quality, patient centred care requires medical training that is long enough, broad enough, and deep enough, writes Andrew Elder A senior medical leader recently gave me a piece of advice. “Even when you are bored stiff saying the same thing again and again, say it again. Even when you think everybody will be fed up hearing it, say it again. Because the politicians may not yet have heard you.” So, I will say it again. Medicine is difficult. Yes, we have fabulous imaging and more laboratory investigations than any of us can name. And yes, we can interrogate our patients’ genomes, and the genomes of the organisms and cancers that infect and affect them. But, despite all this wonderful technology, diagnosis remains difficult. Every patient is a unique individual in a unique context, a product of both their biology and their biography. Making accurate and timely diagnoses requires more than just technology—it requires listening, observation, careful thought, judgment, and ti
Source: www.bmj.comCategories: General Medicine News, CardiologistsTweet
-
Mashup Score: 1Review of the ISIS-1 Trial - 11 month(s) ago
Randomised Trial of Intravenous Atenolol Among 16,027 Cases of Suspected Acute Myocardial Infarction: ISIS-1 Lancet 1986:57-65 Background The International Study of Infarct Survival (ISIS) was an international collaboration to evaluate the effects on survival of treatments with broad applicability during the early phase of myocardial infarction. This will be the first of many trials presented by this group. Here the investigators sought to test the
Source: cardiologytrials.substack.comCategories: General Medicine News, Cardiologists1Tweet
-
Mashup Score: 1Review of the Beta Blocker Heart Attack Trial (BHAT) - 11 month(s) ago
JAMA 1982; 247:1707-14 Background Beta blockers were commonly used in the treatment of coronary artery disease by the mid-1970s, predominately for symptomatic relief of angina. Lower quality evidence was also emerging that they reduced myocardial oxygen demand, could limit infarct size and improve survival in patients suffering from an acute myocardial infarction. National Heart, Lung, and Blood Institute (NHLBI) sponsored the beta blocker heart attack trial (
Source: cardiologytrials.substack.comCategories: General Medicine News, Cardiologists1Tweet
-
Mashup Score: 2External Medicine Podcast Interview - 11 month(s) ago
An interview covering a wide array of topics near and dear to me over the course of my career
Source: andrewjfoy.substack.comCategories: General Medicine News, Cardiologists1Tweet
-
Mashup Score: 27
Collider-conditioning bias is a common concern in clinical epidemiology and can be difficult to recognize. Collider-conditioning bias is defined as the alteration in the association between an exposure and an outcome under study when conditioning on (via restriction, stratification or regression adjustment) a third factor influenced by both exposure and outcome. Collider-conditioning bias may also be induced by conditioning on a third factor influenced by causes of both the exposure and outcome of primary interest.
Source: www.jclinepi.comCategories: Cardiologists1, Latest HeadlinesTweet
See also https://t.co/whG96wiKia https://t.co/UIlIjgr0Sl