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Mashup Score: 3Why use placebos in clinical trials? A narrative review of the methodological literature - 7 day(s) ago
Researchers have a number of different options for their choice of control or comparison intervention in randomized trials. We surveyed the methodological literature looking for reasons why a researcher might choose to administer a placebo (i.e., a mimic intervention) to control subjects. Two implicit assumptions were that the issue of placebo is pertinent only to drug trials and that the nonplacebo effect of a treatment is the “real” or “true” effect. Explicit reasons given in the literature for the use of placebos were facilitating blinding and controlling for the placebo effect.
Source: www.jclinepi.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 6Guideline panel social dynamics influence the development of clinical practice recommendations: a mixed-methods systematic review - 2 month(s) ago
To synthesize empirical studies that investigate the cognitive and social processes involved in the deliberation process of guideline development meetings and determine the distribution of deliberated topics.
Source: www.jclinepi.comCategories: General Medicine News, Hem/OncsTweet-
Guideline panel social dynamics influence the development of clinical practice recommendations: a mixed-methods systematic review https://t.co/V16aeEw96W via @ShellyAnneLi et al @gbiondizoccai @Coronary4front @SABOURETCardio https://t.co/exbCuWPlEX
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Mashup Score: 0Adherence to PRISMA-A and reporting was suboptimal in meta-analysis abstracts on drug efficacy for tumors: a literature survey - 3 month(s) ago
To assess the reporting of meta-analysis abstracts on drug efficacy for tumors in terms of adherence to PRISMA-A and identify the potential factors associated with adherence to PRISMA-A.
Source: www.jclinepi.comCategories: General Medicine News, Hem/OncsTweet-
Adherence to PRISMA-A and reporting was suboptimal in meta-analysis abstracts on drug efficacy for tumors: a literature survey https://t.co/q789GRf6iG
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Mashup Score: 5Quantitative bias analysis methods for summary level epidemiologic data in the peer-reviewed literature: a systematic review - 3 month(s) ago
Quantitative bias analysis (QBA) methods evaluate the impact of biases arising from systematic errors on observational study results. This systematic review aimed to summarize the range and characteristics of quantitative bias analysis (QBA) methods for summary level data published in the peer-reviewed literature.
Source: www.jclinepi.comCategories: General Medicine News, Hem/OncsTweet-
Quantitative bias analysis methods for summary level epidemiologic data in the peer-reviewed literature: a systematic review https://t.co/28iNj6uWE7 via @JoshuaDWallach et al https://t.co/bUgnDEkzCO
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Mashup Score: 6What should journals do to prevent the publication of methodologically flawed systematic reviews? - 4 month(s) ago
Affiliations Evidence Synthesis Ireland and Cochrane Ireland, University of Galway, Galway, Ireland Centre for Health Research Methodology, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland Already an online subscriber? ☒ The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this
Source: www.jclinepi.comCategories: General Medicine News, Hem/OncsTweet-
What should journals do to prevent the publication of methodologically flawed systematic reviews? https://t.co/qJm3BTh84K via @Saif_Rahman_KM https://t.co/Wxw8j98vFM
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Mashup Score: 1Panel stacking is a threat to consensus statement validity - 5 month(s) ago
Consensus statements can be very influential in medicine and public health. Some of these statements use systematic evidence synthesis but others fail on this front. Many consensus statements use panels of experts to deduce perceived consensus through Delphi processes. We argue that stacking of panel members towards one particular position or narrative is a major threat, especially in absence of systematic evidence review. Stacking may involve financial conflicts of interest, but non-financial conflicts of strong advocacy can also cause major bias.
Source: www.jclinepi.comCategories: General Medicine News, Hem/OncsTweet-
@VPrasadMDMPH @JohnWAyersPhD @Sander_vdLinden @Walter4C @jayvanbavel @CaulfieldTim @jonathanstea @drg1985 Prof @KasperKepp & 64 other co-authors have just published an imp article in @JClinEpi "Panel stacking is a threat to consensus statement validity" https://t.co/8PL0Xs4Vk2 https://t.co/AL4K7fHlJb
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Mashup Score: 87Grilling the data: application of specification curve analysis to red meat and all-cause mortality - 6 month(s) ago
To present an application of specification curve analysis—a novel analytic method that involves defining and implementing all plausible and valid analytic approaches for addressing a research question—to nutritional epidemiology.
Source: www.jclinepi.comCategories: General Medicine News, Hem/OncsTweet-
Does red meat consumption increase mortality? A: LOL Read this analysis of the analyses. You can get any hazard ratio you like, depending on …sit down for this … analytic choices @BrianNosek et al has been replicated. H/t @skepcard https://t.co/wGI2zR7Lv2
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Mashup Score: 87Grilling the data: application of specification curve analysis to red meat and all-cause mortality - 6 month(s) ago
To present an application of specification curve analysis—a novel analytic method that involves defining and implementing all plausible and valid analytic approaches for addressing a research question—to nutritional epidemiology.
Source: www.jclinepi.comCategories: General Medicine News, Hem/OncsTweet-
Does red meat consumption increase mortality? A: LOL Read this analysis of the analyses. You can get any hazard ratio you like, depending on …sit down for this … analytic choices @BrianNosek et al has been replicated. H/t @skepcard https://t.co/wGI2zR7Lv2
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Mashup Score: 1GRADE concept paper 8: judging the certainty of discrimination performance estimates of prognostic models in a body of validation studies - 6 month(s) ago
Prognostic models incorporate multiple prognostic factors to estimate the likelihood of future events for individual patients based on their prognostic factor values. Evaluating these models crucially involves conducting studies to assess their predictive performance, like discrimination. Systematic reviews and meta-analyses of these validation studies play an essential role in selecting models for clinical practice.
Source: www.jclinepi.comCategories: General Medicine News, Hem/OncsTweet-
GRADE concept paper 8: judging the certainty of discrimination performance estimates of prognostic models in a body of validation studies https://t.co/yTaGuXTrgU via @Richard_D_Riley et al
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Mashup Score: 84Grilling the data: application of specification curve analysis to red meat and all-cause mortality - 7 month(s) ago
To present an application of specification curve analysis—a novel analytic method that involves defining and implementing all plausible and valid analytic approaches for addressing a research question—to nutritional epidemiology.
Source: www.jclinepi.comCategories: General Medicine News, Hem/OncsTweet-
Does red meat consumption increase mortality? A: LOL Read this analysis of the analyses. You can get any hazard ratio you like, depending on …sit down for this … analytic choices @BrianNosek et al has been replicated. H/t @skepcard https://t.co/wGI2zR7Lv2
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RT @BoussageonR: @EoinKr @pash22 And the importance of the placebo..., https://t.co/Ya6AphfVV4 real world data ?