The American Journal of Human Genetics: Cell Press
AJHG publishes peer-reviewed research articles relating to heredity in humans and the application of genetic principles in medicine and public policy.
AJHG publishes peer-reviewed research articles relating to heredity in humans and the application of genetic principles in medicine and public policy.
Cancer stemness, regarded as a crucial factor in tumor development, has been recognized to involve a plastic cellular state influenced by dynamic interactions between cancer…
Alruwaili et al. demonstrate that p53-mutant cancer cells accumulate DNA breaks due to post-replicative removal of thymidine analogs following DNA replication. Inhibition of PARP enhances DNA…
Dr. Jennifer A. Wargo, Dr. Nadim J. Ajami, and Dr. Carrie R. Daniel-MacDougall describe their academic and clinical work on the role of the microbiome…
Constance Jean (Connie) Eaves was a pioneering scientist with outstanding and consistent contributions throughout her long-spanning, fifty-plus-year career. Her work with over 500 publications in hematopoiesis…
Advances in biomedical research require a robust physician scientist workforce. Despite being equally successful at securing early career awards from the NIH as men, women…
Advances in biomedical research require a robust physician scientist workforce. Despite being equally successful at securing early career awards from the NIH as men, women…
Advances in biomedical research require a robust physician scientist workforce. Despite being equally successful at securing early career awards from the NIH as men, women…
Adult humans with inherited, complete FLT3L deficiency enable valuable insights into the role of the hematopoietic growth factor FLT3L in human hematopoiesis, revealing that FLT3L…
Despite the relative noisiness of polygenic indexes (PGIs), some commercial firms will use them. We offer a simple model, rooted in economic theory, to show…
To accelerate CRISPR-based targeting of RNA, Guo et al. present a resource with optimized RfxCas13d guide RNAs (gRNAs) to target messenger RNAs and noncoding RNAs in…